<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07131

Description Uncharacterized protein
SequenceMKGEAQNCKYICCGINRFMESTRSPWTGVFQPPVSDPPLLKEQHRHLEELLNVAFSYYVKSYYYSSDTVTSVYCLGRDVGILVCALIKSPLVDIVYLIDIKVSCRHSHLLFSTAHTQRPESHLRTCEHLSRWAASNIRDVRRIRLLLMSLLDRPAIDSLEADSQEEGRQLDVSSELNDIGVSIRKIKSALDNLDKSAIKSKKQMDSRSMLPYNLVLPLDQMDVQVEGGDSLRRVDWLVGRNEACRWLRRTNYRTEAIQLSLASCGRFMRNTTLVPLSSAMDLRNLAAQQMSFALIEPNSRNPILYVKVGDIMHCLVTFGNLCMENIIVRGLDESHCAPGHTLRSRTANSGTFPRISQAMSDLLCSRAISGFSTNLLPSVDNAPEGLLPTASQLDLTTPSRHVTFVRVTEAARNALVHFATTTEPPTQLSALHQFCAWLQTYTRLFTEPCVSCEQLLGQDAALPVLRTFHTNPANARAQHEQCRPQSRLKYIQSEHFSRLLSKQSSETELLEDMRYEHRSVWDIWKSFLREYNALAMSHLKLAEVHHRLSLELKPIKSLRVGVSKRIFEQLKSLQNDLAASMQEMVKSQKIYSEEEKQAHETRLKAMNIEDKLRRRSTNIFSTMAQLHRNHVKISQRRDECENRSAGARNEYLFQLTAINAHLDHYLKTDIPDLAQILDGDVYDRFREVLSKTSEMEVDICRHHQDPFKALLKESSKIDRTTAWENFIKESPIFSVDVEFHFEPRDGDTISSLLSVNAKEGSFDQVAKKLARRFVTRERRIKSYREEINNLCSGRISPSPGVPPPPRKFPLKDYDTSEDSGALNQEYVENKVEELEFAIRREEIEKTKISACLELLKKTHGVLMRPYILLRLLLVDVQAALYEANLAAAEVETATVGGGAEVAGKVQHGASSSSTAATGSSSTEGSTVGLTGLLAESAQHRNSLLLESAFAPLNSISRSRMQNGGVCRTSAQQLANEAWARGALTLANVTTTTEPSFIQLDDKDPSSHHQPSRREPSPEVDWTGGGRLPKATAMYEFLAARSDEINMVCNERVVLLGTGDGEDWVKVRSLLDGKEGLVPRAFLSIDPTPPPAPPHPAVSALTAKGGTEQEPHDKTHLPPTPSPSDLAAPPHPPPAQCLAGQFVRALIDFAGTAEDELSFGVGAVIHVLGRRSVGEVDDGWVEGELVPLTVAETSTPPTRGVFPSMLVETVPPEETWRRRLSACRPQSAKASLSTGFTADAKISPIGERKCKPLSSSGSVPSPRSSNSGSRSKSRSASAKRSWSSGGSGQRRSTVGHNTSSSQRSSHRHQQQYHEQQGRETSAGHGRVSHSLVTAKVSPSQVPPPLEAHLLASTHQQHEFPPSTPNGEGAISSNHSHNDEEVRCFLIVILS
Length1389
PositionTail
OrganismTaenia asiatica (Asian tapeworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Platyhelminthes> Cestoda> Eucestoda> Cyclophyllidea> Taeniidae> Taenia.
Aromaticity0.06
Grand average of hydropathy-0.430
Instability index55.49
Isoelectric point7.61
Molecular weight154228.68
Publications









Function






Annotated function


GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-KW
F-actin capping protein complex	GO:0008290	IEA:InterPro
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
actin binding	GO:0003779	IEA:UniProtKB-KW

