<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07016
Description |
Mediator of RNA polymerase II transcription subunit 15 |
Sequence | MATDDSWKTPHFRQSVVAKIDEAIQVSGMPTTKNSIEMENHVFQKAKSKEEYLGFVARLILHVREMNSKKGATGNAPGTAGTNNQGMPDPIGALQTLARQGTGNNQMMSMGGPNHQGIIPQPPANTATNLLQSLNQRPAQPMNMPGMQNKMPGMGMMPSQTGGPMNHMGPIQSMQNNPMLTQMNQMGQGNIPPQMNQMVPGQMGQLGAGQMQQNMQSQMQTQLPGQMNNQITGPIGNIQTSIPQQMNQIGPGQLGPGQMQQQLNHIQRKPSEMMNTGFPGPRNVTPNQFLRQSPSPSAPSPAGLPSSNQMVASPALVPSPSPQHAIMTGPTRSVNSVGMASSPSSSLNTPGGVGATPSPQQEDQAYRDKVRQLSKYIEPLRRMIAKMSSEGNVDKLSKMKKLLEILSNPSKRMPLDTLLKCEVVLEKLDFKRGDGSVGPPVTTLKEHQIFSPLLEAVSAHLQSPVINHTLQRTFGPCLDALFGPEIKNLPPPLKKQKIEESSSEIPDVLQGEIARLDQRFKVSLDPAQQSGSRCIQLICWLDDRHLPCVPPISVTVPADYPSTPPRCVMAPHEYEATTFLCAVQKALNVRIAKLPRRFSLSQLLDTWEMSVRQASAPKEMSITASTVLMGL |
Length | 631 |
Position | Tail |
Organism | Trachymyrmex zeteki |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea>
Formicidae> Myrmicinae> Trachymyrmex.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.485 |
Instability index | 58.87 |
Isoelectric point | 9.39 |
Molecular weight | 68564.27 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364148
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP07016
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
6| 364.06| 49| 50| 186| 234| 1
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74- 122 (58.03/18.70) .....GNAPGTAgtnNQGM......PDPIGALQTLARQGTG...NNQ....MMSM....GGPN...HQgiI....PQP
125- 164 (59.60/19.41) NT..ATNLLQSL...NQR.......PAQ.......PM..NM...PG.....MQNKMPgmGMMP...SQ..T....GGP
168- 185 (32.65/ 7.23) MG......PIQ...................S.....MQNN..............PML..TQMN..............Q
186- 234 (98.85/37.15) MG..QGNIPPQM...NQMV......PGQMGQLGAGQMQQNM...QSQ....MQTQLP..GQMN...NQ..I....TGP
235- 296 (58.82/19.06) IGniQTSIPQQM...NQIG......P...GQLGPGQMQQQLnhiQRKpsemMNTGFP..GPRNvtpNQ..FlrqsPSP
302- 350 (56.11/17.83) AG..L....PSS...NQMVaspalvPSPSPQ..HAIMTGPT...RSV....NSVGMA..SSPS...SS..L....NTP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.91| 17| 22| 440| 456| 2
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440- 456 (29.57/19.59) PVTTLKEHQIFSPLLEA
464- 480 (32.34/22.10) PVINHTLQRTFGPCLDA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 35.36| 10| 30| 526| 535| 4
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526- 535 (19.62/ 9.13) PAQQSGS..RCI
557- 568 (15.74/ 6.03) PADYPSTppRCV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 64.13| 20| 24| 579| 600| 5
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579- 600 (29.19/24.52) FLCAVQkaLNVRIAKLPRRFSL
603- 622 (34.93/22.70) LLDTWE..MSVRQASAPKEMSI
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