<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06909

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMFTNQPPGPPPPPPPPGPPGGPGPAGLLPAAAGPRNPNSTLVDELEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKEALIQKHLGKLRHWQQVLEDISVQHKKPAEMPQGPLAYLEQASANIPAPMKQT
Length175
PositionHead
OrganismAlligator mississippiensis (American alligator)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Crocodylia> Alligatoridae> Alligatorinae> Alligator.
Aromaticity0.05
Grand average of hydropathy-0.595
Instability index60.53
Isoelectric point5.42
Molecular weight19260.70
Publications
PubMed=22293439

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP06909
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.06|      15|      16|     102|     116|       1
---------------------------------------------------------------------------
  102-  116 (24.51/14.98)	QKPEQVIKEDVSELR
  120-  134 (24.55/15.01)	QRKEALIQKHLGKLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.14|      14|      18|     140|     155|       2
---------------------------------------------------------------------------
  140-  155 (21.65/17.81)	LEDISvqHKKPAEMPQ
  161-  174 (25.49/14.34)	LEQAS..ANIPAPMKQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP06909 with Med28 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MFTNQPPGPPPPPPPPGPPGGPGPAGLLPAAAGPRNPNSTL
1
41

Molecular Recognition Features

MoRF SequenceStartStop
NANANA