<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06893

Description Uncharacterized protein
SequenceMAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINNWFTDLAGTKPLTHLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAITETKVKKRHVIDPFIEWTQIITKYLSEQLQKIAEFYRQLPGQGCGSPSGPMPQEVEQALKQWDYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRSGEDEFLKMLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLAMQLDGAGGHPPHILSTQTGNALPSTPTPQPATGNPPPSPFSDLLLCPQHRPVVYGLSCILQSIILCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPGGTSAFTQQVRAKLREIEQQIKERGQAVEVRWSFDKCQETTAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLYNRIFGLGPSKDSHEISPDDDAVVALLCEWAVSYKRSGRHRAMVVAKLLEKRQAEIEAERCGDSEVVDEKGSISSGSLSAASAPVFQDVLMQFLDTQAPMLTDPGNENEKVEFFNLVLLFCELIRHDVFSHNIYMCTLISRGDLAMDSHGPRPPSPFDDPAEDHDRKEAEGSSGIKLEDTGLSESMDIDHNSSVLFDDMEKTDFSMFSPPMHCESKASPSPEKPDPEKEAKPLLKEKCAEGTLASLYDQPRHIQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKSTAETSGEEGQKRKRSKPEAFPTAEDIFAKFQHLSHFDQHQVTSQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLNISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHSCLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSDSNMLWEPEFMIETIENPSAQNFTYTNLGKSLNENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQQDGNKSTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFSHPGGVDDLMDDELGAKKPGGRAVSIETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSIQAQRLMQLICYPHRLLDSEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSGSSTGNAAGSLGSSASTAPASTKSKAILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRKVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVTLEPEKKAVEPVKADKASSNPAASTEERKKKQKSKKRNQSANKSEDFMLGPGRVPYGVGMPTDLLHHQAGSSMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRTSYSAVLPSAMGSMMGIDPSYKPTAYRQQPPVPQGQLLRQQLQAKLQGQGILGQPQVRPMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPAYSNPPYQNSHPGSTPALVDPIRQMQQRPSGYVHQQAPGYGHALSSAQRFPHQSLQQAPMMGGMNHMSTQGVPTGIRPSQMLPDQQQQQQQYLRQQQQQMLRVSGAHCTILPFLITGKPDVRQGKG
Length2083
PositionKinase
OrganismAlligator mississippiensis (American alligator)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Crocodylia> Alligatoridae> Alligatorinae> Alligator.
Aromaticity0.07
Grand average of hydropathy-0.400
Instability index51.94
Isoelectric point6.67
Molecular weight231689.38
Publications
PubMed=22293439

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06893
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.23|      16|      18|    1643|    1660|       1
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 1643- 1660 (19.84/21.78)	GSLIDTKgNKIAGFDsIF
 1664- 1679 (30.39/19.85)	GLQVSTK.QKISPWD.LF
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     333.67|      82|     108|    1882|    1963|       2
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  342-  404 (75.24/40.30)	.........PSP.....FSDLL........................LCPQHRPVV....YGlscILQSIILCCPsaLVWHYSLTDSRIKTGSpldHLP..IAPSNLP
 1882- 1963 (158.12/94.62)	KPTAYRQQPPVP.....QGQLLRQQLQAKLQGQ.G.........ILGQPQVRPMAPTPSYG...ALQPSQGYTP..YVSHIGLQQHPSQSGT...MVP..PAYSNPP
 1968- 2025 (70.56/37.23)	.............................HPGStP.........ALVDP.IRQMQQRPSGY...VHQQAPGYGH..ALS..SAQRFPHQSLQ...QAPmmGGMNHMS
 2029- 2079 (29.75/10.49)	VPTGIRPSQMLPdqqqqQQQYLRQQQQQMLRVS.GahctilpflITGKPDVR.......................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.25|      72|     108|     922|     995|       3
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  922-  995 (119.19/89.02)	LNQDQmAQVFEGLCGVVKH.GMNRSDGSSAERcILAYLYDLYTSCSHLKSK.FGELFSDFCSKVK.....NTIYCNVEPSD
 1026- 1104 (115.06/75.64)	LNENP.ANRYSFVCNALMHvCVGHHDPDRVND.IAILCAELTGYCKSLSAEwLGVLKALCCSSNNgtcgfNDLLCNVDVSD
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.45|      54|     111|     536|     591|       4
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  536-  591 (86.03/63.14)	EAErcGDSEV.VDEKGSISSGSLSAASAPVFQDV.LMQFLDTQAPMLTD....PGNENEKVE
  647-  706 (84.42/54.58)	EAE..GSSGIkLEDTGLSESMDIDHNSSVLFDDMeKTDFSMFSPPMHCEskasPSPEKPDPE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.63|      11|     111|     213|     223|       5
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  213-  223 (25.18/10.58)	GCGSPSGPMPQ
  324-  334 (22.45/ 8.69)	GNALPSTPTPQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     477.37|     160|     223|    1124|    1300|       7
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 1124- 1300 (245.91/184.98)	LLLEDLIRCAA...IPSLL.NAACS.....EQDSEPGA.RLTCRILLHLFKTPQLNPCqqdGNKSTvGIRSSCDRH...LLAASQNRIVDGAVFAVLKAVfvlGDAELKGsgfSHPGGVDDLMDDELGAKkpggravSIETASLDVYAKYVLRSICQQEWVGERCLKSLCED.....SNDLQDPVLSSIQAQRLM
 1340- 1517 (231.47/138.33)	LELQLMIKQTAnneMNSLLeNIAKAtievfQQSAETSSgSSTGNAAGSLGSSASTAPA...STKSK.AILSSLERSgvwLVAPLIAKLPTSVQGHVLKAA...GEELEKG...QHLGSSSRKERDRQKQK.......SMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQvqqivTNWREDQYQDDCKAKQLM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.85|      30|     104|    1722|    1753|       8
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 1722- 1752 (52.07/31.64)	PRSYYLEPLPLP...PEEEEPPTPVTLePEKKAV
 1825- 1857 (49.78/25.39)	PVGLYAQNQPLPaggPRLDTSYRPVRM.PLGKLV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06893 with Med12 domain of Kingdom Metazoa
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