<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06828

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMETKVTSKTSSLKALLLRAWRERWTDLQWGINIKTTNLQILPRGVSGDVYNLADCILQQALVGPGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFYKPYCIVSLLEFLESIRVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKTLQSNPFIPYPSELVDKPASILQQMLNSDFLCAMMYLAKYDDKDLYIEVVKKCQEIETLLKTVPQTQKSVVLIDDSLKKLCNLEIESLCPEKTRMESITHCLQPLFAIQVLLNPSTETTVFVNQLLMVQRLKSYTNARLYCEIIRACLMCLHNVTGTFKESRWGAFMFLKVPHILKELHVANLNGYSLTVGESKFGFTSLRHLGDKKLEYSQDILDAFELLLQFTPLLDIMDTTGSCNYVECLLNELQKVNLVTEKQAKQISARREGTTVASSIPKIIVQAGQTLNGILRTLNVDYAKIQGLLKVLHHILTGKSFELMLAVATVLGKLKTFVTKLIKINECSKQINESVTDETATTRAMLFDVSFLMLCSIVQTYGSDIVLEEDGDSFFEQWVRECMPERNKLKSPQRMLQSVDSERVDALLAQINSPDPDFKSNNLKWHIACQSAMGAVQELLYAWESGVLSAGDVKRTLDGLRATACCLPVCAVAWLCAYMSITHQDALLKPMNMVQHFLTPLSGDEMQDNLKDRSSLMVQIIRKMQYNVHPPTQSKTKVLSMSHSIVSHQPILEQLESVWQNINQRGWINIQATKSLKSLLNTGDSLWFVTNIVKEVLKYRYQEELDQAVDLAFAIFHLDIENCTLDLINHIIPQYLYNSMQSDELVEPQSSILAKLCVYCIFSTLEYNNSNPYRGNKRVRHDLDTNDLDALGVSNKLLRLNETGENISMFSSQSPQAQGSSNGQKSVVILRDPLMTALNNLFIVFAFLAGRDGEVSQQTHFILQFLRLMVQCGKDRTCIVLQGMPQTLARVDKIHVDGLVRTKDDIIKSQVTDLFKAKNFEDVIIRAYKVREKLDALGCFRNIGIYIDTSQGPDATPDGVEVTFMVREMRRLVGGISTMVGNNEGSLIIGARAPNLFGRAERVQMEYSYGNKSSINFNVSAIKPFPQSLYNAVLTSTVFSTTHDFPWSGFKQNDKGLLFDMELNQTDTSKHNIQYEAAFRNISCSKLAAFRVREQCGPNLKSALRYIWTIDKRDCSIFPMAGSLMRLTTEMAGLGGDIGFLRNELAIQTNWSPHKYLTFQLGLQSGLLSAISNDMKISIADHFFLGGPLNLRGFDMRGCGPRYEGNSVGGEMYWAAALHVYTPLPFRPGRNSFGDLFRLHGFINGGNLSNFTYDNLYDENMKIFTENVRCAMGGGIAMKLGNIARIELNLVTPLLFMRSDVLQQFQFGIGLQYL
Length1378
PositionTail
OrganismCyphomyrmex costatus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex.
Aromaticity0.08
Grand average of hydropathy-0.055
Instability index39.23
Isoelectric point7.45
Molecular weight155244.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
outer membrane	GO:0019867	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06828
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     496.85|     165|     290|     897|    1074|       1
---------------------------------------------------------------------------
  897- 1074 (244.94/241.28)	PLMTALNNLFIVFAFLAGRDG....EVSQQT....HFILQFlRLMVQCG......KD.RTCIV...LQGMPQTLARVDkIHVDGlVRTKDDiikSQVTDLFKAKNFEdvIIRAYKVR...EKLDALgcFRNIGiYIDTSQGPDATPDGV...EVTFMVREMR.RLVGGISTMVGNNeGSLIIGARAPNLFGRAERVQmEYSYG
 1183- 1372 (251.91/194.25)	PMAGSLMRLTTEMAGLGGDIGflrnELAIQTnwspHKYLTF.QLGLQSGllsaisNDmKISIAdhfFLGGPLNLRGFD.MRGCG.PRYEGN...SVGGEMYWAAALH..VYTPLPFRpgrNSFGDL..FRLHG.FINGGNLSNFTYDNLydeNMKIFTENVRcAMGGGIAMKLGNI.ARIELNLVTPLLFMRSDVLQ.QFQFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.07|      40|      93|     364|     408|       2
---------------------------------------------------------------------------
  364-  408 (62.87/45.25)	IL..DAFELLLQFTPLLDIMDTtgscnYVECL..LNELQK.VN.LVTEKQA
  459-  504 (48.21/24.85)	ILtgKSFELMLAVATVLGKLKT.....FVTKLikINECSKqINeSVTDETA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     257.87|      89|     589|      10|     122|       3
---------------------------------------------------------------------------
   10-  113 (125.56/126.93)	SSLKALLLRAwRERW..TDLQWGInIKTTNLQILPRGV..SGDVYNL..ADCILQqaLVgpgpNQLVLSYLKHSL.SSQLV.SYAAVLQRISkydafykPYCIVSLLEFLES
  738-  834 (132.30/75.80)	KSLKSLLNTG.DSLWfvTNIVKEV.LKYRYQEELDQAVdlAFAIFHLdiENCTLD..LI....NHIIPQYLYNSMqSDELVePQSSILAKLC.......VYCIFSTLEYNNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.15|      19|     610|     543|     564|       7
---------------------------------------------------------------------------
  543-  564 (31.89/26.16)	VRE.CMPErnkLKSPQRMLQSVD
 1156- 1175 (33.26/19.02)	VREqCGPN...LKSALRYIWTID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.28|      17|      93|     187|     203|       9
---------------------------------------------------------------------------
  187-  203 (29.94/19.30)	LAKYDDKDLYIEVVKKC
  281-  297 (31.34/20.53)	LKSYTNARLYCEIIRAC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06828 with Med24 domain of Kingdom Metazoa
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