<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06846

Description XK-related protein
SequenceMHNINRERSDVTWVALVLQAVWRSGMLISRFMVLVLALIFLKAWFFLFLGLHWFIMTIWVILQKTKFCSTAWEERIYNCVIGLIYCFDFFNLRDDRSRYRVLIFYSVIAAQNVVFLIIYMLHVGETIAMIMIASVIVSCMLIGLTSMSLYYGKFHPSRTATNISRNISEHSTTTKVDASRSFKLFHRDSLVSLHHSMDISPRTEEVPTDKQSLLTNIAQISDCVEEGIVNRNYSSENEFNASALRLSTECERPHSRVGVKHKEEVTSVNDNPDNTLTSSAPLNSLYSGLPDIDSSRKRRGIYEHDITPQLDWHAPDILNIDLDQLGSIDNSEGSNSLTLDSCSKVIGALDVIKNREKLTTPTPLESSRIFDIEKQRDETMSCVTSIHDYENVCPLGIARPPWCIRSWKGYTDIETYIHDDSVVRDRRRDTLTSTTGTTYSSEYSDGMISRGILKQDDYADALTYDLVESKGNKSSYSDSTFSTSADDQNASLYIAKPVVFDDRGGMLALDTILEERDDLSSSDEKFQHESELSRDSASTLVSTIDQIRRYTAENSPRHIYHTTGTHWEDLNPKNLMAQARFAKVLFDNDLRNASTTTGSIDLTARDVEKREIDAIREFVRCCAIESIKKTPLIDAVLSDSPILDKASKLMRQVTFADCKNDFDTNESDLYVEMSPLVSVENGESLCQARPIDAKTTEAESDTLKRNTLPIISEKSPNKENLSPSLSNNNRRINNIYDDGDNNDSHAWTIERDEKNDKSLCNMRFNLKEKRHLFLEQVLSPVPKLWNKLGQPSPGGGSASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGPPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSRGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGVLAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDTLNPDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLIASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISTLKCRLYGMSMTTNVEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGANSTSASMLNPLQLGALLGQAKNSLTSNSNTNERGKKTRKRKIGTDGLWRSPKRKSDGGDSSAATEILLESSSSENSTPLGTPTSRENLASETRTSTPTSATSLTSGMDFSNLDTTDILDKSASDYDLDNSEKDSEIMEVQHSNAEQQQQQQQQQPQQEVEELIKIRESSSTRKSKKNRSGGGSEEKKSSPTNIFVDETSSSGNKGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTSSPKTSGLTSATEDRQRSERKSGGKSSGSSSKSSSEDTKSGGSKLEKRRKRKREDGPMGPPDKVPSGGKQQQDPLSKPVSVSIKPSTEQSPPSGGNAGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATGKPVQSPKHSPVYGSTVSVPVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKSSSSSSSDSATTPSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGSGHQSPKTKSSSGKMKQLEMISPGSEATQVSSLQASGGSTPPSGPVDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDACGNGGGNMKGSGSSGLGSTGGMSSAGQKEKNIGGGGSSSSSGGKTIGEGGKSCVTKNASVDTKNPGEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSSSSSNVITGSNGSPKTHTGLKPGVNSGPASKKPQTLQAAQKMLPTKMMLAAAGMKSAISSSGATNTGGGGGITASATGGVGGNPLSKSSSSSKASGSPKTSSGVTDLSRGRDKPRISKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISNLPPSLPPQLMMEGLMKQLDTKFQIPKLSARANIADADKNKSSDKLSILPDSTKQTLDGLKQEQGKIAGLSNVTVSVSKSSQPDDQSRRDHSQNKPDNLSITTSAAGAMSLNLVGENTGLMLPPQSTADSDVPTNLCIQPMVDNEPSRDSCKDLGMRQTSTGQQFLGKIDDTSVGGILSKSNVSDQLTSSGAKSYGTMTSSSTSTASSGAIVAESLNLSTKSADQAVLQTKYNKITVEEKKQQQTSSASLLSSSSSSSSSSASIFSSLASVATSSDGNPVMTSDSGGGGGGGGGHGLPASLTQHHLTTIPERAMTQAAPTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length2614
PositionMiddle
OrganismTrachymyrmex cornetzi
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Trachymyrmex.
