<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06855

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYVIPTLEYFSLGGIEEREYVAENSTTLYGIVVYHAADCLPSPCTETLGPYSNPHKLLMVLDKLEMVGGKGESFANIGEGLATGLLCFEDLQLRREPNTASQKHCILICNSPPYQTVIQETYKFAGHTIEQLATIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPSYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQPPSSLGLNVAAFNQRLDVAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQQATMSMAAQPTHSQPGSQLTASCISQSVPTQVSQTVTASQQAPVSVSSITQQITHSQAQGNVSTGTVQNQQLVPRERQNIWQGIVEWIEKAKNPTDAQKQTRHVPCQVSANAKDGDPELKADTWPPKLIMQLMPKQLIGSIGGTYLKNSKSVVFHPTPCEALESLTKMMTAGFAGCVHFTSASSSPACEIKVLILLYTTDKKTYLGFIPNDQTAFVDRLRKVIQQQKTSQNASVRQANPGPGNTIPPPMPTTGTQGGILMSQTNTMAMGGGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGINGPQANTGAGGMIGQQRPPYDDIEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQQPQPQYSVRQVFGVQQQMVGPRGQIATRPMAPGNAQNQQFEDVSNYDFLG
Length880
PositionUnknown
OrganismTrachymyrmex septentrionalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.05
Grand average of hydropathy-0.506
Instability index52.53
Isoelectric point8.80
Molecular weight96083.46
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06855
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     263.02|      39|      42|     400|     438|       1
---------------------------------------------------------------------------
  226-  266 (34.76/ 8.75)	VSPQM.............GGNVhnTAATAAQ.I.P..lspL......Q......SN......D...SPNTNQVQQNIA.....P
  298-  327 (33.60/ 8.23)	....P.............MN....TA......R.P.....S......Y......NP......QiaaPPNYHPPGVNIAT...RP
  328-  383 (28.95/ 6.15)	RWMRPfiapgatapantqGSAL..IAQ.LTQP..P....sS......L......GLnvaafnQ...RLDVAGNNV.MAA...NQ
  384-  419 (46.46/14.00)	QQQQ...............QQL..T....QQQ.........qqlrltM......QL......Q...QQNVQQATMSMAA...QP
  420-  462 (37.83/10.13)	THSQP.............GSQL..TASCISQSV.PtqvsqT......V......TA......S.......QQAPVSVSSitqQI
  782-  822 (43.56/12.70)	QEMQY.............KQQL..EAQQAQRGLnP....aA......M......AN......Q...QANSQRLMRPVST...NN
  823-  859 (37.86/10.14)	LGLR................HL......LQQPQ.P.....Q......YsvrqvfGV......Q...QQMVGPRG.QIAT...RP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.79|      13|      28|     181|     193|       2
---------------------------------------------------------------------------
  181-  193 (23.95/17.54)	PRKIPAL..YKLFEK
  210-  224 (18.83/12.16)	PRHLVLLrnYNLKER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.06|      20|      21|     739|     759|       4
---------------------------------------------------------------------------
  739-  759 (29.54/19.57)	ARHQNLLKIqHLRQTLEAAQQ
  762-  781 (33.52/17.91)	AQYKSQLEV.NIQQNLEVAQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.74|      18|      30|     524|     552|       5
---------------------------------------------------------------------------
   87-  104 (32.38/12.98)	PHKLLMVLDKLEMVGGKG
  534-  551 (33.35/16.14)	PPKLIMQLMPKQLIGSIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.99|      21|      43|     666|     692|       6
---------------------------------------------------------------------------
  666-  692 (32.67/28.84)	GILMSQTNTMAmgGGQITQNvvstAPP
  712-  732 (42.32/21.79)	GINGPQANTGA..GGMIGQQ....RPP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06855 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKNPTDAQKQTRHVPCQVSANAKDGDPELKA
2) GGGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGINGPQANTGAGGMIGQQRPPYDDIEIARHQ
3) QQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQ
4) QQKTSQNASVRQANPGPGNTIPPPMPTTGTQGGILMSQTNTM
5) RPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPSYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQ
6) VAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQ
7) VSVSSITQQITHSQAQGNVSTGTVQNQQLV
500
678
781
634
224
373
453
530
742
830
675
355
405
482










Molecular Recognition Features






MoRF SequenceStartStop




NANANA