<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06853

Description XK-related protein
SequenceMHNINRERSNVTWIALALQAVWRSSMLISRFIVLVLALIFLKVWFFLFLGLHWFIMTIWVILQKTKFCSTAWEERIYNCVIGLIYCFDFFNLRDDRSRYRVLIFYSVIAAQNVIFLIIYMLHAGETIAMIMIASVIVSCMLIGLTSMSLYYGKFHPSRTATNISRNISEHSTTTKVEASRSFKLFHRDSLVSLHHSMDISPRTEEVPTDKQSLLTNIAQISDCVEEGIVNRNYSSENEFNASALRLSTECERPHSRVGVKHKEEATSVNDNNPDNALTSSAPLNSLYSGLPDIDSSRKRRGIYEHDITPQLDWHAPDILNIDLDQLGNLDNSERSNSLTLDSCSKVIGALDVIKNREKLTTPTPLESNRIFDIEKQRDETMSCVTSIHDYENVCPLGIARPPWCIRSWKGYTDIETYIHDDSVVRDRRRDTLTSTTGTTYSSEYSDGMISRGILKQDDYADALTYDLVESKGNKSSYSDSTFSTSTDDQNASLYIAKPVVFDDRGGMLALDTILEERDDLSSSDEKFQHGSELSRDSASTLVSTIDQIRRYTAENSPRHIYHTTGTHWEDLNPKNLMAQAHFAKVLFDNDLRNASTTTGSIDLTARDVEKREIDAIREFVRCCAIESIKKTPLIDAVLSDSPILDKASKLMRQVTFADCKNDFDTNESDLYVEMSPLVSVENGENLCQARSIDAKTGEAESDTLKRNTLPTISEKSPNKENLSPSLSNNNRRINNIYDDRDNNDSHAWTIERDEKNDKSLCNMRFNLKEKRHLFLEQVLSPVPKLWNKPGQPSPGGGSASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGSPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSRGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGVLAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDTLNSDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLIASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISTLKCRLYGMSMTTNVEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGANSTSTSMLNPLQLGALLGQAKNSVTSNSNTNERGKKTRKRKTGTDGLWRSPKRKSDGGDSSAATEILLESSSSENSTPLGTPTSRENLASETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSAEQQQQQQQQPQQEVEELIKIRESSSTRKSKKNRSGGGSEEKKSSPTNIFVDETSTTNSGNKSLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTPSPKTSGLTSATEDRQRSERKSGGGKSSGSSSKSSSEDTKSGGSKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGSAGVGLSCSSSRPTSPAAVKKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCSKSVQSPKHSPVYGSTVSVPVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSNKDSSGRGDKDRRTSSISSSGGSGSGHQSPKTKSSSGKMKQLEMISPGSETTQVSLQASGGSTPPSGQIDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDACGNGGGNVKGSGSSGLGSTGGMSSAGQKEKNIGSGGGSSSSGGKAIGEGGKSCVTKNASVDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSNVTTGSNGSPKTHTGLKPGVNSGPASKKPQTLQAAQKMLPTKMMLAASGMKSAISSSSTTNTGSSAGITASATGGVAGNPLSKSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISNLPPSLPPQLMMEGLMKQLDTKFQIPKLSARANVADADKNKSSDKLSILSDSKQTLDGLKQEQGKIAGLSNVTVSVSKSSQPDDQSRRDHSQTKPDNLSITTSAAGAMSLNLVGENTGLMLPSQSTADSDVPTNLCIQPMVDNEPSRDSCKDLGIRQTSTGQQFLGKIDDTSVGGILSKSNVSDQLTSSGAKSYGTLTSSNTSTTPSGAIVTESLNLSTKPADQAILQTKYNKITAEEKKQQQTSSASLSSSSSSSSSSSSSIFSSLASAATSSDAAAEMLLDFSAANKDTMTKGGHGLPASLTQHHLTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length2616
PositionMiddle
OrganismTrachymyrmex septentrionalis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.04
Grand average of hydropathy-0.507
Instability index55.19
Isoelectric point8.65
Molecular weight280959.81
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06853
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.98|      11|      15|    1573|    1584|       2
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 1573- 1584 (17.77/11.77)	P.GIEIIPIAsSP
 1590- 1601 (19.20/ 7.96)	PsSITITPIA.GP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|    1020.43|     220|     239|    1862|    2095|       8
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 1325- 1550 (215.33/67.83)	.NLGSGA....NSTSTSmlnplqlGALLGQ..AKNSVTSNS.....NTNE.......RGK......KTRKRKTGTD.GLWRSPKRKSDGGDSSAATeillESS.......................SSENSTPLGTPTSRENLASETrTS.....................TPTSATSLTSGMDFSNldttdildK............................................................................................................................SASDYDLDNSEKDSEIME....VQHSAEQQQQQQQ..........QPQQEVEElikiressstrKS.KKNRSGGGSEEKKSSpTNIFVD.E......TS...............TTNSGNKSLPV..PPSVSitpiscG.
