<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06750

Description Mediator of RNA polymerase II transcription subunit 25 (Fragment)
SequenceGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGLRAPQPQPQGAVGASAATGQPQPQGATQAPTGAPQGPPGAAPGPPPSGPIL
Length205
PositionUnknown
OrganismMus musculus (Mouse)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Muridae> Murinae> Mus> Mus.
Aromaticity0.06
Grand average of hydropathy-0.431
Instability index34.75
Isoelectric point9.82
Molecular weight22372.57
Publications
PubMed=19468303

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06750
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.97|      21|      24|     156|     179|       1
---------------------------------------------------------------------------
  156-  179 (34.48/18.57)	RAPQPQPQGAVGasAATGqPQPQG
  182-  202 (44.49/16.32)	QAPTGAPQGPPG..AAPG.PPPSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.46|      18|      24|      55|      72|       2
---------------------------------------------------------------------------
   55-   72 (33.81/22.11)	LTTLGPLFR...NSRMVQFHF
   77-   97 (28.65/17.81)	LESLKGLYRimgNGFAGCVHF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.99|      25|      74|      25|      51|       3
---------------------------------------------------------------------------
   25-   40 (23.52/10.27)	...........................................................PC...........QVYVNHG..ENLKTEQ
   43-  115 (15.35/ 9.57)	QKLIMQLIPqqllttlgplfrnsrmvqfhftnkdleslkglyrimgngfagcvhfphtaPC...........EVRVLM....LLYSSK
  116-  151 (27.12/ 9.98)	KKIFMGLIP....................................................ydqsgfvngirQVITNHKqvQQQKLEQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06750 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HKQVQQQKLEQQRGLRAPQPQPQGAVGASAATGQPQPQGATQAPTGAPQGPPGAAPGPPPSGPIL
141
205










Molecular Recognition Features






MoRF SequenceStartStop




NANANA