<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06904

Description Mediator of RNA polymerase II transcription subunit 24 isoform A
SequenceMVAKVRLGFGTKQGPQEVFSLCCAAGGLADLKDEGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAFYTEKFKEMLDQAAAENQLKMCLERLEKILDSMKNRALIHIAKLEETSSWSTVEQSLVKLGENLNNLSSPQLQSQADECISLIKSIPTMLSAHSDQLNKTGFPTIHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTSLLLQECSKQGLLSETNMTNLTAKRTADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHISGEGSKAASVRALLFDISFLMLCHVAQTYGSEVILSESSPTGEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTGVFTKVLEKGWVDSSSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYSVFCLDMQQLTLTLLGHILPNLLTDSSKWHMLMDPPGKALAKLSVWCALSSYSSHNRGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length987
PositionTail
OrganismAlligator mississippiensis (American alligator)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Crocodylia> Alligatoridae> Alligatorinae> Alligator.
Aromaticity0.06
Grand average of hydropathy0.014
Instability index46.24
Isoelectric point6.17
Molecular weight109870.79
Publications
PubMed=22293439

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06904
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     217.57|      59|      69|     181|     239|       1
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  181-  239 (97.53/70.09)	LEETSSWSTVEQSLV...KLGENLNNLSSPQLQSQA.DEC.ISLIKSIPTMLSAHSDQLNKTGF
  248-  306 (75.90/52.68)	LEGTMNLTGETQPLVeqlMMVKRMQRIPSPLFVLEIwKACfVGLIES.....PEGTEELKWTAF
  391-  427 (44.13/27.12)	............PRL...KSAENANIQPNPGLILRA.EPT.VTNI..LKTMDADHS........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.27|      44|     193|     322|     370|       2
---------------------------------------------------------------------------
  322-  370 (77.07/56.45)	PQGEKDFTED..VNCAFEFLLKLTPlldkaDQRC.NCDCTSL.....LLQECSKQGL
  516-  567 (68.20/40.37)	PTGEVPFFETwmQTCMPEEGKILNP.....DHPCfRPDSTKVeslvaLLNNSSEMKL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06904 with Med24 domain of Kingdom Metazoa
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