 1622- 1737 (72.81/18.30)	............RKSGG.......GKSSGSS.SKS.....SSEDTKSGGSKLEKR...............RKRKRE.DGPMGPPDKVPSGGKQQQD....PLS.......................KPV.SVSIKPSTEQSPPSGGS.AGvglscsssrptspaavkkfspSPTHSSSLATLV..GK........S........................................................................................................................................................................................................................................................................
 1862- 1961 (110.42/31.37)	....................................................................................................................................................................................................sptlkagqsaaatcsksvqspkhspvygstvsvpvpvpasaspkhgntsspkhgssaassgkpsmsalksaanspssksssssssdsattpskvksssssssnkdssgrgdkdrrtssisssggSGSGHQSPKTKSSSGKMKQLEMISPGSETTQVSLQASGGST....PPSGQIDA...........AS.KSAIAAQQARNRKSS.LNAVIDKLKNAQHCTE...............TDACGNGGGNV..KGSGS......SG
 1976- 2159 (272.77/88.49)	KNIGSGG....GSSSSG.......GKAIGEG.GKSCVTKNASVDTKNPGEYMVKHSSDGI......KITINKTRTK.DSKQAANLKLSSSGSMAAT....SSS.......................SSLSSVASSSSSSSSNVTTGS.NG.....................SPKTHTGLKPGVNSG..............................................................................................................................................................PASKKPQ.TLQAAQKML....PTKMMLAA...........SGmKSAISSSSTTNTGSS...AGI..........T...............ASATGGVAGNPlsKSSSS......KA
 2160- 2409 (205.21/64.31)	....SGS....PKTSSG.......VTDLSRGrDKPRISKSG.....DKGIFASKGLGDAR......KSSPSALREEsESERAFKL.LAAHASISNL....PPSlppqlmmeglmkqldtkfqipklSARANVADADKNKSSDKLSIL.SD.....................SKQTLDGLKQ..EQGK.......iA................................................................................................................glsnvtvsvsksSQPDDQSRRDHSQT.KPDNLSI..TTSAAGAMSLNLVGENTglmlPSQSTADS...........DV.PTNLCIQ...........PMVDNEPSRDSCKDlgirqtstgqqflgkIDDTSVGGILS..KSNVS........
 2410- 2555 (143.89/41.61)	DQLTSSGaksyGTLTSS.......NTSTTPS.G.AIVTESLNLSTK.PAD.......QAIlqtkynKITAEE...K.KQQQTSSASLSSSSSSSSS....SSS.......................SIFSSLASAATSSDAAAEMLL.DF.....................SAA.........NKDT........M............................................................................................................................TKGGHGLPAS......LTQHHLTIPERAMTQAAPTVRRNTP....PP.............................................................................................
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     617.52|     198|     223|     579|     792|       9
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  461-  567 (63.38/26.68)	...............................................................................................................................................DALTYDLVESKGNKSSYSDStFSTSTDDQNASLyiakPVVFD.DRGGM.LALDTILE..ERDDLS.SSDEKFqhgselsrdsastlvsTIDQIRRYTAEN..SP.RHI.YHTTGTH
  579-  792 (303.13/211.88)	QAHFakvLFDNdLRNASTTTGSIDLTARDVEKREIDaiREFvrccAIESIKKTPL...IDA......VLSDSPILDKASKLMRQVTFADCKNDFDTNE....SDlyveMSPL.VSVENGENLCQARSI......DAKTGEAESDTLKRNTLPTISEKSPNKEN.LSPSLSNNNRRI....NNIYD.DRDNN.DSHAWTIERDEKNDKS.LCNMRF................NLKEKRHLFLEQvlSPVPKL.WNKPGQP
  807- 1013 (251.01/143.81)	QMEF...LMEK.LRSKSSTYKPLVETAKNMRMAMLD..KRF....AIDSIEKNQLqkcLDTlqhsikVTSFQSMVERLESLARQLGLKFMMSGSPGTEifisSD....MFFLeVLLEPPSGLVRDVKIhhegksEQQSCEALASALSRGDFVDFTTQ...LEG.LAS...............IYQlNADKKvKCKAFSALQSLEADLGvLAQLQT................FMKEPFNLVHK...SPVGILeRRRGGHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     265.63|      84|     105|    1093|    1183|      12
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 1093- 1183 (139.17/121.58)	LPACFVLKLVKKMPicmelVKRIQKVTELECGDISAPHplLSLIIQH.....ASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEG.VL.VC.SIPFT
 1200- 1291 (126.46/91.45)	LFNCLIASCVRPMA.....RQDPEHTTILEVSALSWQH..ISVSVEHpyeetMATAELDLTDISTLKCRLYGMSMTTNVEQTSDLSGrVLqRClSIPLT
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.37|      19|      24|    2556|    2574|      13
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 2556- 2574 (41.00/17.91)	PPPPPPLPAPFP.PAASPSV
 2582- 2601 (34.37/13.79)	PAPSPRVIPPSPhSSASPCI
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.15|      12|    1016|     793|     804|      16
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  793-  804 (23.50/ 9.95)	SP.GGGSASDKGK
 1787- 1799 (18.66/ 6.17)	SPkHGSSAASSGK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06853 with Med1 domain of Kingdom Metazoa
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