<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07083

Description Uncharacterized protein
SequenceMYEQNEEKEDDSKTTESNEETKTRQQKNAAKKARQFSFETMFTEVMQGALTRTTETFGKEGVKKTADDDKRFHREQSKSIREHHYAFDEFVSSSLSKPAGTSVEDLESDDDFGEFFVPLPEGFVPDKEIFETKKTTGCDGDDDEFDDLDDGVPVVDLIPAASEAQLRHGKKPVSALAFDHQGTKFASGGYDYTVNLFEFQKMDLSLRSSRELMPCESHIINGLAFSSNGEKLLVASGHAQIRILDRQGKQWAETVRGDQYLVDLSNTKGHSGSVNSCCWHPVVKTEFLSCANDGTLRIWSTDDYKEITHCINKQRKVIKTKSASGKRTIPTTCCYSRDGKYIAAGCDDGSIQIWKHGNLYVSVNTAYLNRTAHTASVTSLQFSPNNTKKHFAVDGTLKLWQLEAFDKPCHIVEDLKNEFISTDCGFAPHGEMVYTGTSFDDKNGSDGVLAFFDSKSFDLIYRITYPNLSCIRISWQPKINQILVGLSDGSLRLYYDPVSSLRGALLCVSRPLRRARQQEVIREELVLSPLTLEMFQPRGEEGEEKEVTTWRLKKYLRMMDNRLRPDFRKPADMPMSGPSSGGRVAASGGTLHSYIAKQVGTKRNRDFLADTDVRASILRHAEEAEKNPYYVTKAYLKNQPVTIFQEKTTAPEEEEEADKELEPLYKISKNKTSLRNILYLSLQFNKLCVNFSFPTLSKKCYGFVEYKYVGNVMIDYQFKEELIKTRERVEDLYSFEDQFIGVFSQVGRGTYGHVYKAQPRHPEQIPGNGAKEFALKLIEGQGFSMSACREIALLRELKHPNLIKLQRVFLTTDRKVWLLFDYAEHDLWHIIKFHRAAKQKKQPVLVPKGMVKSLLYQILDGIHYLHSNWILHRDLKPANILVMGEGPGVERGRVKIGDMGFARIFHNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDIWAIGCIFAELLTSEPVFFCREEDIKASSPYHQDQLNRIFTVMGYPSESDWQDLKKMPEYQKLTQDFKRANYANCTLQRYMDKHKIKADTRSFSLLQRLLTMDPIKRVTAQDAMDDAYFKEDPRPTADVFSGCDIPYPKREFLSDENDDKSASASKPQQVQPPQQSQQQPIGMHPQQSVMEPAAKKMRMQQGPQIPTTQQMESMINAPTSGMFVTSGAQDYPPVGSGPAISSKGGMPFEQHSQQQIMQSQHINSGMQQMSYGHQQQHQIINQGPNIYQQQQIGMNQQIAGPPQGQMTQRSVQMSAQSSVLQSSYQQQMVQPGMISSQQMMGSGNGMLGQQGSMTGPMGGPQTQMGPPQGQMGPQGPTIMQQMRPQMSYVDQNGRVIQSGGIIIQPGQEMMPQQGHYMIQQQQWPQMQPRF
Length1361
PositionKinase
OrganismBrugia pahangi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.09
Grand average of hydropathy-0.611
Instability index48.60
Isoelectric point6.86
Molecular weight154205.13
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07083
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.54|      29|      35|    1002|    1035|       1
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 1002- 1035 (48.93/43.11)	QK.LTQD.FKRanyanCTLQRYMDKHKIKADTRS....FS
 1038- 1072 (40.61/24.48)	QRlLTMDpIKR.....VTAQDAMDDAYFKEDPRPtadvFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     286.65|      39|      52|    1176|    1214|       2
---------------------------------------------------------------------------
 1099- 1123 (30.24/10.04)	.......Q.QV.QPPQQSQQQPIG..................mH...PQQSVMEP
 1155- 1190 (46.14/19.43)	..VTSGAQ.DYpPVG..SGPAISSKG.G.........MPFEQ.H...SQQQIMQS
 1191- 1226 (65.98/31.16)	QHINSGMQ.QM.SYGHQQQHQIINQG.P.........NIYQ.......QQQIGMN
 1227- 1262 (48.25/20.68)	QQIAGPPQgQM.T...QRSVQMSAQS.S.........V.LQS.S...YQQQMVQP
 1263- 1288 (30.78/10.35)	GMISS..............QQMMGSGnG.........MLGQQ.G...SMTGPM..
 1289- 1311 (30.15/ 9.98)	.....GGP.QT.QMG.PPQGQMGPQG.P......................TIMQ.
 1312- 1357 (35.12/12.92)	.Q....MRpQM.SYV.DQNGRVIQSG.GiiiqpgqemMPQQG.HymiQQQQWPQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     186.11|      48|      48|     140|     187|       3
---------------------------------------------------------------------------
   87-  143 (59.59/38.38)	.FDEFvssslskPAGT.SVEDLESDDDFGEffvpLPEGFVPDKEI.FETKKTTG..CDGDDD
  144-  191 (83.05/56.75)	EFDDL.......DDGV.PVVDLIPAASEAQ....LRHGKKPVSALAFDHQGTKF..ASGGYD
  198-  236 (43.47/25.77)	EFQKM.......DLSLrSSRELMPCES.........H...IINGLAFSSNGEKLlvAS....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.31|      14|      47|     693|     707|       4
---------------------------------------------------------------------------
  693-  707 (23.77/18.38)	FPTLSKKCYGFVeYK
  743-  756 (27.54/16.41)	FSQVGRGTYGHV.YK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.43|      36|      53|     267|     304|       5
---------------------------------------------------------------------------
  267-  303 (67.19/42.20)	TKGHSG..SVNS.CCWHPVVKTEFLSCaNDGTLRIWSTDD
  320-  358 (60.24/31.01)	TKSASGkrTIPTtCCYSRDGKYIAAGC.DDGSIQIWKHGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.89|      35|     202|     564|     641|       8
---------------------------------------------------------------------------
  604-  641 (51.65/108.54)	NRDFLAdTDVRASILrhAEEAEKNPYYVTK....AYLKNQPV
  806-  844 (59.24/22.98)	QRVFLT.TDRKVWLL..FDYAEHDLWHIIKfhraAKQKKQPV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07083 with CDK8 domain of Kingdom Metazoa
Unable to open file!