<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07084

Description Uncharacterized protein
SequenceMEKEDIMERQEQKPVMNSAQCDKYSAVDLSLEEVEEEIRLEKIRQTSLKFSWDYLSQLLRRNLMEKRFVLSADDKEDLMQAAADMRKYMPSDSDRDLSTHLRHLAESLSSDFQAHPGYYKIRNADFSLEITVSLDGQQITSCSVSWFGERAVEAQALRLYVSRNRWDLIHTALTAMFHLVPSDLSRDEKIYCLRSLEYAEKDLLNMSGSAPSIFEQINGGILGLCKPRTESTPFTIYPFVEPVIFLDAASGGIISPTDEQGNSERLLRCILDHPFSDIISEIDTISQLIVSVLYDVEPYLQLCVVSSSTPNFFSDTTLFAHGEWRNAVSGRQLPAAFCLRFSRPIIFSSAAIKKLSKIASVQLNVEGSYNLYQYLLNENEECHDLFVRLPGCSTQHYIFDDSMKSSQEDGILRQILFAHLQDVVFLVSIIRTQLAHNAFFESLVRAHSRSACVDENVVDIHIASSYIDCFDLQFYLKKNFFIARVAVSPSNINVSLECVINGAVLPESQHATAILAKSWSLAVMMRSVLRRGGAISLAALEKPFVMSENVDNNCDVKISQSWLFVPNITDNSINYNKTEHEYVVDERISLNCSCDSNALGRQSPLSLLALFKELEKIEELIPPQKPMNGAQQCTAPPRNEMLAPRTSRIHSENTMTINAFSVLDAICDMAASIDDGESNVSEHSSHSSIVERCSPSTNEASIFFQRLRPQIPPQSPSPASERYRASQAGNFSQLSPLDIARQRLANDGSLFQQQAPMSNPTDIFEFDDPPRMNSAGSMGTPAQQFHFPEAGQSPYPFAAVQSTRGPLSAQPTLKRRGRGRKAGNVGDRMLDPARPILDQNTGLMFRGMNIPTRKPRGTSTARRPRRPRKAAHMPASPAHSHQFALNRPMLQRSFSEMPVYPSQMPPVSLSQENRSEASEFDGTEESSDDETDPPPPVCTTAIPQPSSQLTVSSSAPVPQTTVVGNLSSSSATLPMVNKCSSLTTASCLPSIPSSAPATELTPPTSSSPTSTSNSSMQSAALLAHKARKGSLEAVVGKLHCKTAPASSSSSTTSNPYLASDLYDDESEPVSKPPEPVPAKRDSPSLSTSSPGARMSPNLAKMNAEQSGYGSELKIMIKLKQQASTRPSTGPSQSSSGGVPPSMRLVGQPPSSSRSKEEKALLRQKQLKEKNRSAPDERARKAGKRERKGELSSSSSKKLKLDRPLSEQKTATISPKVEFPQALAFASLKNFKIPKVMENEKCESPTPTTTTTPAVATPSSSGAHLNVGQSLSSSAMQVVSSTSLSAATTATTVTATSSSSSAGTSSIFPPKPKSILKSPAEPPPSLFRGMGGMPPMLPGRRPLLPDPRNVMHHPPRPLVALPRMIPSVLSGANFMPPPSSSGRWMALAPQRQPSPRSSPSEQSAPSSGLSETATAMSKMQDSPTEALKIVADEE
Length1433
PositionMiddle
OrganismBrugia pahangi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.06
Grand average of hydropathy-0.405
Instability index66.58
Isoelectric point6.98
Molecular weight156556.33
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07084
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     658.27|      88|      91|     691|     778|       1
---------------------------------------------------------------------------
  604-  732 (94.34/33.93)	PLSLL....ALFKE..L.EKIEELI..P.PQKP.......MNGA...Q...QCTAPPrnemlaprtsRIHSENTMtinafsvldaicdmaasiddgesnvsehsshssivER..CSPSTNEASIF..FQRLRP.Q...IPPQSPS.......PA.SERYRAS........QAGNFS
  733-  826 (111.28/41.52)	QLSPL....DIARQ.RL.ANDGSLF..Q.QQAP.......MSNP...TDIFEFDDPP..........RMNSAGSM..............................gtpaqQF..HFPEAGQSPYP..FAAVQS.T...RGPLSAQ.......PTlKRRGRGR........KAGNVG
  827-  930 (77.80/26.52)	D.RML....DPARP.ILdQNTGLMF..RgMNIP.......TRKP...RGTSTARRPR..........RPRKAAHM.......................paspahshqfalNRpmLQRSFSEMPVY..PSQMPPvS...LSQENRS.......EA.SEFDGTE........ESSDDE
  931- 1021 (72.28/24.05)	TDPPP....PVCTT.AI.PQPSSQLtvS.SSAP.......VPQT...TVVGNLS...............SSSA................................tlpmvNK..CS.SLTTASCLpsIPSSAP.AtelTPPTSSS.......PT.STSNSSM........QSAAL.
 1022- 1110 (64.58/20.60)	.LA......HKARKgSLeAVVGKLH..C.KTAPassssstTSNPylaSDLY..DDES..........EPVSKPPE...............................pvpaKR..DSPSLSTSS................PGARMS.......PN.LAKMNAE........QSGYGS
