<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06820

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYVIPTLEYFSQGGIEDREYVAENSTTLYGIVVYHAADCLPSPCTETLGPYSNPHKLLMVLDKLDLSIIIISSRMVGGKGESFANIGEGLATGLLCFEDLQLRREPNTASQKHCILICNSPPYQTMIQETYKFAGHTIEQLATIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQPPSSLGLNVAAFNQRLDVAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQQNVQQATMSMAAQPTHSQPGAQLTASCISQSVPTQVSQTVTASQQAPVSVSSITQQITHSQAQGNVSTGTVQNQQLVPRERQNIWQGIVEWIEKAKNPTDAQKQTRHVPCQVSANAKDGDPELKADTWPPKLIMQLMPKQLIGSIGGTYLKNSKSVVFHPTPCEALESLTKMMTAGFAGCVHFTSASSSPACEIKVLILLYTIDKKTYLGFIPNDQTAFVDRLRKVIQQQKTSQNASVRQANPGPGNTIPAPMSTTGTQGGILMSQTNTMAMGGGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGINGPQANTGAGGMIGQQRPPYDDIEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQQPQPQYSVRQVFGVQQQMVGPRGQIATRPMAPGNAQNQQFEDVSNYDFLG
Length889
PositionUnknown
OrganismAtta colombica
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Atta.
Aromaticity0.05
Grand average of hydropathy-0.482
Instability index52.20
Isoelectric point8.88
Molecular weight97055.66
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06820
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     180.00|      34|      35|     288|     321|       1
---------------------------------------------------------------------------
  289-  321 (53.43/18.43)	.PPQ....NITS....VHQTVTPSMAAPMNTARPPYNP.QIAA
  326-  357 (33.26/ 8.61)	HPPG...vNIATrprwMRPFIAPGATAPANT........QGSA
  364-  400 (28.11/ 6.11)	QPPSslglNVAA....FNQRLDVAGNNVMAANQQQQQQ.QLT.
  413-  439 (35.47/ 9.69)	.QQQ....NV........QQATMSMAAQPTHSQP..GA.QLTA
  718-  749 (29.74/ 6.90)	QNSG...iNG........PQANTGAGGMIGQQRPPYDDiEIAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.62|      24|      29|     190|     216|       2
---------------------------------------------------------------------------
  167-  201 (30.84/11.88)	AGHTIEQlatiYQERNinisilsPRKIPAL..YKLFE
  203-  232 (30.77/19.39)	AGGDLQS....SQTKN...yakdPRHLVLLrnYNLKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.46|      19|      19|     760|     778|       3
---------------------------------------------------------------------------
  760-  776 (26.11/10.23)	......RQTLEAAQQQEAQYKSQ
  777-  798 (30.14/12.97)	LE.vniQQNLEVAQQQEMQYKQQ
  799-  821 (24.21/ 8.94)	LEaqqaQRGLNPAAMANQQANSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.18|      16|      28|     440|     467|       4
---------------------------------------------------------------------------
  452-  467 (26.74/ 6.01)	QTVTASQ.QAPVSVSSI
  469-  485 (24.44/15.82)	QQITHSQaQGNVSTGTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.52|      16|      18|     252|     268|       6
---------------------------------------------------------------------------
  252-  268 (25.53/14.53)	QIPlSPLQSNDSPNTNQ
  272-  287 (31.99/14.92)	NIA.PPNQQQGPPFRNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06820 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGQITQNVVSTAPPQTLTSTSGPQMTQMNMQNSGINGPQANTGAGGMIGQQRPPYDDIEIARHQ
2) QQEMQYKQQLEAQQAQRGLNPAAMANQQANSQRLMRPVSTNNLGLRHLLQ
3) QQKTSQNASVRQANPGPGNTIPAPMSTTGTQGGILMSQTNT
4) RPVSPQMGGNVHNTAATAAQIPLSPLQSNDSPNTNQVQQNIAPPNQQQGPPFRNQAPPQNITSVHQTVTPSMAAPMNTARPPYNPQIAAPPNYHPPGVNIATRPRWMRPFIAPGATAPANTQGSALIAQLTQ
5) VAGNNVMAANQQQQQQQLTQQQQQLRLTMQLQQ
6) VSVSSITQQITHSQAQGNVSTGTVQNQQLV
688
790
643
233
382
462
751
839
683
364
414
491










Molecular Recognition Features






MoRF SequenceStartStop




NANANA