<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06773

Description Cell cycle control protein Cwf15
SequenceMTTAHRPTFDPVCTSIICSAHEAHCNRHKERRPSAALRTINVFSRLTHTLRHGKWFADRVRSSLTCPSQFGQGSEVETQQRDLRAELLQAEAAHFAKKNGVPVDEPKVETATPKRQLEGGSPGDDAKTEEEDPEAKRRRILEETRDIDADSDESEDDSSEDESDDEEDEAAELMRELEKIKKERLEQKEKEERERAAQEEEQREVDIARGNPLLNPQDFNVKRRWDDDVVFKNQARGTEDRRGKEFVNTESTSHTSTAVETYQLDVESTALVRAAEDILALTRTMKETWLFGKLDTLGEDEADVKRREELEMNAEAIQKAIEDGGFLKAAK
Length331
PositionHead
OrganismAspergillus luchuensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.04
Grand average of hydropathy-1.077
Instability index58.86
Isoelectric point4.86
Molecular weight37719.96
Publications
PubMed=27651094

Function

Annotated function Involved in pre-mRNA splicing.
ECO:0000256	ARBA:ARBA00003777
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
spliceosomal complex	GO:0005681	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
mRNA splicing, via spliceosome	GO:0000398	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP06773
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.82|      13|     168|     130|     142|       2
---------------------------------------------------------------------------
  130-  142 (22.87/13.01)	EEDPEAKRRRILE
  166-  178 (21.95/12.20)	EEDEAAELMRELE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.45|      10|     168|      27|      36|       3
---------------------------------------------------------------------------
   27-   36 (17.83/ 8.10)	RHKERRPSAA
  188-  197 (16.62/ 7.10)	KEKEERERAA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP06773 with Med22 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) CPSQFGQGSEVETQQRDLRAELLQAEAAHFAKKNGVPVDEPKVETATPKRQLEGGSPGDDAKTEEEDPEAKRRRILEETRDIDADSDESEDDSSEDESDDEEDEAAELMRELEKIKKERLEQKEKEERERAAQEEEQREVDIARGNPLLNPQDF
66
219

Molecular Recognition Features

MoRF SequenceStartStop
1) KTEEEDPEAKRRRILEETR
127
145