<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06709

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMAADFWASSHHKRWIVDRATVRRARAVDLLYVDDPVYLEYFAIYFANVITKLGKKLGLRQRVIATATVFFRRFYLKNAYCETDPFLVIAACCYVAAKAEESPIHIKTVISEARSLFSQEMYGVKNFPSDNSKLAEMEFYLVDDLECDLTVFHPYRTLLTLCKKESELDPSATPAEEGEAGEVGSSGFSGLSGAGNLGVGIGADDGPRYWGTGEGKLELSTGALQTAWFIINDTYRSDICLLYPPHLIAISAIYLTFILHNPTRSTITPLLSSSSSSSPLSSSTTPTQSTDEPQKPRRSSRNTSQAHSSSTPSQQSGEKKTQDPITFLSELSVSLPLISTISQEIISLYTLWDRYKEDAHPEAKTSAAHASHTYTTTSIIITPSFLSGLLATMRELRVADVTRGPGVAVNKMLERTQAAG
Length419
PositionKinase
OrganismLeucoagaricus sp. SymC.cos
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Agaricaceae> Leucoagaricus.
Aromaticity0.09
Grand average of hydropathy-0.167
Instability index45.43
Isoelectric point6.09
Molecular weight46053.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06709
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.15|      26|      64|     290|     315|       1
---------------------------------------------------------------------------
  261-  291 (26.64/11.95)	...P..................................TRstitpllsSSSSSSPLSSSTTPTQSTDE
  292-  317 (47.92/26.95)	PQKP..................................RR........SSRNTSQAHSSSTPSQQSGE
  320-  377 (18.59/ 6.27)	TQDPitflselsvslplistisqeiislytlwdrykedAH........PEAKTSAAHASHTYTTTS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.00|      11|      17|     192|     202|       5
---------------------------------------------------------------------------
  192-  202 (19.90/14.37)	GAGNLGVGIGA
  212-  222 (19.11/13.51)	GEGKLELSTGA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06709 with CycC domain of Kingdom Fungi
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