<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06749

Description Mediator of RNA polymerase II transcription subunit 25 (Fragment)
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEELRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKPVLGAEPYPDPARMSNSLSLLPANGIPRKLSSGIVKCRCLLRTSGRNPHLEFWEAPRPSLLHIRDGAYEDSTTFGQMFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPADVSQDPRHMVLVRGLVLPVGGSSTSGSLQTKQAVPLPPAPASAATLSAAPPQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKSQKAGLGPRFSPINPLQQAAPGVGPPFSQAPAPPLAPVPPGAPKPPPASQPSLVSTVAPGPVLAAPAQPGAPSLAGTVTPGGVNGPSAAQLGGPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIF
Length599
PositionUnknown
OrganismMus musculus (Mouse)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Muridae> Murinae> Mus> Mus.
Aromaticity0.07
Grand average of hydropathy-0.088
Instability index49.65
Isoelectric point8.53
Molecular weight63378.13
Publications
PubMed=19468303

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06749
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.08|      17|      19|     378|     396|       1
---------------------------------------------------------------------------
  376-  392 (29.98/ 9.44)	LG........PRFSPINPLQQAAPG
  393-  417 (21.10/ 7.90)	VGppfsqapaPPLAPVPPGAPKPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     198.65|      50|      66|     158|     207|       2
---------------------------------------------------------------------------
   32-   69 (36.60/12.76)	..........FEELRK........HYllPA..............IEyfNGGPPAETDFG.............GDyGGTQYSLV
  158-  191 (51.30/20.23)	........................PR..PSLL..........H.IR..DGAYEDSTTFGQM.FM........GG.GGESCSLI
  192-  260 (58.01/23.64)	AEGLSTALQLFDDFKKmreqigqtHR..VCLLicnsppyllpA.VE..STTYSGCTTESLVqKI........GE.RGIHFSIV
  261-  316 (52.73/20.96)	SPRKLPALRLL..FEK.......aAP..PALL..........EpLQ..QPA.DVSQDPRHM.VLvrglvlpvGG.SSTSGSL.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.46|      19|      19|     426|     444|       3
---------------------------------------------------------------------------
  426-  444 (35.99/15.24)	TVAPGPVLAAP..AQPGAPSL
  447-  466 (28.48/10.56)	TVTPGGV.NGPsaAQLGGPAL
  476-  493 (25.99/ 9.00)	LLAWSGVLEWQ..EKPKPAS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.62|      18|      19|     320|     337|       4
---------------------------------------------------------------------------
  321-  340 (28.09/12.53)	AV.PLPPAPASAATLSAAppQ
  341-  359 (30.52/14.32)	ALpPVPPQYQVPGNLSAA..Q
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06749 with Med25 domain of Kingdom Metazoa
Unable to open file!