<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07002

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRDTPMQRICSELTEKLLKSLDKEYNVVDIRAVVDVISTLEKTTVTKEVLEITRLGKHINELRRKTSNEALAKRAKDLVRRWRDMVLPTVHSMSSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLPLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTINHRISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYPSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSSQKNSQSLHRGLPSSDTSTGKTQKAARLRAAENCRESPSPESCQDRLREDDRISGTTAETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERLHIQCIEGLNGNFQPRLSMATACSDGDERSNARDGGNRVSGLSNVDSVKSVHNNQTDNVEFREWHQMLARPSYQGEILNIMPYVIID
Length568
PositionUnknown
OrganismTrachymyrmex zeteki
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.02
Grand average of hydropathy-0.846
Instability index62.56
Isoelectric point8.49
Molecular weight63004.72
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP07002
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     143.52|      37|      41|     140|     180|       1
---------------------------------------------------------------------------
  143-  179 (60.95/32.55)	LSVHSDHSRSPNASSNNKQSITLTINHRISSCSRNAS
  245-  265 (26.52/ 8.24)	................NSQVPSPTLKERISDCFAETS
  394-  427 (56.05/23.23)	LRAAENCRESPSPESCQDR...LREDDRISGTTAETS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.85|      12|      27|     323|     339|       2
---------------------------------------------------------------------------
  323-  338 (20.53/20.65)	RGSNCSPIGsanaLPS
  369-  380 (21.32/ 6.54)	KNSQSLHRG....LPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.74|      17|      21|     447|     467|       5
---------------------------------------------------------------------------
  447-  467 (27.61/24.39)	PPLDPSSidwgEDEERDDAEC
  470-  486 (32.13/16.73)	PPRDATA....EDLERLHIQC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.04|      26|      26|      93|     118|       7
---------------------------------------------------------------------------
   67-   89 (32.42/19.52)	..SNEALA.KRAKDLVRRWRDMVLPT
   93-  118 (44.21/29.36)	MSSQPTLALNGAKEMALRNLKPQSPA
  122-  142 (36.41/22.85)	LKPHSPLPLKDA..TPLRVL...SPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.57|      19|      21|      24|      44|       9
---------------------------------------------------------------------------
   24-   44 (23.96/26.73)	EynVVDIRAVVDVISTLEKTT
   48-   66 (30.61/23.99)	E..VLEITRLGKHINELRRKT
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP07002 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) CSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYPSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSSQKNSQSLHRGLPSSDTSTGKTQKAARLRAAENCRESPSPESCQDRLREDDRISGTTAETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDA
2) MSSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLPLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTINHR
3) RLSMATACSDGDERSNARDGGNRVSGLSNVDSVKSVHNNQT
174
93
497
474
170
537

Molecular Recognition Features

MoRF SequenceStartStop
NANANA