<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07115

Description Uncharacterized protein
SequenceLKPELPPKSPMLGSSDLLTAYDLGAVYSRYCGAKKMREDLNSFLPQIYGNFNFSQAQDISSLKMLVEKPPITGKEINTLSSTAMSGFRLTPGPVDERYRYLFEKKREGDGMPVIYDVERKDYSGGQRYKNSLDSLDGDEPERKKHKSEKKEKKKKKDKKKKDKLNQNTFDIEYSCGLIIATAVLLERAIYCDYTASARAIRPFENYILDHVLPLYGNTHSSVTVTSEQTTLFVHEARQEIRAMTGAGDGDNVLFVGSGSTAAVELLIHLMQPEKLVVILSTHEHHSNTLPWRAVAEACYYVQESADGGIDHNDLIRVLEKVSQTHPQSQLLAAFTACSNITGICMDVPKISATLKKYKALSVWDYASSAPYVEINVNGTHPVDAAFFSGHKFVGGVSTPGVLIVKKALIKATVPKRVGGGTVFFVSPSGEWYLKDAEYREEGGTPDSVGIIRLALAVKLKRAVGEGTIEALERQKSERFLMGLRSCHNVVLLGAPRVDHRLAVFSFLVKDQHSGLFFHHNYISALLNDLFGIQSRAGCMCAGPYAQYLMAIDEELALQYLAALREADGLDRTHLRRVGEYSSNEMLRPGFTRVSIPYFWTDDQYQLNCESAEWHHYKQRTFHARKWLGYISFNKAHRLANESLAAMERVPVPDGRSAVDDRYAYLRWFVLPVEAVQIVPDGDSQSEHEVFPKESESENQCQSCDFAKDVVAECPLNPADSNKGLLEEFGTDEEPEDAKVLDDWDKRVVVRHRQLTAAEEVRIPWHQPPLEMYRRVSEAIHGLDMIKEGDKILVCLSGGKDSLSLLHILHFYQMRCRKNKSTNFELGAITVDPGSTAYNPRPLIDYCRSLNIDYFYEEQDIIGAAKKLNNVRSICAFCSRMKRGRLAAAAQLHGWNVLAMGQHLDDVAESFFIAAFQNGNLSTMKAQYLSRDGTLRVIRPLIFVRERALREFAESKGLPVVAENCPACFNQATERHRIKQLLAQQELIFPDLFNSLRSALRPLLLVDSARTDEMRALAIENITIPCAAYNPRPLIDYCRSLNIDYFCEEVALDIIGAAKKLNNVRSICTFCSRTKGGRLAAAPQLHGWNVLAIGQHLDEVAERTYHTTDVDRYAAIDEHPCSAAEGFSEITWKSKENYSLQPIKLFDQAKRILLTFEESVNLRPDVTHFVLSRLISFGVAFVKVCYENGKTIDDLVWWRENDFEDTA
Length1206
PositionHead
OrganismHaemonchus placei (Barber's pole worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Trichostrongyloidea> Haemonchidae> Haemonchus.
Aromaticity0.09
Grand average of hydropathy-0.305
Instability index43.31
Isoelectric point6.40
Molecular weight135824.18
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
catalytic activity	GO:0003824	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
tRNA binding	GO:0000049	IEA:UniProtKB-KW
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07115
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      51.89|      10|      23|     861|     870|       1
---------------------------------------------------------------------------
  861-  870 (18.74/11.55)	IGAAKKLN..NV
 1054- 1063 (18.74/11.55)	IGAAKKLN..NV
 1078- 1089 (14.41/ 7.04)	LAAAPQLHgwNV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     243.14|      71|     190|     816|     908|       2
---------------------------------------------------------------------------
  816-  908 (119.48/108.37)	RKNKSTNFELGAITVdPgSTAYNPRPLIDYCRSLNIDYFYEE..QDIigaakklnnvRSICAFCSRMKRGRlaaaaqlhGWnvLAMGQHLDDVAE
 1009- 1101 (123.67/81.25)	RTDEMRALAIENITI.P.CAAYNPRPLIDYCRSLNIDYFCEEvaLDIigaakklnnvRSICTFCSRTKGGRlaaapqlhGWnvLAIGQHLDEVAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.58|      10|      24|     647|     656|       3
---------------------------------------------------------------------------
  647-  656 (20.45/12.95)	ERVP.VPDGRS
  673-  683 (15.14/ 7.58)	EAVQiVPDGDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.89|      15|      22|     965|     981|       4
---------------------------------------------------------------------------
  965-  981 (23.59/24.12)	PACFNqaTERHRIKQLL
  989- 1003 (26.30/18.53)	PDLFN..SLRSALRPLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.28|      50|     537|     222|     271|       7
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  222-  271 (82.45/56.23)	VTVTSEQTTLFVHEARQE.IRAMTGAGDGDNVLFVGSGSTAAVELL..IHLMQ
  760-  812 (80.83/54.98)	VRIPWHQPPLEMYRRVSEaIHGLDMIKEGDKILVCLSGGKDSLSLLhiLHFYQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07115 with Med19 domain of Kingdom Metazoa

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