<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07175
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MAPIDTRVNHDAIEQQLKDIIQDLYQIMVQVSTYDSMGRPSKDVLSNEMTTLSRSLQTLHTSASAPDALPSVPPELLEYVENGRNPDIYTREFVELVRRGNQLMSGKMRAFGTFRDVLARNVATAMPELRDDVAHVVEATGGTRAAAAPNSTSNTTPAAAAATADLGSGTAAAAAAAAAAAALGAPDGAATTLG |
Length | 194 |
Position | Middle |
Organism | Beauveria brongniartii RCEF 3172 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria>
Beauveria brongniartii.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.137 |
Instability index | 37.70 |
Isoelectric point | 4.87 |
Molecular weight | 20210.38 |
Publications | PubMed=27071652
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07175
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.05| 15| 15| 158| 172| 1
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158- 172 (26.44/13.00) AAAAATADLGSGTAA
175- 189 (25.61/12.37) AAAAAAAALGAPDGA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 63.26| 20| 26| 1| 23| 2
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1- 23 (28.96/25.39) MAPIDTrvnHDAIEQQLKDIIQD
28- 47 (34.30/21.36) MVQVST...YDSMGRPSKDVLSN
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 42.29| 12| 26| 110| 121| 3
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110- 121 (21.35/12.40) AFGTFRDVLARN
139- 150 (20.94/12.05) ATGGTRAAAAPN
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 37.63| 12| 17| 66| 80| 4
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66- 80 (16.06/16.76) PDALPSvppELLEYV
86- 97 (21.57/11.63) PDIYTR...EFVELV
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