<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP07000

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSSETQITSILNDILKVEAIEEAFSCVLVHHPKKETDKVAAWHQELRTAMTGLTKEQQEAAVRQFLSMAAAMTNHRRLQLLLSLLENLVHSNFLPARLVCECILSCDKLQYQLEDFWIECFVLIKHILGGVDYKGVREIMKGCKEKAQTIPARLDASVQPQLKALENVIEFIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSDFVESFRHTAQMVSIVGHSKMLPVVEHTGYADYLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCVVLEEQLVELVILAMERSENETLPAEGMDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPGTNIHRPIPHTLKVHHEFLQHLVMPNASLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQPLQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGADSLSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPGTPPLFLCLLWKMILETDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDRLVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRRLVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPELDYYIRLVQRIVETMSGTAHFPATDWRFNEFPNPAAHALYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLINWQYNNLTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERPHCVVELAVCLYEMLERVDHTQTTLNYMDSICDLLYHIKYMFVGDMTKNEVECIIRRLRPALQMRLRFIAHINIDEIHTS
Length1357
PositionTail
OrganismTrachymyrmex zeteki
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.09
Grand average of hydropathy-0.034
Instability index46.88
Isoelectric point6.73
Molecular weight155563.98
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP07000
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.73|      34|     148|     454|     495|       1
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  454-  495 (56.85/46.00)	IHRPIPHTLKVH...........HEFLQHLVMPNaslcmgsdYRIALLCNAYS
  603-  647 (54.88/29.30)	ISQLLPTVFKSHawgtlytllemFSYRMHHIQPH........YRVQLLSHLHS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     499.71|     174|     260|     799|    1016|       2
---------------------------------------------------------------------------
  799- 1016 (261.31/255.75)	PGTPplfLCLLWKMIL...ETDRIS..P.IAY..KILERIgARALS..AHLrKFCDYLVFEFANSVGGQHVNKCVDTINDMIWK..............YNIVTIDRLVL...ClalrtqegneaqvcffiIQLLLLKAAE.....FRNRVQEFVkeNSPehwKQSNWHEKHLAFHRKFPEKFAPEGIME.QTS............GGPSQyqnlpvyfgnvcLRFLPVFdivVHRYLEipPVIKSLEILLE..HL.G.CLYKFH.DRP
 1055- 1278 (238.40/147.80)	PGWA...LSEAYQMYMtrfNDDAVSwvPeLDYyiRLVQRI.VETMSgtAHF.PATDWRFNEFPNPAAHALYVTCVELMALPVAPdavanflldvvakgYTVVPSDEIHLwinC.................VGLLLAALPEcywsaLHKRLLETI..SSP...GLINWQYNNLTPFQMFNFNITHNSLLEnKYSymlalahsvwhhAGVGQ............ITTMPQF...IKEKLQ..PVVSSEEQLIYacHLiGpTLARFNaERP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.57|      24|     557|     180|     215|       5
---------------------------------------------------------------------------
  184-  208 (41.88/46.65)	FIVNEIQKAyPDGKNWPHWKLAKLL
  389-  412 (42.69/15.44)	FISGSIQRN.PLSNFLPVLKLYDLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.54|      52|     260|      53|     109|       6
---------------------------------------------------------------------------
   55-  107 (86.27/53.47)	KEQQEAAVrQFLSMAAAMTNHRRLQLLLSLLENL.VHSNF.LPARLVCECI.LSCD
  517-  571 (77.27/40.61)	KNQQQQPL.QNLQNNAALANGPTTPLSMSILDSLtVHSKMsLIHSIVTHVIkLAQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.52|      45|     582|     126|     176|       7
---------------------------------------------------------------------------
  126-  176 (71.28/62.83)	HILG.GVDYkgvreiMKG..CKEKAQTIPARLDAS.VQPQLKALENVIEFIFDRN
  714-  762 (66.24/45.19)	HVTGtGADS......LSGtwCKELLNTIMQNTPHSwANHTLQCFPPVLSEFFQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.05|      19|     137|     219|     249|      13
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  229-  249 (30.25/46.62)	KMLPVVEHT....GYADYLINpwLL
 1290- 1312 (30.81/12.51)	EMLERVDHTqttlNYMDSICD..LL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP07000 with Med23 domain of Kingdom Metazoa
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