<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06921

Description Cyclin-dependent kinase E-1
SequenceMGDGSGSRGNRAEWVQQYDLLGKIGEGTYGLVFLARTKSPSPSKSIAIKKFKQSKDGDGVSPTAIREIMLLREIAHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKLNHSINQYTVKSLLWQLLNGLSYLHSNWMIHRDLKPSNILVMGEGEEHGVVKIADFGLARIYQAPLKPLSENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEVKATSNPFQLDQLDKIFKVLGHPTIEKWPSLTSLPHWQQDVQHIQGHKYDNTGLYNVVHLSPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFKIEPLPGRNALVPCQLGEKIVNYPTRPVDTTTDLEGTTNMPPSQTVTAVSGMPGAHGSNRSVPRPMNVVGMQRMPPQAMAAYNLTSQAAMGDGMNPGGISKQRGVPQAHQPQQLRRKDQMGMPGYPAQQKSRRL
Length461
PositionKinase
OrganismCajanus cajan (Pigeon pea) (Cajanus indicus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Cajanus.
Aromaticity0.07
Grand average of hydropathy-0.402
Instability index40.56
Isoelectric point9.16
Molecular weight51499.52
Publications
PubMed=22057054

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06921
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.87|      26|      31|     393|     423|       1
---------------------------------------------------------------------------
  363-  380 (28.69/10.84)	GT..TNMPP.........SQTVTAvSGM.P
  397-  423 (47.65/40.98)	GM..QRMPPQAMAAYNLTSQAAMG.DGMnP
  425-  450 (41.54/21.01)	GIskQRGVPQAHQPQQLRRKDQM...GM.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.51|      23|      42|     299|     323|       2
---------------------------------------------------------------------------
  299-  323 (29.63/26.76)	PAyDLLSKMLEYdPRKRITAAQALE
  340-  362 (41.88/25.87)	PC.QLGEKIVNY.PTRPVDTTTDLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.23|      28|      42|     155|     184|       3
---------------------------------------------------------------------------
  155-  184 (44.60/34.19)	LVMGEGEEHGVVKIADFGLarIYQA..PLKPL
  200-  229 (45.63/28.68)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06921 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NYPTRPVDTTTDLEGTTNMPPSQTVTAVSGMPGAHGSNRSVPRPMNVVGMQRMPPQAMAAYNLTSQAAMGDGMNPGGISKQRGVPQAHQPQQLRRKDQMGMPGYPAQQKSRRL
349
461










Molecular Recognition Features






MoRF SequenceStartStop




1) GMPGYPAQQKSRRL
2) PSKSIAIKKFKQ
448
42
461
53