<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07044
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MNRLDDPPGLMKGRKPSFIGMNGAPETDDQQRVRFQVELEFVQCLANPNYLNFLAQRGYFKDMTFINYLKYLLYWKEPEYAKYLKYPMCLYFLDLLQYEHFRREVVNSQCTKFIDDQQILLWQHYTRRRTRLLQTAAEQTQHTNSQNNGIVQPKVP |
Length | 156 |
Position | Middle |
Organism | Atta cephalotes (Leafcutter ant) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea>
Formicidae> Myrmicinae> Atta.
|
Aromaticity | 0.14 |
Grand average of hydropathy | -0.675 |
Instability index | 37.38 |
Isoelectric point | 8.94 |
Molecular weight | 18784.32 |
Publications | PubMed=21347285
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07044
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 87.82| 22| 44| 39| 61| 1
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39- 61 (35.68/20.29) LEFVQCLANPNYLNFLaQRGYFK
69- 84 (21.94/ 7.96) LKYLLYWKEPEYAKYL.......
85- 102 (30.20/13.29) .KYPMCL...YFLDLL.QYEHFR
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|