<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06847

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRDTPMQRICSELTEKLLKSLDKEYNVVDIRAVVDVISTLEKTTITKEVLEITRLGKHINELRRKTSNEALAKRAKDLVRRWRDMVLPTVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTSNHRISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSSQKNSQSLHRGGLPSSETSTSKTQKAARLRAAENCRESPSPESCQDRLREDDRISGTTETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERLHMQCIEGLNGNFQPRLSMATACSDGDERSNARDGGNGVSSGLSNVDSVKSVHNNQTDNVEFREWHQMLARPSYQGEILNIMPYVIID
Length568
PositionUnknown
OrganismTrachymyrmex cornetzi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.02
Grand average of hydropathy-0.874
Instability index62.44
Isoelectric point8.35
Molecular weight62916.44
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06847
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     516.37|     125|     138|     259|     384|       1
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   65-  170 (48.63/19.77)	.......................................................KTSN.EALAkrakDLVRRWRDMVLPTVHS.TPSQpTLALNGAKEMALR..NLKPQSPALRElkphsplslkdatplrvlspalsvhsdhsrspnASSNNKQSI...TLT.SNHR.
  174-  258 (87.61/39.55)	CSRNASpvLGTSNQNHVTEAVPRTHSSNKRLRK...EE.SSKDQ.CQYYQSPHgTESTI.EEVK....KQRLNGENIS.GNLNSqVPSP.TLKERIS.........................................................................
  260-  384 (202.03/104.28)	CFAETS..LETTNDESGPKKRGRKKGSKSAKRQSFLED.SVKEKLASISRNPK.LKTTQ.ELLA....DLQARGSNCSPGSANA.LPSQ.SVAEPPSTEDVLRGSNNEQVSKHLRC.................................SSQKNSQSLHRGGLP.SSETS
  400-  524 (178.11/94.32)	CRESPS..PESCQDRLREDDRISGTTETSTCRSPLQRDlTVEEILAKL...PP.LDPSSiDWGE....DEERDDAECFPPPRDA.TAED.LERLHMQCIEGLNGNFQPRLSMATAC.................................SDGDERSNARDGGNGvSSGLS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06847 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RLSMATACSDGDERSNARDGGNGVSSGLSNVDSVKSVHNNQT
2) TVHSTPSQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSITLTSNHRISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLETTNDESGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSSQKNSQSLHRGGLPSSETSTSKTQKAARLRAAENCRESPSPESCQDRLREDDRISGTTETSTCRSPLQRDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERL
496
89
537
481










Molecular Recognition Features






MoRF SequenceStartStop




NANANA