<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06834

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMRDTPMQRICSELTEKLLKSLDKEYNVVDIRAVVDVISTLEKTTVTKEVLEITRLGKHINELRRKTSNEALAKRAKDLVRRWRDMVLPTVHSTPNQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSISLTSNHWISSCSRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLQATNDEPGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSNQKNSQSLRKSLASSETSTGKTQKAAARLKSAENCRESPSPESCQDRLREDDRISGTTETCRSPLQQDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDATAEDLERLHVQCIEGLNGNFQPRLSMTTACSDGDERSNTRDGGNGVSSGLSNVDSVKSVHDNQTDNVEFREWHQMLARPSYQGEILNIMPYVIID
Length567
PositionUnknown
OrganismCyphomyrmex costatus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex.
Aromaticity0.02
Grand average of hydropathy-0.864
Instability index60.06
Isoelectric point8.17
Molecular weight62844.39
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06834
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.23|      19|      22|      97|     118|       1
---------------------------------------------------------------------------
  100-  118 (32.23/21.23)	ALNGAKEMALRNLKP...QSPA
  121-  142 (28.01/10.06)	ELKPHSPLSLKDATPlrvLSPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.57|      16|      24|     382|     405|       2
---------------------------------------------------------------------------
  382-  405 (18.68/25.28)	ETSTGktqkaaaRLK.......SAENCReSP
  408-  430 (24.89/11.96)	ESCQD.......RLReddrisgTTETCR.SP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.28|      28|      53|     146|     173|       3
---------------------------------------------------------------------------
  146-  173 (49.37/35.89)	HSDHSRSPNASSNNKQSISLTSNHWISS
  198-  225 (47.91/34.56)	HSSNKRLRKEESSKDQCQYYQSPHGTES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.98|      29|     244|     226|     259|       4
---------------------------------------------------------------------------
  228-  256 (46.17/24.84)	EEVKKQRLNGENISGNLNSQVPSPTLKER
  261-  280 (26.94/16.44)	..FAETSLQATN.......DEPGPKKRGR
  285-  311 (34.87/13.74)	KSAKRQSFLEDSVKEKLASISRNPKLK..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.35|      17|      22|     445|     465|       5
---------------------------------------------------------------------------
  445-  465 (27.66/25.24)	PPLDPSSidwgEDEERDDAEC
  468-  484 (32.69/17.66)	PPRDATA....EDLERLHVQC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06834 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RLSMTTACSDGDERSNTRDGGNGVSSGLSNVDSVKSVHDNQTD
2) SRNASPVLGTSNQNHVTEAVPRTHSSNKRLRKEESSKDQCQYYQSPHGTESTIEEVKKQRLNGENISGNLNSQVPSPTLKERISDCFAETSLQATNDEPGPKKRGRKKGSKSAKRQSFLEDSVKEKLASISRNPKLKTTQELLADLQARGSNCSPIGSANALPSQSVAEPPSTEDVLRGSNNEQVSKHLRCSNQKNSQSLRKSLASSETSTGKTQKAAARLKSAENCRESPSPESCQDRLREDDRISGTTETCRSPLQQDLTVEEILAKLPPLDPSSIDWGEDEERDDAECFPPPRDAT
3) TVHSTPNQPTLALNGAKEMALRNLKPQSPALRELKPHSPLSLKDATPLRVLSPALSVHSDHSRSPNASSNNKQSISLTSNH
495
175
89
537
473
169










Molecular Recognition Features






MoRF SequenceStartStop




1) FLEDS
292
296