<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07168

Description Serine/threonine-protein kinase domain protein
SequenceMSFTNPPSGASGPASGSAVRNQGLKRSVQAAFEDPADRGIGYVGYQSKVRVTDKYRVIGFISSGTYGRVYKAVSRQGQPGEFAIKKFKPDKEGEQVTYTGISQSAIREMALCSELSHANVIRLVEIILEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPAATVKSIMYQLLNGCLYLHTNWVLHRDLKPANIMVTSAGQVKIGDLGLARLFYKPLHSLFSGDKVVVTIWYRAPELLLGARHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDAKKTVPFQRNQMQKIVDIMGLPTKERWPLLVNLPEYPQLSTLQPPVSSGSGSHNLHHHHHAGHTHHGGPLLSSSSSTSSSGPNSSGSSGHLEKWYYSTISQGQTSSPAQQLASSAHAGGLASLGVEGYRLLAGLLEYDPEKRLTAEKALEHPFFSTGDALTRNCFEGLKTEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLVRASKRIKE
Length485
PositionKinase
OrganismSporothrix insectorum RCEF 264
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Sporothrix.
Aromaticity0.08
Grand average of hydropathy-0.357
Instability index39.32
Isoelectric point9.11
Molecular weight53443.13
Publications
PubMed=27071652

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07168
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.67|      16|      31|     311|     326|       1
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  311-  326 (29.59/16.03)	PQLSTLQPPVSSGSGS
  343-  358 (28.08/14.86)	PLLSSSSSTSSSGPNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.23|      14|     180|     142|     157|       2
---------------------------------------------------------------------------
  142-  157 (24.28/17.45)	HDLLQiiHHHTQQPRH
  327-  340 (30.95/16.43)	HNLHH..HHHAGHTHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.99|      29|      31|     185|     215|       3
---------------------------------------------------------------------------
  185-  215 (44.61/33.75)	HRDLKPANIMVTSagQVKIGDLGLARLFYKP
  217-  245 (51.38/32.42)	HSLFSGDKVVVTI..WYRAPELLLGARHYTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.62|      31|      32|     385|     416|       4
---------------------------------------------------------------------------
  385-  416 (48.32/32.01)	L.ASSAHAGGLASLGVEGYR.LLAGL.LEYdPEKR
  417-  450 (44.30/24.67)	LtAEKALEHPFFSTGDALTRnCFEGLkTEY.PHRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.09|      14|      15|      38|      51|       5
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   38-   51 (25.23/15.73)	RGIGYVGYQSKVRV
   56-   69 (24.86/15.39)	RVIGFISSGTYGRV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07168 with CDK8 domain of Kingdom Fungi

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