<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07095

Description "BMA-SUR-2, isoform c"
SequenceMGTTTEAIATSATSLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDVLACSEAVKMLRTMTEEEKTQCCKASLSLLSNKDDPRYIHYERILSSIFMIACNEGVLPLSDCCELLILCTNFSLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSNNSRAFLLPRVAKKFNDMFISFRPLTEMVTIIGRSWLYPIAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTSLTPQRLQCDELLHMIILEAMSEMEKTDTRLDDPANQYQWMNITQTLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSHTEILPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAVDVFLDGSPEEMNTVWHLPYGIISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSIQQAQKVPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLASVNKSTNLGPAQQDRSRDLLFVLCDILSYRFISYPFPVGSKINLMLWCYTALGNSQVQMNIVLCSALEQVMMRYWMWNSPQEMFYLSNAFLGMEMTAEMMQRCNVNFCWPLSINRTYSSQLIGCNVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSVLSSMNNKELTATINKFTDYFIFIFKKNLPSDDQQFTAMIGILNDMAFNLHLIPLDRLLISLVLHPTDDGATEIAMLIIHSLVGSYPDLHNRITALVHIIPSNKIGNSGAAFFNKMSEYYSQFPELSYREMEAKMRREMQIELGMRPIEQSTVNPELHMPIYYGNIMERILPIVDIILLRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPAFVYKDWRFAEMPPAGQALTGACIELLASPHAPVITAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYDHIVSVLDSEALHGDPSVCFGSLESECLLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGLLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRNKLKYISHTQMNTAIDLPHKLAPGPSNLDVVRRDVWMEHGAASHTVQFSQTMKLIRGSSWYWGNMSWKDAEKVLMSQLPGTYLVRDSASDRYIFTISYRTKHSVHHTRLAQHGGNFCLGGPNSLVKANSLVSFIENSLQSCCKRRICMLMHPKSDSTGIETLELNHLLRRHELLPSLKYLCRVVIRNCVEKELLASLPLPSNMICYLEDPKYFVPPCLYQICIYNGIMFILIFVLANNQALIMK
Length1561
PositionTail
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.09
Grand average of hydropathy0.017
Instability index45.08
Isoelectric point6.27
Molecular weight178544.50
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07095
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.14|      35|      39|     536|     574|       1
---------------------------------------------------------------------------
  523-  560 (46.91/32.48)	ISYSKKTPL....P..lsliD..sLTFHARNHLFQLCLLKLTAMLS
  561-  597 (47.36/30.20)	IQQAQKVPS....PAT.....idtLVRLAVTTEFEYGVKQVLALLS
  598-  625 (18.87/ 6.41)	STLASVNKStnlgPAQ...qD......RSRDLLFVLC.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.60|      29|      33|    1038|    1069|       2
---------------------------------------------------------------------------
 1040- 1069 (48.51/41.49)	DR...DGKYALLTPSFISDNHQLS.LPSQfCQAL
 1071- 1103 (47.09/27.64)	DRilqASNYAHQPPAFVYKDWRFAeMPPA.GQAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      38|    1188|    1207|       3
---------------------------------------------------------------------------
 1188- 1207 (34.66/20.23)	LLTENQLLTNLALGHAYLQH
 1228- 1247 (32.89/18.85)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.37|      33|      40|     883|     920|       4
---------------------------------------------------------------------------
  898-  939 (47.08/40.52)	IPSNKIGNSGAAFFNKMSEYYsqfpelsyrEMEAKMRREMQI
  941-  974 (52.29/35.04)	LGMRPIEQSTVNPELHMPIYY........gNIMERILPIVDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.33|      21|      29|     168|     195|       6
---------------------------------------------------------------------------
  154-  176 (33.41/33.85)	NILKLLVVERMQevPS..TITHHHR
  184-  208 (28.92/11.43)	NMLLTLIDRQLNllPCifTITELHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     167.25|      45|      66|     294|     340|      13
---------------------------------------------------------------------------
   50-   73 (26.95/11.50)	.....................VDVDVLACSEAVKM...LRTMTEEEKT
  294-  340 (71.12/49.74)	TLLRqpRGKDTISYVMRQNTSLTPQRLQCDELLHMI.ILEAMSEMEKT
  363-  408 (69.17/41.85)	TVYR..KGRDELMWVILQYVAVYIDRVSNEEMVRVAeIYNLLYSDEQT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07095 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA