<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07030

Description ATP-dependent DNA helicase RecQ family protein
SequenceMSTEIENNYKSNLERFQQSKLTPFGLDEIVYNTYKPTKTFQIENNLNHKPYKSIDNLFNISYKLPPTTTSQSNTSSSTYIPASTYTNSKKSPDYNNKTTFSNNKSTSPKNTPMSDNMADNFTLSDNEISPPPQRSNSSNGINSFSSNNNKSSNYISSNPPQYTRSTLSTDSSTTSSSRNSLHEEINSIKIKLFDLDRLKKKLKKEDTQSEEDALRNFREKKATIQEIEQLTSQLQALEKSLESGGSNHQPSSSNFTSNAYSSSTFSTSGNTSFISSNNNSSRNTNSTLSTTKSFNTPNSAPKRFDDDMIFENDGNDKEDIPEPITSNYKSVNGTKSNSTSNTNSYRTHEDSEIITNDVPYIFNDSDESNGGVIDIDQEDLFFEEPKTTTTSTKTSSFSTSTSTSFSTLTKSNSNIQFTPTVTDTSKFGGNNFPWYEQIEICNKTMFGNKSWRLNQKEIINAALDGNDVFVLMPTGGGKSLCYQIPAYCQEGLTIVISPLISLIQDQVQFLQSIDYPAAALSSSVSSDEVSRIYKDLNRHDGPQIKLLYLTPEKVAQSDTIMNIFRTLHSKGRFSRVVIDESHCISSWGHDFRPDYKSLGTLKKNFPDLPIMALTATATERVKSDVIYNLGMKNPVCFKQSFNRPNLSYFVLPKKKETVQNIVTFINKNYPGKSGIIYCFSCYECETVAANLKSLGISAQYYHGKMDTNDRATVQEKWTRDRVKVICATIAFGMGINKPDVRFVIHYTLPKSLEGYYQESGRAGRDGLPSHCLLYYNYADKHKIDDMIQNSAQELGTTMNIRENRESLNKMVSYCENRIDCRRVLQLSHFNENFDKNQCNQTCDNCQCTDTFTNKDVTEEAKNIIYIVNNTENMTVNMIIDVVKGSKNKKIIQKGQDKLKYYGFGKSMDKLDIERIIRELVSRNILKEHIQPTSYKPICYIVLGNKMNQFTSGQMKLVLSFRSSTSANNASKKKSTSSLSDSGSSSIVNMPNIVPIAKNTSLSKEELLSALHDCRAEIADENNIIPYHIATENALNDLADKKPQTLEELRGISTFTKIKIEKYGQQFIDCIKNFLNPSSSKSTKKSSSSSSTKKPSILEDDEDFKMDTTATSTIDLDDNYQFDVEEEDIPTSVMPLTSSHYFNKNSNNNKRKLDDPDENPKPIKQTKSKSTK
Length1171
PositionUnknown
OrganismTieghemostelium lacteum
KingdomAmoebozoa
LineageEukaryota> Amoebozoa> Evosea> Eumycetozoa> Dictyostelia> Dictyosteliales> Raperosteliaceae> Tieghemostelium.
Aromaticity0.08
Grand average of hydropathy-0.745
Instability index44.79
Isoelectric point7.45
Molecular weight131833.29
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07030
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     389.27|      93|      93|     583|     675|       1
---------------------------------------------------------------------------
  583-  675 (157.24/103.01)	CISSW.GH.D.......FRPDYKSLGT...LKKNFPDLPIMALTATATERVKSDVIYNLGMKNPVCFKQSFNRPNLSY...FVLPKKKETVQNIVTFINKNYPGKSGI
  678-  767 (131.52/84.85)	CFSCYeCE.T.......VAANLKSLGI...SAQYYHGKMDTNDRATVQEKWTRDRVKV..ICATIAFGMGINKPDVRFvihYTLPKSLEGY.....YQESGRAGRDGL
  771-  855 (100.51/62.94)	CLLYY.NYaDkhkiddmIQNSAQELGTtmnIRENRESLNKM..VSYCENRIDCRRVLQLSH.....FNENFDKNQCN........QTCDNCQCTDTFTNKD.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     314.29|      54|      57|     267|     320|       2
---------------------------------------------------------------------------
   74-  123 (47.81/15.42)	...................TSSST.YIpaSTYTNSKKspdyN.........NKTTFSN.NKS........TSPKNTP..MSDN.............M......ADNF...............TL
  124-  197 (49.93/16.43)	S....DNEIS.pppqrsnsSNGINSF...SSNNNKSS....NyissnppqyTRSTLST.DSS.........TTSSSRNSLHEE.............InsikikLFDL...............DR
  269-  314 (74.11/27.99)	.....................GNTSFI..SSNNNSSR....N.........TNSTLST.TKS.....F..NTPNSAPKRFDDD.............M......IFEN...............DG
  315-  370 (67.22/24.70)	N....DKEDI.....pepiTSNYKSVN..GTKSNSTS....N.........TNSYRTH.EDS.....E..IITNDVPYIFNDS.............D........ES...............NG
  371-  465 (29.40/ 6.62)	GvidiDQEDLffeepktttTSTKTSSF..STS...................TSTSFSTlTKSnsniqF..TPTVTDTSKFGGNnfpwyeqieicnkT......MFGNkswrlnqkeiinaalDG
 1077- 1123 (45.81/14.47)	....................SSSKSTK..KSSSSSST....K.........KPSILED.DED.....FkmDTTATSTIDLDDN.....................YQF...............DV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.89|      20|     897|      26|      73|       3
---------------------------------------------------------------------------
    4-   23 (37.77/30.00)	EIENN.....YKSNLERFQQS.KLTP
   41-   66 (28.12/25.06)	QIENNlnhkpYKSIDNLFNISyKLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.81|      18|     682|     208|     234|       4
---------------------------------------------------------------------------
  211-  230 (25.53/26.60)	EDALRNFREKKAtiQEIEQL
 1031- 1048 (30.27/ 7.82)	ENALNDLADKKP..QTLEEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07030 with Med34 domain of Kingdom Amoebozoa
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