<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07100

Description Uncharacterized protein
SequenceMGTNTEVATASSTSLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDMLACSEAVKLLRTMTDEEKAQCCKASLSLLSNKDDPRYIHYERILSSIFMAACNEGVLPLSDCCELLILCTNFTLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSSNSRAFLLPRVAKKFNDMFISFRPLTEMVTVIGRPWLYPVAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTNLTPQRLQCDELLHMIILEAMSEMEKTETRLDDPANQYQWMNITQTVTFSLLHGNAAFSRLLKILYESLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSHTEVLPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAVDVFLDGSPEEMNTVWHLPHGIISYPKKAPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSVQQTQKLPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLASVNKNANLGSAQQDRSRDLLFVLCDILSYRFISYPFPVGSKVNLMLWCYTALGNSQVQMNIALCSALEQVMLRYWMWNSPQEMFYLSNAFLGKQGKLAVIFNTANPAFCDSQHGNVPIEQQYTNSHVSLELLRCLLLSMFRSLKMTGMEMTAEMVQRCNVNFCWPLSINRTYSSQLIGCNVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSVLSSMNSKELTATINKFTDYFIFIFKKNLPSDDQQFAAMIGILNDMAFNLHLIPLDRLLTSLVLHPTDDGATEIAMLIIHSLVGSYPDLHNRITALVHIIPSNKIGNTSAAFFNKMSEYYSQFPELSYREMEAKMRREMQIELGMRPIEQPTVSPELHMPIYYGNIMERILPIVDIILLRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPAFAYKDWRFAEIPPAGQALTGACIELLASPHAPVITAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYEHIVSVLDSEALHGDPSVCFGSLESECFLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGVLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRDKLKYISHTPINATVDLPHKLAPGPSRSKCCETGVWMEHGAASHTVQFSQTMKLIRGSSWYWGNMSWRDAEKVLMNQLPGTYLVRDSASDRYIFTISYRTKHSVHHTRLAQHGGNFCLGGPNSLVKANSLVSFIENSLQSCGRRRICMLMHPKSDSTGIEILELNHLLHRHELLPSLKYLCRVVIRNCVEKELLPSLPLPPNMICYLEDPKYFEMLEAYAALKYLKRYSTIFAMSSGALPAAISVIRISGKESRRCLEELTGRKKILPRQLFYANIQRDGELIDRGMAVFLPGPKTSTGEDVAEFYVHGSRAVVDCLLEALAQIDNVQPAKAGEFTRR
Length1732
PositionTail
OrganismElaeophora elaphi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Elaeophora.
Aromaticity0.09
Grand average of hydropathy-0.016
Instability index44.75
Isoelectric point6.48
Molecular weight197113.31
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07100
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.73|      36|      40|     552|     591|       1
---------------------------------------------------------------------------
  552-  582 (47.12/31.77)	..........PLPL.SLIDSLTFHARNHLFQLCLLKLTAMLS
  587-  619 (44.60/37.07)	QKLPS.........pATIDTLVRLAVTTEFEYGVKQVLALLS
  620-  647 (24.01/ 7.46)	STLASvnknaNLGS.AQQD....RSRDLLFVLC.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.34|      25|      40|     144|     181|       2
---------------------------------------------------------------------------
  144-  181 (41.13/53.99)	LHLIDykglrnilkllvvERMQEVPS..TITHHHR......HMLLP
  187-  219 (35.21/21.67)	LTLID.............RQLNLLPCifTITELHRvssnsrAFLLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.16|      20|      36|     245|     264|       3
---------------------------------------------------------------------------
  245-  264 (40.51/25.08)	PWLYPVAAHISFPVST....PSWK
  279-  302 (31.65/17.84)	PYKSELFAPQSFLLYTllrqPRGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     245.78|      82|     627|      36|     141|       4
---------------------------------------------------------------------------
   36-  141 (129.12/135.79)	GVQMREMFW...DLSK.DVDVDMLACS..EAVKLLRTMTDEekaqcckaslsllsnkddPRYIHYeriLSSIFM...............AACN..EGVLPL......SDCCELLILCtnfTLTTPMDSRKFEYMQ
  662-  772 (116.66/77.89)	GSKVNLMLWcytALGNsQVQMNIALCSalEQVMLRYWMWNS..................PQEMFY...LSNAFLgkqgklavifntanpAFCDsqHGNVPIeqqytnSHVSLELLRC...LLLSMFRSLKMTGME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.28|      43|     626|     309|     412|       5
---------------------------------------------------------------------------
  369-  412 (69.10/156.25)	AAFSRLLKILYESLSETVYR....KGRDElMWVILQYVAVYIDRVSNE
  985- 1031 (73.18/30.03)	AAFFNKMSEYYSQFPELSYRemeaKMRRE.MQIELGMRPIEQPTVSPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.98|      30|      33|    1115|    1146|       9
---------------------------------------------------------------------------
 1115- 1145 (49.64/31.47)	LEDR...DGKYALLTPSFISDNHQLS.LPSQfCQA
 1146- 1179 (47.34/29.11)	LVDRilqASNYAHQPPAFAYKDWRFAeIPPA.GQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      39|    1265|    1284|      10
---------------------------------------------------------------------------
 1265- 1284 (34.66/24.69)	LLTENQLLTNLALGHAYLQH
 1305- 1324 (32.89/23.00)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07100 with Med23 domain of Kingdom Metazoa
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