GO - Biological Process
barbed-end actin filament capping	GO:0051016	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07131
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.99|      17|     364|     115|     131|       1
---------------------------------------------------------------------------
  115-  131 (34.67/17.68)	HTQ.RPESHLR..TCEHLSR
  479-  498 (24.32/10.33)	HEQcRPQSRLKyiQSEHFSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.04|      10|      41|    1082|    1091|       2
---------------------------------------------------------------------------
 1082- 1091 (20.94/ 8.23)	LSIDPTPPPA
 1125- 1134 (22.10/ 9.09)	LAAPPHPPPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.44|      20|      44|    1307|    1329|       3
---------------------------------------------------------------------------
 1307- 1329 (31.16/28.74)	HQQqyHEQQGrETSAGHGRVS..HS
 1353- 1374 (35.27/19.94)	HQQ..HEFPP.STPNGEGAISsnHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.24|      14|      15|    1273|    1286|       6
---------------------------------------------------------------------------
 1223- 1236 (22.83/10.89)	RPQSAKASLSTGFT
 1273- 1286 (25.48/13.01)	RSASAKRSWSSGGS
 1290- 1303 (21.93/10.18)	RSTVGHNTSSSQRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.08|      23|     391|     759|     809|       7
---------------------------------------------------------------------------
   15-   37 (44.38/12.44)	INRFMESTRSPWTGVFQPPVSDP
  787-  809 (47.70/59.36)	INNLCSGRISPSPGVPPPPRKFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.38|      11|      15|     226|     236|       8
---------------------------------------------------------------------------
  226-  236 (20.97/13.50)	EGGDSLRRVDW
  242-  252 (22.41/14.99)	EACRWLRRTNY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.96|      62|     364|     323|     403|       9
---------------------------------------------------------------------------
  331-  401 (93.88/99.18)	LDESHCAPGHT.lRSRTANSGTFPRISQAMSDLLCSRaisGFSTnlLPSVDNAPEgllPTASQLDLTTPSRH
  944- 1007 (104.08/58.86)	LLESAFAPLNSisRSRMQNGGVCRTSAQQLANEAWAR...GALT..LANVTTTTE...PSFIQLDDKDPSSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.75|      26|     369|     814|     851|      10
---------------------------------------------------------------------------
  818-  851 (35.50/39.23)	DSGALNQEYVEnkveelefAIRREEIEKTKISAC
 1197- 1222 (47.25/23.95)	TRGVFPSMLVE........TVPPEETWRRRLSAC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.06|      29|     593|     265|     293|      11
---------------------------------------------------------------------------
  265-  293 (50.80/37.31)	GRFMR.....NTTLVPLSSAMDLRNLAAQQMSFA
  860-  893 (40.26/27.92)	GVLMRpyillRLLLVDVQAALYEANLAAAEVETA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.65|      19|     365|     634|     662|      12
---------------------------------------------------------------------------
  610-  628 (32.79/19.99)	DKLRRRSTN.....IFS.TMAQLHR
  638-  662 (22.86/23.80)	DECENRSAGarneyLFQlTAINAHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.94|      21|     593|     152|     188|      13
---------------------------------------------------------------------------
  156-  176 (33.01/44.68)	IDSLEADSQEEGRQLDVSSEL
  190-  210 (33.93/ 8.63)	LDNLDKSAIKSKKQMDSRSML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.36|      15|      15|     414|     428|      15
---------------------------------------------------------------------------
  414-  428 (26.36/16.50)	ALVHFATTTEPPTQL
  430-  444 (29.00/18.91)	ALHQFCAWLQTYTRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.12|      20|      41|     697|     716|      18
---------------------------------------------------------------------------
  696-  715 (34.27/18.22)	EVDICRHHQ....DPFKALLKESS
  716-  731 (23.88/10.66)	KID....RT....TAWENFIKESP
  734-  757 (22.97/10.00)	SVDVEFHFEprdgDTISSLLSVNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07131 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DGWVEGELVPLTVAETSTPPTRGVFPSMLVETVP
2) EPSFIQLDDKDPSSHHQPSRREPSPEVDWTGGG
3) GGAEVAGKVQHGASSSSTAATGSSSTEGSTVGLTG
4) PRAFLSIDPTPPPAPPHPAVSALTAKGGTEQEPHDKTHLPPTPSPSDLAAPPHPPP
5) SPIGERKCKPLSSSGSVPSPRSSNSGSRSKSRSASAKRSWSSGGSGQRRSTVGHNTSSSQRSSHRHQQQYHEQQGRETSAGHGRVSHSLVTAKVSPSQVPPPLEAHLLASTHQQHEFPPSTPNGEGAISSNHSH
1177
993
897
1078
1242
1210
1025
931
1133
1375










Molecular Recognition Features






MoRF SequenceStartStop




NANANA