<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07006

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYVIPTLEYFSQGGIEDREYVAENSTTLYGIVVYHAADCLPSPCTETLGPYSNPHKLLMVLDKLEMVGGKGESFANIGEGLATGLQCFEDLQLRREPNTASQKHCILICNSPPYQTMIQETYKFAGHTIEQLATIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTAATTAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQPPSSLLNVAAFNQRLDVAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQRATMSMAAQPTHSQPGSQLTASCISQSVPTQVSQTVTASQQAPVSVSSITQQITHSQAQGNVSTGAVQNQQLVPRERQNIWQGIVEWIEKAKNPTDAQKQTRHVPCQVSANAKDGDPELKADTWPPKLIMQLMPKQLIGSIGGTYLKNSKSVVFHPTPCEALESLTKMMTAGFAGCVHFTSASSSPACEIKVLILLYTADKKTYLGFIPNDQTAFVDRLRKVIQQQKTSQNASVRQANPGPGNTIPTPMPTTGTQGGILMSQTNTMAMGGGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGISGPQANTGGGGMIGQQRPPYDDIEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQQPQPQYSVRQVFGVQQQMVGPRGQIATRPMAPGNAQNQQFEDVSNYDFLG
Length879
PositionUnknown
OrganismTrachymyrmex zeteki
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.05
Grand average of hydropathy-0.523
Instability index52.64
Isoelectric point8.88
Molecular weight96045.39
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07006
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.98|      27|      30|     256|     282|       1
---------------------------------------------------------------------------
  256-  280 (40.57/14.10)	..NTNQVQQNIAP....PNQQ...QGPPFRNQ..AP
  281-  313 (30.91/ 8.78)	PQNITSVHQTVTPsmaaPMNT...ARPPYNPQiaAP
  649-  672 (26.50/ 6.36)	PGNT......IPT....PMPTtgtQGGILMSQ..TN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     226.20|      41|      42|     733|     773|       2
---------------------------------------------------------------------------
  360-  394 (29.55/ 9.23)	..........LLNVAAFNQRLD.VAgnnvmaanQQQQQQQLTQQ....QQ
  397-  429 (39.54/14.76)	RLTMQLQQQNV....Q.RATMSmAA........QPTHSQPGSQLTA....
  733-  773 (69.71/31.42)	DDIEIARHQNLLKIQHLRQTLE.AA........QQQEAQYKSQLEVNIQQ
  774-  793 (30.99/10.03)	.........N..........LE.VA........QQQEMQYKQQLEA..QQ
  812-  845 (56.41/24.07)	RLMRPVSTNNL....GLRHLL............QQPQPQYSVRQVFGVQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.74|      18|      29|     523|     551|       3
---------------------------------------------------------------------------
   87-  104 (32.38/10.77)	PHKLLMVLDKLEMVGGKG
  533-  550 (33.35/13.38)	PPKLIMQLMPKQLIGSIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.79|      13|      28|     181|     193|       4
---------------------------------------------------------------------------
  181-  193 (23.95/14.20)	PRKIPAL..YKLFEK
  210-  224 (18.83/ 9.87)	PRHLVLLrnYNLKER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.94|      25|      28|     457|     482|       5
---------------------------------------------------------------------------
  457-  481 (41.16/21.10)	ITQQITHSQAQGNVSTGAVQNQQLV
  488-  512 (41.78/22.69)	IWQGIVEWIEKAKNPTDAQKQTRHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.24|      13|      27|     566|     579|       6
---------------------------------------------------------------------------
  566-  579 (20.15/19.79)	P.CEaLESLTKMMTA
  594-  607 (19.09/12.58)	PaCE.IKVLILLYTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.86|      13|     523|     318|     337|       8
---------------------------------------------------------------------------
  318-  337 (18.02/27.34)	PPGvNIATRPrwmrpfIAPG
  850-  862 (28.84/14.92)	PRG.QIATRP......MAPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.77|      14|      42|     677|     691|       9
---------------------------------------------------------------------------
  677-  691 (24.22/19.40)	GGGQITQ.NV....VStAPP
  698-  715 (16.15/ 6.02)	SGPQMTQmNMqnsgIS..GP
  721-  731 (23.40/12.86)	GGGMIGQ.Q........RPP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07006 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKNPTDAQKQTRHVPCQVSANAKDGDPELKA
2) GGGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGISGPQANTGGGGMIGQQRPPYDDIEIARHQ
3) QQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQ
4) QQKTSQNASVRQANPGPGNTIPTPMPTTGTQGGILMSQTNT
5) RPVSPQMGGNVHNTAATTAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLT
6) VAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQRATMSMAAQPTHSQPGSQLTASCI
7) VSVSSITQQITHSQAQGNVSTGAVQNQQLV
499
677
780
633
224
372
452
529
741
829
673
354
432
481










Molecular Recognition Features






MoRF SequenceStartStop




NANANA