<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07032

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMCNLLTSAMETKVTSKTSSLKALLLRAWRERWSDLQWGINIKTILPRGVSGDVYNLADCILQQALVGLGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCILSLLEFLESIQIGITCRGKPEEDLLAAAVLSIVNWLLQCYLHTVTKMPQSSPLTPQPTELMDKPASILKQMLNSDFLCAMMYLAKYDDKDLYIEVVKKCQEIEALLKTSSLKSSVPIEDSLKKLCNLEVECLALSSEMTQMESITHCLQPLFAVQVLLNPSTETAVFVNQLLMVQRLKNYTNSRLYCEIIRACLMCLHNVTGTFKESQWGAFTFLKVPLILKELHVAHSNGDEKSEYSQDILDAFELLLQFTPLLDIMDTACSCNSVECLLNALQKVNLVTEKQAKQLSGRREGVTATLQKLESSTSTPSIPKVIVRAEPTLSGILKTLNADYTKIHEALLSMLYQVLTGKSFELMLAVATVEGKLKTFVTKLIKFNECSKQINEPVPPKTAATRAMLFDVSFLMLCSIVQTYGSDAVLEEGGGDSFFEQWVRECMPERNQPKSPQKMLQNIDPARVDALLAQINSPDPDFKSSNIKWHIACQSAMGAVKELLCAWESDVLGAGDVKRALDGLRATACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLPGDEMQDNLKERSSLMSQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLETVWTTVNQRGWINIQATQSLESLLNTGGSLWFVSNIVKEVLKYRYQEELDQAVDLAFAIFHLDIENCTLDLINHIIPQYLYNSLQSEELVEPQSSVLAKLCVYCIFSTLEYNNSNPYRGNSRKRVRRDLDAEELDALSVPANKILRLNESGDSNPIFGSQSPQAQGPTNGQKSVVLRDPLLSSLNGLFTIFTFLAGRDGEVSQQTHFILQFLRLMVQCVPCLLKALPELFTTDILLRFYDIQTAAGRKATARDLCMLRNITLKPTK
Length983
PositionTail
OrganismDufourea novaeangliae (Sweat bee)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Halictidae> Rophitinae> Dufourea.
Aromaticity0.07
Grand average of hydropathy-0.010
Instability index52.12
Isoelectric point6.33
Molecular weight110100.74
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07032
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.55|      68|     279|     362|     446|       1
---------------------------------------------------------------------------
  374-  446 (103.48/73.61)	SVECLLNALQkvnlvTEKQAKQLSGRREGVTATLQKLESSTSTP..SIPKVIVRAEPTLS..GILKTLNADYTKIHE
  654-  725 (105.06/64.25)	MVQHFLTPLP.....GDEMQDNLKERSSLMSQIIRKMQYDVHPPtqSKTKVLSMSHSIISrqPILEQLETVWTTVNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.47|      10|      37|     827|     836|      11
---------------------------------------------------------------------------
  827-  836 (20.81/12.28)	EYNNSNPYRG
  866-  875 (19.66/11.25)	ESGDSNPIFG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07032 with Med24 domain of Kingdom Metazoa
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