<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07091

Description Uncharacterized protein
SequenceMEKEDIMERQEQKPVMNSAQCDKYSAVDLSLEEVEEEIRLEKIRQTSLKFSWDYLSQLLRRNLMEKRFVLSADDKEDLMQAAADMRKYMPSDSDRDLSTHLRHLAESLSSDFQAHPGYYKIRNADFSLEITVSLDGQQITSCSVSWFGERAVEAQALRLYVSRNRWDLIHTALTAMFHLVPSDLSRDEKIYCLRSLEYAEKDLLNMSGSAPSIFEQINGGILGLCKPRTESTPFTIYPFVEPVIFLDAASGGIISPTDEQVLYDVEPYLQLCVVSSSTPNFFSDTTLFAHGEWRNAVSGRQLPAAFCLRFSRPIIFSSAAIKKLSKIASVQLNVEGSYNLYQYLLNENEECHDLFVRLPGCSTQHYIFDDSMKSSQEDGILRQIPFAHLQDVVFLVSIIRTQLAHNAFFESLVRAHSRSACVDENVVDIHIASSYIDCFDLQFYLKKNFFIARVAVSPSNINVSLECVINGAVLPESQHATAILAKSWSLAVMMRSVLRRGGAISLAALEKPFVMSENVDNNCDVKISQSWLFVPNITDNSINYNKTEHEYVVDERISLNCSCDSNALGRQSPLSLLALFKELEKIEELIPPQKPMNGAQQCTAPPRNEMLAPRTSRIHSENTMTINAFSVLDAICDMAASIDDGESNVSEHSSHSSIVERCSPSTNENQRLRPQIPPQSPSPASERYRASQAGNFSQLSPLDIARQRLAQQAPMSNPTDIFEFDDPPRMNSAGSMGTPAQQFHFPEAGQSPYPFAAVQSTRGPLSAQPTLKRRGRGRKAGNVGDRMLDPARPILDQNTGLMFRGMNIPTRKPRGTSTARRPRRPRKAAHMPASPAHSHQFALNRPMLQRSFSEMPVYPSQMPPVSLSQENRSEASEFDGTEESSDDETDPPPPVCTTAIPQPSSQLTVSSSATVPQTTVVGNLSSSSATLPMVNKCSSLTTASCLPSIPSSAPAAELTPPTSSSPTSTSNSSMQSAALLAHKARKGSLEAVVGKLHCKTAPASSSSSTTSNPYLASDLYDDESEPVSKPPEPVPAKRDSPSLSTSSPGARMSPNLAKMNAEQPGYGSELKIMIKLKQQASTRPSTGPSQSSSGGVPPSMRLVGQPPSSSRSKEEKALLRQKQLKEKNRSAPDERARKAGKRERKGELSSSSSKKLKLDRPLSEQKTATISPKVEFPQALAFASLKNFKIPKVMENEKCESPTPTTTTTPAVATPSSSGAHLNVGQSLSSSTMQVVSSTSLSAATTATTVTATSSSSSAGTSSIFPPKPKSILKSPAEPPPSLFRGMGGMPPMLPGRRPLLPDPRNVMHHPPRPLVALPRMIPSVLSGANFMPPPSSSGRWMALAPQRQPSPRSSPSEQSAPSSGLSETATAMSKMQDSPTEALKIVADEE
Length1391
PositionMiddle
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.434
Instability index66.71
Isoelectric point7.75
Molecular weight151874.06
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07091
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     576.25|      79|      84|     678|     756|       1
---------------------------------------------------------------------------
  678-  752 (122.86/46.81)	...............................PQS..P....SPA.SERYRASQA...GNFSQLSPLDIARQRL.AQQA.....P.......MSNP...TDIFEFDD.......PPR.MNSAGSMGT....PA...........QQFHFPEAGQS.P
  753-  838 (76.38/26.30)	YPFA....................avqstrgPLS..A....QPTlKRRGRGRKA...GNVGD.RMLDPARPIL.DQNTglmfrG.......MNIP...T......R.......KPRgTSTARRPRR....PR...........KAAHMPASPAH.S
  839-  916 (71.29/24.06)	HQFA..........lnrpmlqrsfsempvypSQM..P.....PV.S....LSQE....NRSEASEFDGTEESS.DD..........................ETDP.......PPP.VCTT.AIPQ....PS...........SQLTVSSSATV.P
  917-  960 (35.60/ 8.31)	QT....................................................tvvGNLSSSS......ATL..........P.......M.........................VNKCSSLTTasclPS...........IPSSAPAAELT.P
