<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06710

Description Serine/threonine-protein kinase SSN3 (Fragment)
SequenceSHRSVSSKYAILGFISSGTYGRVYKAQSLEEDGRVHAIKKFKPDKEGDVVTYTGISQSAIREIALNREINHENIVALKEVILEEKSIYMVFEYAEHDFLQIIHHHSQTIRTPISHVVLKSLIYQLFNGLLYLHSCHILHRDLKPANILITSNGIVKIGDLGLARLCYEPLQPLFAGDKVVVTIWYRAPELLMGAKHYNKAIDCWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQRDQLLKIFEVMGTPDEKQWPGVFDMPEYPNMKRLDPYTNRLQEWCHSRIRSHLGYELLSQLFAYDPDKRLTAKEALQHKWFYEDPKPTWNAFETVPVHQFPPHRRITQDEAPSMMPLPAQNTSHQGAAGAGAAGHNGGGHVAGPFGQPHSKPGSTTSFASVGVSGGYAGQATATGGNGHARKKARLG
Length423
PositionKinase
OrganismLeucoagaricus sp. SymC.cos
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Agaricaceae> Leucoagaricus.
Aromaticity0.09
Grand average of hydropathy-0.356
Instability index42.85
Isoelectric point8.85
Molecular weight47238.42
Publications









Function






Annotated function


GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06710
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.14|      21|      35|     354|     374|       1
---------------------------------------------------------------------------
  354-  374 (40.78/24.52)	PAQNTSHQ..GAAG..AGAAGHNGG
  388-  412 (29.37/15.86)	PGSTTSFAsvGVSGgyAGQATATGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.46|      13|      15|     165|     178|       2
---------------------------------------------------------------------------
  165-  178 (21.24/18.25)	LCYEPlQPLFAGDK
  183-  195 (24.22/15.49)	IWYRA.PELLMGAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.66|      33|      34|     278|     311|       3
---------------------------------------------------------------------------
  278-  311 (53.82/35.12)	QEWCHSRIR.SHLGYELLsQLFAYDPDKRLTAKEA
  314-  347 (57.85/33.73)	HKWFYEDPKpTWNAFETV.PVHQFPPHRRITQDEA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06710 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FETVPVHQFPPHRRITQDEAPSMMPLPAQNTSHQGAAGAGAAGHNGGGHVAGPFGQPHSKPGSTTSFASVGVSGGYAGQATATGGNGHARKKARLG
328
423










Molecular Recognition Features






MoRF SequenceStartStop




1) ARKKARLG
416
423