<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07050

Description Uncharacterized protein
SequenceMDATNGQKPHVGQPSPGGGSASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGPPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSHGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGILAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDALNSDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLIASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISMLKCRLYGMSMTTNVEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGGKDQTGQNASGTASGMPDFTNGETKIKQEPSLNNGNNGCMGGRQTQQQQLSANRSELQQQQQQQQQSFLDAGTENSIGFPSYSGQSDTTTMTMSTTGTNSTSTSMLNPLQLGALLGQAKNSLTSNSNTNERGKKTRKRKTGTDGLWRSPKRKSDGGDNNTATEILLESSSSENSTPLGTPTSRENLAETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSSTEQQQQQQPQQEVEELIKMRESSSTRKSKKNRSSGGSEEKKSSPTNIFVDETSTTSSGNKGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTSSPKTGSLTSATEDRQRSERKSGGGKSSSSSSKSSSEDTKSGGNKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGSAGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCGKPVQSPKHSPVYGSSPKHNAPNVSVVPMSVPMSLSVSTVPNTVGNVPSVAVSVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGSGHQSPKTKSSSSKMKQLEMISPGSEATQVSSLQASGGSTPPSGQVDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDACGNGGGNVKGSGSSGLSSTGGMSSAGQKEKNIGGSGSSSSSGGKTIGEGGKSCVTKNASIDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSSNVITGNNGSPKTHTGLKPGVNSGPASKKPQTLQATQKMLPTKMMLAAAGMKSAISSSGATNTGTGAGITASATGGIGGNPLSKSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISNLPPSLPPQLMMEGLMKQLDTKFQIPKLSARANVADADKNKSSDKLSILPDSTKQTLDGLKQEQSKIAGLSNITVSVSKSSQPDDQSRRDHSQNKPDNLSITTSAAGAISLNLVGENTGLMLPPQSTADSDVPTNLCIQPMVDNESSRDSCKDLGMRQTSTGQQFLGKIDDTNVGGILSKSNVSDQLTSSGAKSYGTMTSSNTSTASSGAIVAESLNLSTKPADQAVLQTKYNKITVEEKKQQQTSSASLSSSSSSSSSSSSSLIFSSLASVATSSDGNPVMTSDSGGGGGSNGSGEQEVAAAAAAAEMLLDFSAANKDSMTKGSHGLPVSLTQHHLTTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length1997
PositionMiddle
OrganismAtta cephalotes (Leafcutter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.03
Grand average of hydropathy-0.561
Instability index57.66
Isoelectric point9.21
Molecular weight208718.71
Publications
PubMed=21347285

