<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06826

Description XK-related protein
SequenceMYNINRERSSVTWVALALQAVWRSGMLLSRVVVLVLALIFLKAWFFLFLGLHWLSMTVWVILQKTKFCSTAWEERIYNCVIGLIYCFDFFNLRDDRSRYRVLIFYSVVAAQNLFFLIMYILHFGGTIESITMIMIVSVIIGFMLISLASMSLYYGKFHPSKTTTNISRNISEHSTITKVDASRSFKLFHRDSLVSLHHSMDISPKTEEVPTDKQSLLTNIAQISDCVEEGIVNCNYSSENESNASALRLSTECERPHSRVGVKHKEEVTSVNDNPDNVTTSSAPLNSPYSGLPDIDSSRKRRGIYEHDITPQLDWHAPDILNINLDKLGFDNCERSNSLTLDSCSKVIGALDIIKNREKLTTPTPLESSRIFDIEKQRDETMSCVTSIHDYENVCPLGIARPPWCIRSWKGYTDIETYIHDDSVVRDRRRDTLTSTTGTTYSSEYSDGMISRGILKQDDYADALTYDLVESKGNKSSYGDSTFSTSADDQNASLYVAKPVVFDDRGGMLALDTILEERDDLSDEKFQHGTEPSRDSASTLVSTIDQIRRYTADNSPRHIYHTTGTHWEDLNPKNLMTQARFAKVLFNNDLRNASTTTGSIDLTAWDVEKREIDAFREFVRCCAIESIKKTPLIDAVLSDSPILDKASKLMRQVTFADCKNDFDTNESDLYVEMSPLVSVENGDNLCQARSIDAKTAETESVIKRNTLPTVSKKSPNKENLSPSLSNNNRQINNIDDNRDNNDSHAWTIEKDEKTDKSLCNMRFNLKEKRHLFLEQVLSPVPKLWNKPGQPSPGGGPASDKGKEWQMEFLMEKLRSKSSTYKPLVETAKNMRMAMLDKRFAIDSIEKNQLQKCLDTLQHSIKVTSFQSMVERLESLARQLGLKFMMSGPPGTEIFISSDMFFLEVLLEPPSGLVRDVKIHHEGKSEQQSCEALASALSRGDFVDFTTQLEGLASIYQLNADKKVKCKAFSALQSLEADLGVLAQLQTFMKEPFNLVHKSPVGILERRRGGHPMKLTYFVSPYDLIDEENRTYDTLNPDTIIKRKIGHSVTVCMEGSTGHKLPTSSIITVNRSPTGKSTPSYAPLTSTNSSMLPACFVLKLVKKMPICMELVKRIQKVTELECGDISAPHPLLSLIIQHASDGQLDCRNNRGLYVTLPDQQHCYFMTENKNMEGVLVCSIPFTHPAHVPQILVYLRQQALFNCLIASCVRPMARQDPEHTTILEVSALSWQHISVSVEHPYEETMATAELDLTDISTLKCRLYGVSMTTNAEQTSDLSGRVLQRCLSIPLTMRMLLKIWEGRSLPAVMNSLTSGSGSSNGSYNLNLGSGLPVPPSVSITPISCGNLDQASTTNYNSVLTGMGLERRPGIEIIPIASSPSQTNLPSSITITPIAGPTSSPKTSGLTSATEDRQRSERKSGGGKSSSSSSSKSSSEDIKSGGNKLEKRRKRKREDGGPMGPPEKVPSSGKQQDPLSKPVSVSIKPSPEQSPPSGGSTGVGLSCSSSRPTSPAAVRKFSPSPTHSSSLATLVGKSSPTLKAGQSAAATCGKPVQSPKHSPVYGSTVSVPVPVPASASPKHGNTSSPKHGSSAASSGKPSMSALKSAANSPSSKTSSSSSSDSTTTSSKVKSSSSSSSKDSSGRGDKDRRTSSVSSSGGSGGGHQSPKTKSSSGKMKQLEMISPSSEAQVSSLQASGGSTPPSGQVDAASKSAIAAQQARNRKSSLNAVIDKLKNAQHCTETDVCGNGGSNVKGSGSSGLSGTGGMSSAGQKEKNIGGGGSSSSSGGKTIGEGGKSCVTKNASVDTKNPAEYMVKHSSDGIKITINKTRTKDSKQAANLKLSSSGSMAATSSSSSLSSVASSSSSNVIIGSNGSPKTHTGLKPGVNSGPASKKPQTLQAAQKMLPTKMMLAAGMKSTISSGTTNTGSGAGITATTTGGIGGNPLSKSGSSKASGSPKTSSGVTDLSRGRDKPRIPKSGDKGIFASKGLGDARKSSPSALREESESERAFKLLAAHASISSLSPSLPPQLMMEGLMKQLDTKFQIPKLSARANVADADKNKSSDKLSVLSDSSKQTLDGLKQEQGKIAGLSNVTVSISKSSLPDDQSRRDHSQNKSDNLSITTSATGAMSLNLVGENTGLMLPPQSTADSDVPTNLCIQPMDNEPSRDSCKDLGMRQTSTGQQFLGKMDDTSAGGILSKSNVSDQLASSGAKSYGTMTSTSTASSGAIVTESLNLSTKPADQAVLQTKYNKITVEEKKQQQTSSASLSSTSSTSSSSSSSIFSSLTSVGTSSDGNSVMTSDSGSGGGSGGGEQEVAAAAAAAAAEMLLDFSAANKDSLTKGSHGLPASLTQHHLTTIPERAMTQAAQTVRRNTPPPPPPPPPLPAPFPPAASPSVSVHIVKSPAPSPRVIPPSPHSSASPCITDDELMDEALVGMGK
Length2430
PositionMiddle
OrganismCyphomyrmex costatus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Cyphomyrmex.
Aromaticity0.05
Grand average of hydropathy-0.433
Instability index54.55
Isoelectric point8.75
Molecular weight260301.15
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-UniRule
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06826
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.68|      28|      31|    1470|    1498|       4
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 1470- 1498 (45.07/18.53)	PLSkPVSV.SIKPSPEQSPPSGGSTGVGLS
 1504- 1530 (32.37/ 8.75)	PTS.PAAVrKFSPSPTHS..SSLATLVGKS
 2290- 2306 (27.24/ 6.09)	VM.............TSDSGSGGGSGGGEQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.74|      13|      15|    1754|    1766|       5
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 1754- 1766 (20.01/ 6.12)	LSGTGGMSSAGQK
 1770- 1782 (23.73/ 9.07)	IGGGGSSSSSGGK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     311.67|      57|     429|    1406|    1462|       8
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 1406- 1456 (73.89/27.59)	.........................TEDRQRSERKSGGGKSSS................SSSSK......SS.SEDIKSGGNKLEKRRKRKR.EDGGPMG
 1568- 1603 (41.30/11.85)	PASAS.P................khG...NTSSPK.HGSSAAS................SG..K......PS.MSALKSAAN..................
 1641- 1671 (43.35/12.84)	..........................KDRRTSSVSSSGGSGGG................HQSPK......T......KSSS...............GKMK
 1672- 1717 (49.70/15.91)	QLEMIsP..................SSEAQVSSLQASGGSTPP................SGQVD......AA.SKSAIAA....QQARNRK.........
