<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06831

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYVIPTLEYFSQGGIEDREYVAENSTTLYGIVVYHAADCLPSPCTETLGPYSNPHKLLMVLDKLEMVGGKGESFANIGEGLATGLQCFEDLQLRREPNTASQKHCILICNSPPYQTMIQETYKFAGHTIEQLATIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPQNIASVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANAQGSALIAQLTQPPSSLGLNVAAFNQRLDVAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQQATMSMAAQPTHSQPGSQLTASCISQSVPTQVSQTVTASQQAPVSVSSITQQITHPQVQGNVSTGTVQNQQLVPRERQNIWQGIVEWIEKAKNPTDAQKQTRHVPCQVSANAKDGDPELKADTWPPKLIMQLMPKQLIGNIGGTYLKNSKSVVFHPTPCEALESLTKMMSAGFAGCVHFTTASTSPACEIKVLILLYTTDKKTYLGFIPNDQTAFVDRLRKVIQQQKTSQNASVRQTNPGPGNTIPAPMPTTGTQGGILMSQTNTMAMGGGQITQNVVSTVPPQTLTSTSGPQMTQMNMQNSGISGPQANTGAGGMIGQQRPPYDDIEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQQPQPQYSVRQVFGVQQQMVGPRGQIATRPMAPGNAQNQQFEDVSNYDFLG
Length879
PositionUnknown
OrganismCyphomyrmex costatus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex.
Aromaticity0.05
Grand average of hydropathy-0.514
Instability index53.19
Isoelectric point8.80
Molecular weight96068.47
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06831
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     314.77|      43|      43|     255|     297|       1
---------------------------------------------------------------------------
  192-  249 (28.26/ 6.21)	EKAGGDLQSS.Q..TKNYAK..dprhlvllrnynlkERPVSPQMG....G........nvHNTA.ATAAQI..P.lsPL
  269-  314 (64.40/23.11)	QQQGPPFRNQ.A..PQNIAS.V..............HQTVTPSMA....AP...mntarpPYNP.QIA...A.P...PN
  315-  350 (31.42/ 7.69)	YH..PPGVNI.AtrPRWM..................RPFIAPGAT....AP.............aNAQGS.A.L...IA
  351-  391 (44.38/13.75)	QLTQPP..SS.L..GLNVAA.F..............NQRLDVAGN....NV.........MAAN.QQQQQQQ.L...TQ
  392-  420 (30.30/ 7.16)	QQQQLRLTMQlQ..QQNV...................QQATMSMA....A......................qP...TH
  421-  477 (33.13/ 8.49)	SQPGSQLTAScI..SQSVPTqV..............SQTVTASQQ....APvsvssitqqITHP.QVQGNVS.TgtvQN
  478-  520 (43.50/13.34)	QQLVPRERQN.I..WQGIVEwI..............EKAKNPT.D....AQ.........KQTR.HVPCQVS.A...NA
  632-  666 (39.39/11.42)	QQQ......K.T..SQN.AS.V..............RQT.NPGPGntipAP.........MPTT.GTQGGI........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     115.83|      21|      21|     747|     767|       2
---------------------------------------------------------------------------
  747-  767 (37.67/17.32)	QHLRQTLEAAQQQEAQYKSQ.L
  770-  789 (30.56/12.50)	.NIQQNLEVAQQQEMQYKQQ.L
  792-  813 (25.58/ 9.11)	QQAQRGLNPAAMANQQANSQrL
  837-  854 (22.02/ 6.69)	..VRQVF.GVQQQMVGPRGQ.I
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.59|      24|      33|     132|     157|       4
---------------------------------------------------------------------------
  132-  157 (40.68/34.23)	TASQKHCILICNSPPYQtmIQETYKF
  167-  190 (40.91/26.98)	TIYQERNINISILSPRK..IPALYKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.04|      37|      55|      25|      64|       8
---------------------------------------------------------------------------
   25-   64 (55.84/54.14)	GAYLNDLKTNYVIPTLEYFSQGGiEDREYVAENSTTlyGI
   82-  118 (65.20/49.23)	GPYSNPHKLLMVLDKLEMVGGKG.ESFANIGEGLAT..GL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06831 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKNPTDAQKQTRHVPCQVSANAKDGDPELKA
2) GGGQITQNVVSTVPPQTLTSTSGPQMTQMNMQNSGISGPQANTGAGGMIGQQRPPYDDIEIARHQ
3) QQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQ
4) QQKTSQNASVRQTNPGPGNTIPAPMPTTGTQGGILMSQTNT
5) RPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPQNIASVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANAQGSALIAQLTQ
6) VAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQ
7) VSVSSITQQITHPQVQGNVSTGTVQNQQLV
499
677
780
633
224
372
452
529
741
829
673
354
404
481










Molecular Recognition Features






MoRF SequenceStartStop




NANANA