<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07017
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MIENTIAQKPSKLSSTEHAQLTELLVAKDNELKATLKRAAEQAKINLKMEALKAEVERQDQDIQQLQRQLKEAEQILATAIYQAKQKLQSIARANKRPVPSEELIKYAHRISATNAICAPLTWQQGDPRRPYPTDLEMRVGFLGRLSDPSNLPLNGQLLGSHLGVPSDLHRAGHPAGEPPVSQSNQFAWHPSGEIHMSVGGQGSVAVNTHKQETEDVEVMSTDSSSSSSSDSQ |
Length | 233 |
Position | Middle |
Organism | Trachymyrmex zeteki |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea>
Formicidae> Myrmicinae> Trachymyrmex.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.645 |
Instability index | 63.59 |
Isoelectric point | 6.25 |
Molecular weight | 25554.37 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07017
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 110.90| 29| 32| 96| 124| 1
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70- 89 (20.55/ 8.72) ...........LKEAEQILATAIYQAKQKLQ
96- 124 (52.54/31.64) KRPVPSE.EL.IKYAHRISATNAICAPLTWQ
129- 157 (37.82/21.09) RRPYPTDlEMrVGFLGRLSDPSNL..PLNGQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 60.96| 15| 15| 172| 186| 2
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172- 186 (29.63/16.50) AGHPAGEPPVSQSNQ
188- 202 (31.33/17.79) AWHPSGEIHMSVGGQ
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