<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07050

Description Uncharacterized protein
SequenceMDATNGQKPHVGQPSPGGGSASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGPPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSHGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGILAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDALNSDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLIASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISMLKCRLYGMSMTTNVEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGGKDQTGQNASGTASGMPDFTNGETKIKQEPSLNNGNNGCMGGRQTQQQQLSANRSELQQQQQQQQQSFLDAGTENSIGFPSYSGQSDTTTMTMSTTGTNSTSTSMLNPLQLGALLGQAKNSLTSNSNTNERGKKTRKRKTGTDGLWRSPKRKSDGGDNNTATEILLESSSSENSTPLGTPTSRENLAETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSSTEQQQQQQPQQEVEELIKMRESSSTRKSKKNRSSGGSEEKKSSPTNIFVDETSTTSSGNKGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTSSPKTGSLTSATEDRQRSERKSGGGKSSSSSSKSSSEDTKSGGNKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGSAGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCGKPVQSPKHSPVYGSSPKHNAPNVSVVPMSVPMSLSVSTVPNTVGNVPSVAVSVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGSGHQSPKTKSSSSKMKQLEMISPGSEATQVSSLQASGGSTPPSGQVDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDACGNGGGNVKGSGSSGLSSTGGMSSAGQKEKNIGGSGSSSSSGGKTIGEGGKSCVTKNASIDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSSNVITGNNGSPKTHTGLKPGVNSGPASKKPQTLQATQKMLPTKMMLAAAGMKSAISSSGATNTGTGAGITASATGGIGGNPLSKSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISNLPPSLPPQLMMEGLMKQLDTKFQIPKLSARANVADADKNKSSDKLSILPDSTKQTLDGLKQEQSKIAGLSNITVSVSKSSQPDDQSRRDHSQNKPDNLSITTSAAGAISLNLVGENTGLMLPPQSTADSDVPTNLCIQPMVDNESSRDSCKDLGMRQTSTGQQFLGKIDDTNVGGILSKSNVSDQLTSSGAKSYGTMTSSNTSTASSGAIVAESLNLSTKPADQAVLQTKYNKITVEEKKQQQTSSASLSSSSSSSSSSSSSLIFSSLASVATSSDGNPVMTSDSGGGGGSNGSGEQEVAAAAAAAEMLLDFSAANKDSMTKGSHGLPVSLTQHHLTTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length1997
PositionMiddle
OrganismAtta cephalotes (Leafcutter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.03
Grand average of hydropathy-0.561
Instability index57.66
Isoelectric point9.21
Molecular weight208718.71
Publications
PubMed=21347285

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07050
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|    1135.63|     181|     229|    1026|    1219|       2
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  809-  901 (90.01/21.29)	.............................................................K.......................MR.............ESSST.................RKSKKNR.................SSGGS......EEKK....S...SP..TNI...FVDE..TSTTSS................GNK.......G........LP..V....P...........PSVSITPISCGnLDQASTTNY...N............................SVltGmgleR.RPGIE.I...IP.IASSP
  976- 1130 (214.71/61.57)	..GPMGPP...DKVPSGG...........KQQ.QDPL............................................................................................skpvsvsikpstEQSPPSGGSA..GVGLSCSS....SRPTSP..AAVRK.FSPS..PTHSSSLATLV.GKSSPTL.KAGQSAA.ATC.GKPVQSPKHSP..VYGSSPKHNA.......PNVSVVPMSVP.MSLSVSTVP...N............................TV..G....N.VPSVA.VSVPVP.ASASP
 1131- 1295 (199.55/56.67)	KHGNTSSPKHGSSAASSG...........KPS.MSALKSAANSpssksssssssdsATTPSK.......................VK.............SSSSSSS..........KDSSGRGDKDRR............TSSVSSSGGS..GSGHQSPK....TKSSSSkmKQLEM.ISPGseATQVSSLQASG.GSTPPS....GQVDA.AS..........KSA..IAAQQARNRK.......SSLN....AVI.DKLKNAQ........................................................H.CTETD
 1296- 1424 (144.88/39.02)	ACGNGGGNVKGS..GSSG...........LSS.TGGM...............................................................SSAGQKE..........KNIGGSG..................SS.SSSGGKtiGEGGKS...............CVTK.NASI..DTKNPG.EYMV.KHSSDGI.KITINKT.RTKdSKQAANLKLS......SSGSMAA.......TSSSSSLSSVA.SSSSSSSSS...N............................VI...........................
 1425- 1616 (166.47/45.99)	.TGNNGSPK.....THTG..................LKPGVNS...............GPASkkpqtlqatqkmlptkmmlaaagMK.............SAISSSG..........ATNTGTGA................GITASATGGI..G...........GNPLSK..SSSSK.ASGS..PKTSSGVTDLSrGRDKPRIsKSGDKGIfASK.GLG.DARKSSPsaLREESESERAfkllaahASISNLPPSLP.PQLMMEGLMkqlD............................TK..F....Q.IPKLS.ARANV..ADADK
 1617- 1770 (128.63/33.77)	...NKSSDKL.SILPDST...........KQT.LDGLK...............................................................................QEQSKIAGLSNI............TVSVSKS..S..QPDDQSRRdhsqNKPDN......LS.ITTS..AAGAISL.NLV.GENTGLM..............LPPQSTADSD..V....P...........TNLCIQPM...........VD...NessrdsckdlgmrqtstgqqflgkiddtNV..G....G.ILSKSnVSDQLT.SSGAK
 1771- 1980 (191.39/54.04)	SYGTMTS..SNTSTASSGaivaeslnlstKPAdQAVLQTKYNK.............ITVEEK.......................KQqqtssaslsssssSSSSSSSslifsslasvATSS.....DGN............PVMTSDSGGG..GGSNGSGE...qEVAAAA..AAAEMlLDFS..AANKDSMTK...GSHGLPV.SLTQHHL.TTI.PERAMTQAAPT..VRRNTPPPPP.......PP.PPLPAPFP.PAASPSVSV...H............................IV..K....SpAPSPR.VIPPSPhSSASP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     180.66|      50|     174|     733|     782|       3
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  467-  497 (25.60/ 7.04)	.........................M.ATAELDLTDISMLKCRLYGMSmttNV......EQTS
  513-  541 (25.54/ 7.01)	TMRMLlkiWEGR.SLPAVMNSLTSGS.GSSN................................
  545-  596 (46.12/19.04)	...NLnlgSGGKDQTGQNASGTASGMpDFTNGET.....KIKQEPSLN...NGnngcmgGRQT
  733-  782 (83.40/40.84)	SRENL...AETRTSTPTSATSLTSGM.DFSNLDTTDILDKSASDYDLD...NS......EKDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.57|      14|     183|     604|     617|       5
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  604-  617 (27.02/16.54)	NRSELQQQQQQQQQ
  788-  801 (27.55/17.02)	QHSSTEQQQQQQPQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.98|      15|      17|     682|     696|       6
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  682-  696 (25.41/14.48)	RGKKTR....KRKTGTDGL
  698-  716 (19.56/ 9.38)	RSPKRKsdggDNNTATEIL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07050 with Med1 domain of Kingdom Metazoa
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