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07050
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|    1135.63|     181|     229|    1026|    1219|       2
---------------------------------------------------------------------------
  809-  901 (90.01/21.29)	.............................................................K.......................MR.............ESSST.................RKSKKNR.................SSGGS......EEKK....S...SP..TNI...FVDE..TSTTSS................GNK.......G........LP..V....P...........PSVSITPISCGnLDQASTTNY...N............................SVltGmgleR.RPGIE.I...IP.IASSP
  976- 1130 (214.71/61.57)	..GPMGPP...DKVPSGG...........KQQ.QDPL............................................................................................skpvsvsikpstEQSPPSGGSA..GVGLSCSS....SRPTSP..AAVRK.FSPS..PTHSSSLATLV.GKSSPTL.KAGQSAA.ATC.GKPVQSPKHSP..VYGSSPKHNA.......PNVSVVPMSVP.MSLSVSTVP...N............................TV..G....N.VPSVA.VSVPVP.ASASP
 1131- 1295 (199.55/56.67)	KHGNTSSPKHGSSAASSG...........KPS.MSALKSAANSpssksssssssdsATTPSK.......................VK.............SSSSSSS..........KDSSGRGDKDRR............TSSVSSSGGS..GSGHQSPK....TKSSSSkmKQLEM.ISPGseATQVSSLQASG.GSTPPS....GQVDA.AS..........KSA..IAAQQARNRK.......SSLN....AVI.DKLKNAQ........................................................H.CTETD
 1296- 1424 (144.88/39.02)	ACGNGGGNVKGS..GSSG...........LSS.TGGM...............................................................SSAGQKE..........KNIGGSG..................SS.SSSGGKtiGEGGKS...............CVTK.NASI..DTKNPG.EYMV.KHSSDGI.KITINKT.RTKdSKQAANLKLS......SSGSMAA.......TSSSSSLSSVA.SSSSSSSSS...N............................VI...........................
 1425- 1616 (166.47/45.99)	.TGNNGSPK.....THTG..................LKPGVNS...............GPASkkpqtlqatqkmlptkmmlaaagMK.............SAISSSG..........ATNTGTGA................GITASATGGI..G...........GNPLSK..SSSSK.ASGS..PKTSSGVTDLSrGRDKPRIsKSGDKGIfASK.GLG.DARKSSPsaLREESESERAfkllaahASISNLPPSLP.PQLMMEGLMkqlD............................TK..F....Q.IPKLS.ARANV..ADADK
 1617- 1770 (128.63/33.77)	...NKSSDKL.SILPDST...........KQT.LDGLK...............................................................................QEQSKIAGLSNI............TVSVSKS..S..QPDDQSRRdhsqNKPDN......LS.ITTS..AAGAISL.NLV.GENTGLM..............LPPQSTADSD..V....P...........TNLCIQPM...........VD...NessrdsckdlgmrqtstgqqflgkiddtNV..G....G.ILSKSnVSDQLT.SSGAK
 1771- 1980 (191.39/54.04)	SYGTMTS..SNTSTASSGaivaeslnlstKPAdQAVLQTKYNK.............ITVEEK.......................KQqqtssaslsssssSSSSSSSslifsslasvATSS.....DGN............PVMTSDSGGG..GGSNGSGE...qEVAAAA..AAAEMlLDFS..AANKDSMTK...GSHGLPV.SLTQHHL.TTI.PERAMTQAAPT..VRRNTPPPPP.......PP.PPLPAPFP.PAASPSVSV...H............................IV..K....SpAPSPR.VIPPSPhSSASP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     180.66|      50|     174|     733|     782|       3
---------------------------------------------------------------------------
  467-  497 (25.60/ 7.04)	.........................M.ATAELDLTDISMLKCRLYGMSmttNV......EQTS
  513-  541 (25.54/ 7.01)	TMRMLlkiWEGR.SLPAVMNSLTSGS.GSSN................................
  545-  596 (46.12/19.04)	...NLnlgSGGKDQTGQNASGTASGMpDFTNGET.....KIKQEPSLN...NGnngcmgGRQT
  733-  782 (83.40/40.84)	SRENL...AETRTSTPTSATSLTSGM.DFSNLDTTDILDKSASDYDLD...NS......EKDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.57|      14|     183|     604|     617|       5
---------------------------------------------------------------------------
  604-  617 (27.02/16.54)	NRSELQQQQQQQQQ
  788-  801 (27.55/17.02)	QHSSTEQQQQQQPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.98|      15|      17|     682|     696|       6
---------------------------------------------------------------------------
  682-  696 (25.41/14.48)	RGKKTR....KRKTGTDGL
  698-  716 (19.56/ 9.38)	RSPKRKsdggDNNTATEIL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07050 with Med1 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQHCTETDACGNGGGNVKGSGSSGLSSTGGMSSAGQKEKNIGGSGSSSSSGGKTIGEGGKSCVTKNASIDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSSNVITGNNGSPKTHTGLKPGVNSGPASKKPQTLQATQKMLPTKMMLAAAGMKSAISSSGATNTGTGAGITASATGGIGGNPLSKSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESE
2) LDFSAANKDSMTKGSHGLPVSLTQHHLTTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
3) LVGENTGLMLPPQSTADSDVPTNLCIQPMVDNESSRDSCKDLGMRQTSTGQQFLGK
4) PKLSARANVADADKNKSSDKLSILPDSTKQTLDGLKQEQS
5) SNITVSVSKSSQPDDQSRRDHSQNKPDNLSIT
6) SSNGSYNLNLGSGGKDQTGQNASGTASGMPDFTNGETKIKQEPSLNNGNNGCMGGRQTQQQQLSANRSELQQQQQQQQQSFLDAGTENSIGFPSYSGQSDTTTMTMSTTGTNSTSTSMLNPLQLGALLGQAKNSLTSNSNTNERGKKTRKRKTGTDGLWRSPKRKSDGGDNNTATEILLESSSSENSTPLGTPTSRENLAETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSSTEQQQQQQPQQEVEELIKMRESSSTRKSKKNRSSGGSEEKKSSPTNIFVDETSTTSSGNKGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTSSPKTGSLTSATEDRQRSERKSGGGKSSSSSSKSSSEDTKSGGNKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGSAGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCGKPVQSPKHSPVYGSSPKHNAPNVSVVPMSVPMSLSVSTVPNTVGNVPSVAVSVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGSGHQSPKTKSSSSKMKQLEMISPGSEATQVSSLQASGGSTPPSGQVDAASKSAIAAQQARNRKSSLNAVIDKL
7) TSSDGNPVMTSDSGGGGGSNGSGEQEVAAAAAAAEM
1288
1888
1690
1603
1648
539
1851
1564
1997
1745
1642
1679
1285
1886










Molecular Recognition Features






MoRF SequenceStartStop




1) KGKEWQMEFL
2) RAFKLLAAH
3) SKMKQLEMIS
4) TLQATQKMLPTKMMLAAAGMK
24
1565
1225
1452
33
1573
1234
1472