 1111- 1225 (63.13/19.95)	ELKIMiklkQQAST.RP.STGPS......QSSS.......GGVP...PSMRLVGQPP..........SSSRSKEE.......................kallrqkqlkekNR..SAPDERARKA...GKRERK.G...ELSSSSSkklkldrPL.SEQKTATispkvefpQALAFA
 1226- 1331 (71.60/23.74)	SLKNF....KIPK..VM.ENEKCES..P.TPTT.......TTTP...AVATPSSSGA..........HLNVGQSL...........sssamqvvsstslsaattattvtaTS..SSSSAGTSSIF..PPK..P.K...SILKSPA......ePP.PSLFR.G........MGG...
 1332- 1406 (103.26/37.93)	.MPPM....LPGRR.PL.LPDPRNV..M.HHPP.........RP...LVALPRMIPS..........VLSGANFM...................................P....PPSS...SGR..WMALAP.Q......RQPS.......PR.SS..PSE........QSAPSS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.71|      22|      95|      85|     106|       2
---------------------------------------------------------------------------
   85-  106 (41.92/26.34)	MRKYMPSDSDRDLSTH.LRHL..AE
  176-  200 (30.78/17.25)	MFHLVPSDLSRDEKIYcLRSLeyAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.49|      41|      96|     424|     467|       3
---------------------------------------------------------------------------
  424-  467 (59.63/44.84)	VFLVSIIRTQLAHNafFESLVRAHSRSACVDENvVDIHIASSYI
  523-  563 (70.86/42.52)	VMMRSVLRRGGAIS..LAALEKPFVMSENVDNN.CDVKISQSWL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.55|      22|      95|      28|      52|       4
---------------------------------------------------------------------------
   28-   52 (32.64/27.29)	DLSLEEVeeeIRLEKIRQTSLKFSW
  125-  146 (39.91/25.04)	DFSLEIT...VSLDGQQITSCSVSW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.63|      21|      74|     279|     300|       5
---------------------------------------------------------------------------
  279-  300 (29.97/28.23)	ISEIDTIsQLIVSVLYDVEPYL
  355-  375 (34.65/27.15)	LSKIASV.QLNVEGSYNLYQYL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07084 with Med1 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVVGKLHCKTAPASSSSSTTSNPYLASDLYDDESEPVSKPPEPVPAKRDSPSLSTSSPGARMSPNLAKMNAEQSGYGSELKIMIKLKQQASTRPSTGPSQSSSGGVPPSMRLVGQPPSSSRSKEEKALLRQKQLKEKNRSAPDERARKAGKRERKGELSSSSSKKLKLDRPLSEQKTATISPKVEF
2) IPPQKPMNGAQQCTAPPRNEMLAPRTSRIH
3) PKVMENEKCESPTPTTTTTPAVATPSSSGAHLNVGQSLSSSAMQVVSSTSLSAATTATTVTATSSSSSAGTSSIFPPKPKSILKSPAEPPPSLFRGMGGMPPMLPGRRPLLPDPRNVMHHPPRPLVALPRMIPSVLSGANFMPPPSSSGRWMALAPQRQPSPRSSPSEQSAPSSGLSETATAMSKMQDSPTEALKIVADEE
4) QRLANDGSLFQQQAPMSNPTDIFEFDDPPRMNSAGSMGTPAQQFHFPEAGQSPYPFAAVQSTRGPLSAQPTLKRRGRGRKAGNVGDRMLDPARPILDQNTGLMFRGMNIPTRKPRGTSTARRPRRPRKAAHMPASPAHSHQFALNRPMLQRSFSEMPVYPSQMPPVSLSQENRSEASEFDGTEESSDDETDPPPPVCTTAIPQPSSQLTVSSSAPVPQTTVVGNLSSSS
5) SIFFQRLRPQIPPQSPSPASERYRASQAGNFS
6) SIPSSAPATELTPPTSSSPTSTSNSSMQSAALLAHKARK
1033
621
1233
742
701
990
1218
650
1433
970
732
1028










Molecular Recognition Features






MoRF SequenceStartStop




1) GYGSELKIMIKLKQQAST
2) KEEKALLRQKQLKEKNR
3) LAHKARK
4) LKNFKI
5) PTEALKIVADEE
6) SKKLKLDRPL
1107
1155
1022
1227
1422
1195
1124
1171
1028
1232
1433
1204