Aromaticity0.04
Grand average of hydropathy-0.493
Instability index56.20
Isoelectric point8.58
Molecular weight280083.03
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06846
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.75|      11|      16|    1572|    1583|       8
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 1572- 1583 (17.66/14.06)	P.GIEIIPIAsSP
 1589- 1600 (19.09/ 9.52)	PsSITITPIA.GP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     445.55|     111|     122|    1299|    1413|       9
---------------------------------------------------------------------------
 1299- 1374 (99.09/37.41)	...................................................EG...R.SLPAVMNSLTSGSGSSNGSYNLNLG......SGA......NSTSASMLNP....LQLGALLGQAKNSLTSNSNTNERGK....K.......TRKRKIGTD
 1379- 1502 (128.68/55.51)	SPKRKSDGGD...SSAATEILL.ESSSSEN.STPLG.....TPTSrenlasET...RtSTPTSATSLTSGMDFSNLDTTDILD......KSAsdydldNSEKDSEIME....VQHSNAEQQQQQQQQQPQQEVEELI....K.iresssTRK......
 1503- 1567 (40.08/ 8.02)	SKKNRSGGGSeekKSSPTNIFVdETSSSGNkGLPVPpsvsiTPIS......CGnldQ.ASTTNYNSVLTGMG......................................................................................
 1847- 1926 (79.72/28.38)	........................................................R.RTSSVSSS..GGSGSGHQSPKTK.S......SSG......KMKQLEMISPgseaTQVSSL..QASGGSTPPSGPVDAAS....KsaiaaqqARNRKSSLN
 2041- 2104 (63.36/20.75)	.....SSSGS....MAAT.....SSSSSLS.S...........VA......SS.....SSSSSSSNVIT..GS.NGSPKTHTGlkpgvnSGP......ASKKPQTLQA....AQ............................................
 2139- 2186 (34.60/ 7.33)	.................................................................SATGGVG...GNPLSKSS......SSS.....kASGSPKT.......................SSGVTD.LSrgrdK.......PRISKSGDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.00|      44|     117|     156|     199|      10
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  156-  199 (75.06/46.34)	PSRTATNISRNISEHSTTTKVDASRSFK.LFHRDSLVSLH.HSMDI
  272-  317 (68.94/41.85)	PDNTLTSSAPLNSLYSGLPDIDSSRKRRgIYEHDITPQLDwHAPDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.89|      26|     117|    1011|    1038|      11
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 1011- 1038 (42.37/37.83)	HPMkLTYFV...SPYDLIDEENR.TYDTLnPD
 1129- 1158 (39.52/25.08)	HPL.LSLIIqhaSDGQLDCRNNRgLYVTL.PD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     198.94|      45|     121|    2196|    2240|      12
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 2196- 2240 (75.13/41.13)	DARKSSPSALREESESERAFKL.LAAHASISNLPP......SLPPQLMMEGL
 2245- 2262 (25.25/ 8.54)	DTKFQIP..............K.LSARANIAD...................A
 2263- 2285 (36.13/15.65)	DKNKSSD.............KL........SILPD......S..TKQTLDGL
 2315- 2366 (62.43/32.83)	DHSQNKPDNLSITTSAAGAMSLnLVGENTGLMLPPqstadsDVPTNLCIQPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.23|      16|     121|    1992|    2009|      13
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 1992- 2007 (27.19/21.22)	GGKSCVTKNASVDTKN
 2019- 2034 (26.04/11.17)	GIKITINKTRTKDSKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.61|      41|     121|     421|     486|      17
---------------------------------------------------------------------------
  435-  482 (58.24/68.26)	TGTTYSSEYSDGMISrGILKQDDYADALTydlveSKGNKsSYSDSTFS
 2386- 2426 (71.38/28.45)	TGQQFLGKIDDTSVG.GILSKSNVSDQLT.....SSGAK.SYGTMTSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.82|      15|      16|    1048|    1062|      22
---------------------------------------------------------------------------
 1048- 1062 (27.20/16.88)	SVTVCMEGSTGHKLP
 1065- 1079 (25.62/15.34)	SIITVNRSPTGKSTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.28|      16|      16|    1768|    1783|      23
---------------------------------------------------------------------------
 1768- 1783 (29.76/17.83)	PVPVPASASPKHGNTS
 1785- 1800 (27.52/15.66)	PKHGSSAASSGKPSMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.09|      10|     533|    1976|    1985|      24
---------------------------------------------------------------------------
 1976- 1985 (19.60/ 6.30)	GGGGSSSSSG
 2512- 2521 (20.49/ 6.94)	GGGGGGGGHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.62|      10|      16|    1633|    1642|      27
---------------------------------------------------------------------------
 1633- 1642 (16.61/ 7.61)	KSSSEDTKSG
 1651- 1660 (19.01/ 9.98)	KRKREDGPMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.35|      19|      24|    2554|    2572|      31
---------------------------------------------------------------------------
 2554- 2572 (41.17/18.54)	PPPPPPLPAPFP.PAASPSV
 2580- 2599 (32.19/12.77)	PAPSPRVIPPSPhSSASPCI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06846 with Med1 domain of Kingdom Metazoa
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