  961- 1039 (43.62/11.85)	.PTS............................SS..P....TST.SNSSMQSAA.llAHKARKGSLEAVVGKLhCKTA.....PassssstTSNPylaSDL..YDDesepvskPPE........PV....PA...........KR..........D
 1040- 1132 (74.76/25.59)	SPSL..........................sTSS..PgarmSPN.LAKMNAEQP...GYGSELKIM.IKLKQQ.ASTR.....P.......STGP...SQSSSGGV.......PPS.MRLVGQ..P....PSssrskeekallRQKQLKEKNRSaP
 1133- 1228 (64.16/20.91)	DERArkagkrerkgelssssskklkldrplsEQK..T....ATI.SPKVEFPQA...LAFASLKNFKIPK..V.MENE.....K.......CESP...T...............PT.TTTTPAVAT....PS...........SSGAHLNVGQS.L
 1265- 1340 (87.59/31.25)	FPPK...........................PKSilK....SPA.EP..PPSLF...RGMGGMPPMLPGRRPL..................LPDP...RNVMH..H.......PPR.PLVALPRMI....PS.......vlsgANFMPPPSSSG.R
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     174.76|      57|      90|      46|     106|       2
---------------------------------------------------------------------------
   46-  106 (87.30/79.20)	TSLKFSWdYLSQLLRRNLMekRFVLSaDDKEDLMQAA.ADMRKYMPSDSDRDLSTH.LRHL..AE
  140-  200 (87.45/62.76)	TSCSVSW.FGERAVEAQAL..RLYVS.RNRWDLIHTAlTAMFHLVPSDLSRDEKIYcLRSLeyAE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.26|      17|      94|     419|     436|       5
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  419-  436 (26.18/23.95)	SACVDENvVDIHIASSYI
  516-  532 (32.08/23.93)	SENVDNN.CDVKISQSWL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.97|      19|     587|       1|      21|       6
---------------------------------------------------------------------------
    1-   21 (31.10/23.98)	MEK.EDIMerQEQKPVMNSAQC
  583-  602 (31.87/17.90)	LEKiEELI..PPQKPMNGAQQC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07091 with Med1 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVVGKLHCKTAPASSSSSTTSNPYLASDLYDDESEPVSKPPEPVPAKRDSPSLSTSSPGARMSPNLAKMNAEQPGYGSELKIMIKLKQQASTRPSTGPSQSSSGGVPPSMRLVGQPPSSSRSKEEKALLRQKQLKEKNRSAPDERARKAGKRERKGELSSSSSKKLKLDRPLSEQKTATISPKVEF
2) IDDGESNVSEHSSHSSIVERCSPSTNENQRLRPQIPPQSPSPASERYRASQAGNFSQLSPLDIARQRLAQQAPMSNPTDIFEFDDPPRMNSAGSMGTPAQQFHFPEAGQSPYPFAAVQSTRGPLSAQPTLKRRGRGRKAGNVGDRMLDPARPILDQNTGLMFRGMNIPTRKPRGTSTARRPRRPRKAAHMPASPAHSHQFALNRPMLQRSFSEMPVYPSQMPPVSLSQENRSEASEFDGTEESSDDETDPPPPVCTTAIPQPSSQLTVSSSATVPQTTVVGNLSSSS
3) IPPQKPMNGAQQCTAPPRNEMLAPRTSRIH
4) PKVMENEKCESPTPTTTTTPAVATPSSSGAHLNVGQSLSSSTMQVVSSTSLSAATTATTVTATSSSSSAGTSSIFPPKPKSILKSPAEPPPSLFRGMGGMPPMLPGRRPLLPDPRNVMHHPPRPLVALPRMIPSVLSGANFMPPPSSSGRWMALAPQRQPSPRSSPSEQSAPSSGLSETATAMSKMQDSPTEALKIVADEE
5) SIPSSAPAAELTPPTSSSPTSTSNSSMQSAALLAHKARK
991
642
590
1191
948
1176
928
619
1391
986










Molecular Recognition Features






MoRF SequenceStartStop




1) GYGSELKIMIKLKQQAST
2) KEEKALLRQKQLKEKNR
3) LKNFKI
4) LLAHKARK
5) PTEALKIVADEE
6) SKKLKLDRPL
1065
1113
1185
979
1380
1153
1082
1129
1190
986
1391
1162