<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07249

Description Mediator of RNA polymerase II transcription subunit
SequenceMQQQPSPPHSPSQIKEKLLQALDRDYHVVDMALALEAVSLLEKTPVTKEALETTRLGRLVNEMRKKTKNDSLARASLVNHLRVVGVKNSVSSPALCEMGRTASPALPRPVHNLVISPTSPAFRGVTLSPALQRKPIHPAGSLQLQQQRVISPSNSVASNTSTSPGLSFSLSQTHSNSSRPSTPSSLVVKSKAISPGPGRPMIETSEFPSKTNHHRGIKRTRDNDEETMTGFELSGKRSRGSNGVDWPWVDECSRDSNLSWSGDSLRMTNHSALGGGEDRSVSSSSKASRPPRARSKIDTSIKPEPPSDVLREKFASIARVSKVKTTQELLEDLARRSGSPNLVVKPEVQPVHQQQAGAIPASTEARQWPDAKQELLDKFFRSHSTDRRNDGSTITSSIVTDEDVDLLHNGQVDSVNGTHDKNGEFHSWHETLTVASYHEDPLHLLPYVVIE
Length451
PositionUnknown
OrganismDaphnia magna
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.04
Grand average of hydropathy-0.653
Instability index56.63
Isoelectric point9.21
Molecular weight49369.68
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07249
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.23|      15|      15|     169|     183|       1
---------------------------------------------------------------------------
  153-  167 (21.76/ 7.94)	SN.SVASNTSTSPGLS
  169-  183 (25.44/10.38)	SL.SQTHSNSSRPSTP
  185-  200 (20.03/ 6.80)	SLvVKSKAISPGPGRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.31|      21|      24|      89|     111|       2
---------------------------------------------------------------------------
   89-  111 (36.65/26.39)	SVSSPALceMGRTASPALPR.PVH
  116-  137 (37.65/20.26)	SPTSPAF..RGVTLSPALQRkPIH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07249 with Med26 domain of Kingdom Metazoa
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