 1835- 1882 (45.35/13.81)	.................................LSSSGSMAAT................SSSSSlssvasSS.SSNVIIGSNGSPKTHTGLK..PGVNSG
 1883- 1975 (58.08/19.96)	PASKK.PqtlqaaqkmlptkmmlaaGMKSTISSGTTNTGSGAGitatttggiggnplskSGSSK......ASgSPKTSSGVTDLSRGRDKPRiPKSGDKG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     414.05|     138|     151|     234|     379|       9
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  234-  379 (215.75/144.14)	CNYSSENESNASALRLSTE..CERP.HSRVGVK...HKEEVtsVNDNPDNVTTSSAplNSPYSGlpDIDSSRKRRGIYEHDitPQLDWHAPDILNINLDKLGFDNCERSNSLTLDSCSKVIGALDIIKNR.EKLTTPTPLE.....SSRIFD..IEKQRD
  384-  535 (198.30/112.65)	CVTSIHDYENVCPLGIARPpwCIRSwKGYTDIEtyiHDDSV..VRDRRRDTLTSTT..GTTYSS..EYSDGMISRGILKQD..DYADALTYDLVESKGNKSSYGDSTFSTSADDQNASLYVAKPVVFDDRgGMLALDTILEerddlSDEKFQhgTEPSRD
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.53|      27|     429|     849|     896|      10
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  849-  876 (40.67/52.93)	LQKClDTLQHSIKVTSFQSMVERLESLA
  926-  952 (44.86/15.64)	QQSC.EALASALSRGDFVDFTTQLEGLA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.98|      38|      73|     680|     722|      11
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  680-  722 (51.23/56.78)	ENGD.NLCQARsIDAKtaETESVIKRNTLPTVSK..KSPNKEnlSP
  752-  792 (59.75/44.23)	EKTDkSLCNMR.FNLK..EKRHLFLEQVLSPVPKlwNKPGQP..SP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.00|      10|      21|    2373|    2382|      12
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 2373- 2382 (23.08/12.57)	PPPLPAPFPP
 2396- 2405 (20.92/10.46)	PAPSPRVIPP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     131.38|      36|      36|    2031|    2066|      13
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 1984- 2012 (36.23/15.22)	DARKSSP..SA.LREE..S.........E.SER.AFKL..LAAHASI..................
 2013- 2050 (24.81/ 7.94)	.........SS.LSPSlpPqlmmeglmkQ.LDT.KFQIPKLSARANVA...............DA
 2051- 2104 (34.19/13.92)	DKNKSSDKLSV.LSDS..S........kQtLDGlKQEQGKIAGLSNVTvsisksslpddqsrrDH
 2105- 2143 (36.15/15.17)	SQNK.SDNLSItTSAT..G..amslnlvG.ENT.GLMLPPQS....TA...............DS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.64|      19|     429|    1301|    1319|      15
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 1301- 1319 (35.30/22.19)	SLPAVMNSLTS..........GSGSSN..GS
 1719- 1749 (22.34/10.40)	SLNAVIDKLKNaqhctetdvcGNGGSNvkGS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.50|      38|     429|    1787|    1829|      16
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 1787- 1826 (57.03/46.08)	GGKS..............CVTKNASVDTKnPAEYMVKHSSDGiKITINKTRTKD
 2203- 2254 (52.47/23.73)	GAKSygtmtststassgaIVTESLNLSTK.PADQAVLQTKYN.KITVEEKKQQQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.92|      23|     138|     587|     609|      17
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  587-  609 (39.13/23.85)	NNDLRNASTTTGSIDLTAWDVEK
  728-  750 (41.79/25.99)	NRQINNIDDNRDNNDSHAWTIEK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.87|      46|     429|     178|     226|      18
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  178-  226 (74.09/57.72)	KVDAsrsFKLFHRDSLV.SLHHSMDISPKTEEVPT.DKQSLLTNIAQISDC
  611-  658 (70.78/46.98)	EIDA...FREFVRCCAIeSIKKTPLIDAVLSDSPIlDKASKLMRQVTFADC
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.35|      16|      21|    1239|    1259|      19
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 1239- 1254 (26.26/30.77)	YEETMATAELDLTDIS
 1261- 1276 (27.09/13.65)	YGVSMTTNAEQTSDLS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.65|      12|      15|    1056|    1067|      21
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 1056- 1067 (21.00/ 9.54)	TGHKLPTSSIIT
 1073- 1084 (21.65/10.09)	TGKSTPSYAPLT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06826 with Med1 domain of Kingdom Metazoa
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