<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07095

Description "BMA-SUR-2, isoform c"
SequenceMGTTTEAIATSATSLTAAVGNDAEKLQWIVLNQVEGVQMREMFWDLSKDVDVDVLACSEAVKMLRTMTEEEKTQCCKASLSLLSNKDDPRYIHYERILSSIFMIACNEGVLPLSDCCELLILCTNFSLTTPMDSRKFEYMQKNLHLIDYKGLRNILKLLVVERMQEVPSTITHHHRHMLLPVENMLLTLIDRQLNLLPCIFTITELHRVSNNSRAFLLPRVAKKFNDMFISFRPLTEMVTIIGRSWLYPIAAHISFPVSTPSWKLEVTTTRLHQRAHLPYKSELFAPQSFLLYTLLRQPRGKDTISYVMRQNTSLTPQRLQCDELLHMIILEAMSEMEKTDTRLDDPANQYQWMNITQTLSETVYRKGRDELMWVILQYVAVYIDRVSNEEMVRVAEIYNLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNSHTEILPKPSESLWRQIQFLQERTADSDPNIQNVADHNAVLAAVANAYSSDMPNFQKLVLTAVDVFLDGSPEEMNTVWHLPYGIISYSKKTPLPLSLIDSLTFHARNHLFQLCLLKLTAMLSIQQAQKVPSPATIDTLVRLAVTTEFEYGVKQVLALLSSTLASVNKSTNLGPAQQDRSRDLLFVLCDILSYRFISYPFPVGSKINLMLWCYTALGNSQVQMNIVLCSALEQVMMRYWMWNSPQEMFYLSNAFLGMEMTAEMMQRCNVNFCWPLSINRTYSSQLIGCNVDDGAADTVIYDELMHRVIQEVHQVQEIIYAQGLAAEEQLLKFFSGERRQTIFCVVYNMLFETKKIHPVIYSVLSSMNNKELTATINKFTDYFIFIFKKNLPSDDQQFTAMIGILNDMAFNLHLIPLDRLLISLVLHPTDDGATEIAMLIIHSLVGSYPDLHNRITALVHIIPSNKIGNSGAAFFNKMSEYYSQFPELSYREMEAKMRREMQIELGMRPIEQSTVNPELHMPIYYGNIMERILPIVDIILLRAIETVVADQLFTTLLMCFKPCYRYHPQPAAYMYSVLYCLDKTISHTVRARDFVLEICGQLEDRDGKYALLTPSFISDNHQLSLPSQFCQALVDRILQASNYAHQPPAFVYKDWRFAEMPPAGQALTGACIELLASPHAPVITAHALIDLVFIRPLHQPYATINAVALILTALPVSFQQVFYDHIVSVLDSEALHGDPSVCFGSLESECLLLTENQLLTNLALGHAYLQHCNTSSLAALPEFVRDQLAPKLVTEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAVDVYKMTVKVNERVGLLKYEDSICDFLYHMKYMYVGDFVKNEAEQAIQRLSPSMRNKLKYISHTQMNTAIDLPHKLAPGPSNLDVVRRDVWMEHGAASHTVQFSQTMKLIRGSSWYWGNMSWKDAEKVLMSQLPGTYLVRDSASDRYIFTISYRTKHSVHHTRLAQHGGNFCLGGPNSLVKANSLVSFIENSLQSCCKRRICMLMHPKSDSTGIETLELNHLLRRHELLPSLKYLCRVVIRNCVEKELLASLPLPSNMICYLEDPKYFVPPCLYQICIYNGIMFILIFVLANNQALIMK
Length1561
PositionTail
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.09
Grand average of hydropathy0.017
Instability index45.08
Isoelectric point6.27
Molecular weight178544.50
Publications
PubMed=17885136

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07095
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.14|      35|      39|     536|     574|       1
---------------------------------------------------------------------------
  523-  560 (46.91/32.48)	ISYSKKTPL....P..lsliD..sLTFHARNHLFQLCLLKLTAMLS
  561-  597 (47.36/30.20)	IQQAQKVPS....PAT.....idtLVRLAVTTEFEYGVKQVLALLS
  598-  625 (18.87/ 6.41)	STLASVNKStnlgPAQ...qD......RSRDLLFVLC.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.60|      29|      33|    1038|    1069|       2
---------------------------------------------------------------------------
 1040- 1069 (48.51/41.49)	DR...DGKYALLTPSFISDNHQLS.LPSQfCQAL
 1071- 1103 (47.09/27.64)	DRilqASNYAHQPPAFVYKDWRFAeMPPA.GQAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      38|    1188|    1207|       3
---------------------------------------------------------------------------
 1188- 1207 (34.66/20.23)	LLTENQLLTNLALGHAYLQH
 1228- 1247 (32.89/18.85)	LVTEAQLIFVLRLVVPILQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.37|      33|      40|     883|     920|       4
---------------------------------------------------------------------------
  898-  939 (47.08/40.52)	IPSNKIGNSGAAFFNKMSEYYsqfpelsyrEMEAKMRREMQI
  941-  974 (52.29/35.04)	LGMRPIEQSTVNPELHMPIYY........gNIMERILPIVDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.33|      21|      29|     168|     195|       6
---------------------------------------------------------------------------
  154-  176 (33.41/33.85)	NILKLLVVERMQevPS..TITHHHR
  184-  208 (28.92/11.43)	NMLLTLIDRQLNllPCifTITELHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     167.25|      45|      66|     294|     340|      13
---------------------------------------------------------------------------
   50-   73 (26.95/11.50)	.....................VDVDVLACSEAVKM...LRTMTEEEKT
  294-  340 (71.12/49.74)	TLLRqpRGKDTISYVMRQNTSLTPQRLQCDELLHMI.ILEAMSEMEKT
  363-  408 (69.17/41.85)	TVYR..KGRDELMWVILQYVAVYIDRVSNEEMVRVAeIYNLLYSDEQT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07095 with Med23 domain of Kingdom Metazoa
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