<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07097

Description Uncharacterized protein
SequenceMKSLNVTSWHHQTPERRPLKRNRLGPPDVYPQDIKQEEDNLGADRLKKGYQIAVTSYEHDSIVWNAKMPRLDKMDDSMIRCAQIIMQIMAKKNELNANLDKERKRGAKEGIFQNFSHTVGQSVKSKERKEWFTDLARGKSLSYLARRPPFFRKKEDALEYLCDFKVPVTRALWFLKLIAVGQGIASNVNKQKKSTADQLAAEHAVLFSKYVKLMLNQMSESAKLETNIVYTERWPHFVCLCKHAYEDGMVERQEFLMDLCDIFADRFVQRSENRPHFFILFRMFLSFFAQYADQITQNLILSRRCAFLIARRLAIYKKESEDTLGRISIFFVFRIIDAAELFEDLLQCQKQRPIILILCGLLYGILIDCPGALIWNNFHVAEGRPPSLLHQLCASPLDHLPCEIEALPMPAGVGTDKIMHFIHLRVEEVKRRSHNVENHWSLNQTQKDGFALIVRVCLEILGVLDSARHDQPHSIERIYNLIFSGPSKESFEHEHAIRVKVLLHWAVTVEREGTHRASIVASVLALRINHRKGFRFGQFKFLKNINKFFSLIFVNIFAGNHHLQDILVEYLETESPQPGQPYFYEEFSNLMHLFVELLRAGVFSHDLYVKSLITTGEMMESLPIVPRIRARNSDKTKCSLNPCFGEKFDSTMAIKDEYAVNVERSIKVGNAAKIQGYRLEKDENLFTHSMLGPELSIHERFLIHLPIPQLSEYRGECNQRLLLLYGMGDERDNVKNELKKIAREIAKIWTKRIVVEFSFSKPSEIRFKKRTNREQINESIQKFRSQTYYDQVVLCGWCCDNFISMITDFVHHQGTVLPTAEGLDILLDMMEQCKNIYGIMEFAEELLPLLVAVERVISERRVDCVPSIISTQLGYVLVGYISHNYYYFLLSENAPEIVNGLYQIIESQLKSSDACLTGWGRTIAIFILNAKRELIEAALTNKKIEGKREVLLRILPPRKPSCISVNAIYHACLFKESLDKTKRIFSFNDYRRLNALFDGPDARYSFVISALRAAKQCERDFDRLVELANICGHVSAQTGISAEWCGAIQALCCSSVAGNHGFADLLLAINVEDSSCHYSIATFYMLLASRSCFSMNALFHQLLHTALSSLLKSDSSKADVDAEAGVCLALLVLAAIVCQSDEPIELPLGYNGKSEEKKKYVSGNADRWVLSGGHLHDISDAIFDLLFTICLLADYTKNKLRDRIEEKIDHCFRREYISQISKAVLIAMCEQDWVTHRIYRVCEETNMDVFNSHKLKKNCLGQQLLRMTLRRKCEQTIIQELTVCNGNSKKSLIDKLFDVLNIWNIRATYFDLKLMIKEISPEGSSSKHAQQQAIAADALIGEIGKCCRDLFTLSRKSESKLPEAGVGKAFRLRHITKYWLISPLVHVCPKPVNLPQSFPAITVQSKFLKEAASMLDTANDNSRERIQQSAWLLSQEPFINLVLTCLKSEEQQRDGLVGSLLKQLQDLALKSKENPTLPYLRTFSLEREGLLLRLSLVGGMFDSVCHPANSDSWALLLFQLMLYGVVSKERDRVLFDSCYDMLSTLLVWSITDPMSAIPINSQDPDTKYRFNNYSSFVRKLRKELNERALIPELRSLMQFLPLPKPSFDIITCEPYGTVSLSPQKLAKGQIGPSTKVIKQGLQFSEKVKISTFDMIQNFNTEVSVKRTWNWAMFQAVKSDRLPIPVQRYIQRLIQHQHYNEFVRPTICGMDRPPNLDIYLSPPIMDVSETPISIHHVPANSAAPISTSASVASISSTASTSIASNASLAGVDQSASNVAAQNRAFQADNSQLSVSQDPNNDAVMFAQPSHIPSIPEMSRVQSSASPRGSRGGRRKNAAGPASRSQGTTRKKQRQLADQMQMQSSAPQMSGPVITAPNNSAASTYGWGPQPIQISQMQQYSNSSQAGAINQSEDSKMKIHSMILQKRQQAQAASGGSQNVGGGPSNLAEINNYQSMGHSEPSGQYGAAMLMKMENPNIEQPYSMGPPQMVLSQEQQTTQFAPQQRVYSHQQAQNASNMFDNRMMAQQAMQYGQQQYQQRF
Length2038
PositionKinase
OrganismDracunculus medinensis (Guinea worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Dracunculoidea> Dracunculidae> Dracunculus.
Aromaticity0.08
Grand average of hydropathy-0.264
Instability index47.35
Isoelectric point8.70
Molecular weight231277.42
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07097
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.14|      64|     253|     546|     615|       1
---------------------------------------------------------------------------
  546-  615 (100.93/88.28)	NKFFSLI..FVN....IFAGNHHLqDILVEYLETESPQPGQPYFYEEfsnLMHLFVELLRagVFSHDLY..VKSLITT
  800-  871 (96.22/65.03)	DNFISMItdFVHhqgtVLPTAEGL.DILLDMMEQCKNIYGIMEFAEE...LLPLLVAVER..VISERRVdcVPSIIST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     167.65|      35|      35|    1877|    1911|       2
---------------------------------------------------------------------------
 1872- 1903 (50.35/35.34)	...ITAPN.........NSAASTY....G.................WGPQPIQISQMQQYSNSSQ
 1904- 1936 (48.26/33.48)	AGAINQSE.........DSKMKIH....S.................MILQKRQ..QAQAASGGSQ
 1940- 2000 (38.00/24.38)	GGPSNLAEinnyqsmghSEPSGQY....GaamlmkmenpnieqpysMGPPQMVLSQEQQTTQFAP
 2001- 2034 (31.04/18.21)	QQRVYSHQ........qAQNASNMfdnrM.................MAQQAMQYGQ.QQY.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.16|      14|      40|     128|     141|       3
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  128-  141 (25.99/15.70)	RKEWFTDL.ARGKSL
  170-  184 (21.16/11.41)	RALWFLKLiAVGQGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.99|      22|     129|     954|     978|       4
---------------------------------------------------------------------------
  954-  978 (31.71/31.21)	ILPPRkpSCISVNAIYHAcLFKESL
 1086- 1107 (40.28/24.69)	LLASR..SCFSMNALFHQ.LLHTAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.90|      17|      20|    1748|    1764|       6
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 1732- 1748 (25.52/17.56)	SIHHVPANSAAPISTSA
 1749- 1765 (24.32/16.34)	SVASISSTASTSIASNA
 1766- 1781 (19.07/10.94)	SLAGVDQSASNVAAQN.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.48|      19|      20|     267|     285|       7
---------------------------------------------------------------------------
  267-  285 (35.85/22.68)	FVQRSENRPHFFILFR..MFL
  288-  308 (27.63/15.72)	FAQYADQITQNLILSRrcAFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.24|      27|      42|     432|     458|       8
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  432-  458 (49.28/29.07)	RSHNVENHWSL..NQTQKDGF....ALIVRVCL
  471-  503 (35.96/19.33)	QPHSIERIYNLifSGPSKESFehehAIRVKVLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.64|      69|     119|    1327|    1443|       9
---------------------------------------------------------------------------
 1327- 1404 (99.70/132.63)	KHAQQQaiaADALIGEIGKCCRDLfTLSRKSESKLPEAgvgKAFRLRH...ITKYWLISPLV.HVCpKPVNlPQSFPAITVQ
 1447- 1519 (108.95/51.74)	KSEEQQ...RDGLVGSLLKQLQDL.ALKSKENPTLPYL...RTFSLEReglLLRLSLVGGMFdSVC.HPAN.SDSWALLLFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.92|      19|     119|    1169|    1200|      10
---------------------------------------------------------------------------
 1169- 1190 (28.09/34.91)	VLSGGHLHDISDAIfdlLFTIC
 1211- 1229 (33.83/12.16)	CFRREYISQISKAV...LIAMC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.95|      13|      42|    1815|    1830|      12
---------------------------------------------------------------------------
 1815- 1830 (12.17/21.96)	EMsRVQSSAsPRGSrG
 1857- 1869 (26.78/18.16)	QM.QMQSSA.PQMS.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.59|      39|      42|     999|    1038|      13
---------------------------------------------------------------------------
  999- 1038 (63.77/54.67)	GPDARYSFVISALRAAK.QCERDFDRLVELANI....CgHVSAQT
 1039- 1082 (61.82/46.89)	GISAEWCGAIQALCCSSvAGNHGFADLLLAINVedssC.HYSIAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.07|      13|      15|    1701|    1713|      16
---------------------------------------------------------------------------
 1701- 1713 (26.15/14.66)	FVRPTICGMDRPP
 1718- 1730 (23.92/12.79)	YLSPPIMDVSETP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.05|      22|      37|     673|     694|      17
---------------------------------------------------------------------------
  673-  694 (38.86/21.63)	KIQGYRLEKDENLFTHSMLGPE
  709-  730 (39.18/21.87)	QLSEYRGECNQRLLLLYGMGDE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07097 with Med12 domain of Kingdom Metazoa
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