<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07252

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMTESTEQKLKHLMRKAWRERWTDLMWGIYVKEVIPAGSTGDTYNLAESILKQALIGPSPNSKLLSYLQYSLNVQIVSYSAVFENICLQGSIQKTRCLLELLHLLEQSLKHISCSGSADECAALASSLMSLETWLWSITSDGLKKLSEANSTSNSYTVICHYTTGLLGTLYEENYLVSLLYIARCCTNDQFAATNLASLVNQTESNIKHLAGAGNLSLENLVEPVEKVIRQCRLFENDLFKENGPEKPFYENSLCTDIHTLISWEALLRPTSDGLELTRQLEVLQKLRGYSATQLYCEILRACCLGLAETADSPGELRWAVFTFLKAPLLLLRLHRSIFGLDPNSPIGEPSPEVAVAFERLLCYPGLLETTDAKCHCNVVEGLLNEVKMRTSLLSEWHVTSILSKRESLSRGGLKLETTNTQIATLVLRAEPTVASILKTLDTDYAKNQDTLLKVLSHLLSGQSFELILNAATGTGKLRAFATKLVRFNEANRQPAGSDPSKTANSRALLFDISFLMLCRITQMYGIEVILSGELGGETFFEQWASEWLKPNQAPDLLLNRCDPMLTDQLLKALTSGESDLRSGSVRWHDACFHVPAVIREILAAYESQLVSDEEVERILDTLRTQMCCLSVCAATWLRFYIQVQPMNLKSKPTMMLDHLMTPLSLDDSKEHYRERSVLMLQIIRRLAQDDNPLQGVSDNQDQSLDHQLSKLWNKILNHGWSDHCTTLGIDRLFKIGGATWLVTSLVKAVIKEQSSDKRQRCVEGALSVAHLDLESCAISLATRVLPFLLTHSSMLASDEETGGPGGKALAQLAVLLFTAALNNQIASDSDPSTAAKKSGSKRAIDWDLNTPGFRYPPLKKVALHDDELEALCVASSTTHENKPLPNAIANLMQLMTRVAGDGIITPQLAFISYFIQTMAEITSVKTKEVMKPLLSLIPPALVFYMLAVWPGLMSISDVAKLLAHPGDEMGVGKIAARIVCAFKNTN
Length986
PositionTail
OrganismDaphnia magna
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.07
Grand average of hydropathy-0.022
Instability index39.03
Isoelectric point5.88
Molecular weight109260.76
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07252
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.72|      36|     189|     572|     614|       1
---------------------------------------------------------------------------
  572-  614 (53.07/60.21)	ALTSGESDLRSGSVRWhdACFHVPavireILAAYESQLVSDEE
  765-  800 (60.65/45.93)	ALSVAHLDLESCAISL..ATRVLP.....FLLTHSSMLASDEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.60|      44|     189|      94|     137|       2
---------------------------------------------------------------------------
   94-  119 (33.02/15.55)	.......................TRC..........LLELLHLL.EQSLKHISCSGSADE
  120-  153 (51.15/28.13)	CAALASSLMSL..ETWLWSI........................tSDGLKKLSEANSTSN
  159-  213 (45.42/24.16)	CHYTTGLLGTLyeENYLVSLlyiARCctndqfaatnLASLVNQT.ESNIKHLAGAG....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.03|      31|     191|     308|     341|       5
---------------------------------------------------------------------------
  299-  330 (50.39/34.82)	LRACCLGL...aETADSPGELRWAVFTFLKAPLLL
  333-  367 (49.64/29.64)	LHRSIFGLdpnsPIGEPSPEVAVAFERLLCYPGLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.94|      37|     454|      35|      77|       9
---------------------------------------------------------------------------
   35-   77 (50.46/52.31)	PAGStgDTYNLAESilkQALIGPSPNSKLLSYLQ.YSLNVqIVS
  494-  531 (61.48/41.27)	PAGS..DPSKTANS...RALLFDISFLMLCRITQmYGIEV.ILS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.81|      18|      22|     649|     667|      10
---------------------------------------------------------------------------
  649-  667 (27.58/22.07)	KSKPTMMLdHLMTPLSLDD
  673-  690 (29.23/17.99)	RERSVLML.QIIRRLAQDD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07252 with Med24 domain of Kingdom Metazoa
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