Description | Mediator of RNA polymerase II transcription subunit 19 |
Sequence | MSFHPRTPQSPSQFSPATSDLTSSMNSSAPSTATTLPTPAHSVNGSASQPSDMSQDIVMGDDSPHKRKRPLEDLGDRDQKKAHIEDSKTGIEALHLDVGEKYLLCQTPHHERLPRITEDLFEMFNLSGIAAEVAREKPNGEKNALRKTYKGQIKKLGILGRFDSVAQDWDAPREKDGESSDKKREVYHGFRELLEIPDAEYWGTRNDPITSGLSGTVKSMLNRATTMAKGPLPVKDWDSSVLGDLTPGSIEALRQGLGGKVTAPGTPSATTPNPFARKQQQGPQGAVRPQRTTKKRGYGDNSFEGYGEGFPDDGYSTGDGDDRGGQKRRKKDNGNGQTFPNTMRPQGYGSSAVGA |
Length | 355 |
Position | Head |
Organism | Colletotrichum salicis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum> Colletotrichum acutatum species complex. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.958 |
Instability index | 44.94 |
Isoelectric point | 7.80 |
Molecular weight | 38541.18 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364151 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP06655 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 230.10| 70| 157| 36| 108| 1 --------------------------------------------------------------------------- 36- 108 (119.05/67.91) LPTPAHSVNGSASQP..SDMSQDI.VMGDDSPHKRKRPLEdlgDRDQKKAHIEDSKTG.IEALHLDVGEKYLLCQTP 194- 267 (111.05/57.09) LEIPDAEYWGTRNDPitSGLSGTVkSMLNRATTMAKGPLP...VKDWDSSVLGDLTPGsIEALRQGLGGKVTAPGTP --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 79.76| 23| 47| 277| 299| 2 --------------------------------------------------------------------------- 277- 299 (41.39/18.51) RKQQQGPQGAVRP.QRTTKKRGYG 326- 349 (38.37/16.73) QKRRKKDNGNGQTfPNTMRPQGYG --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 59.81| 17| 36| 135| 151| 3 --------------------------------------------------------------------------- 135- 151 (29.89/21.75) REKPNGEKNALRKTYKG 173- 189 (29.92/21.79) REKDGESSDKKREVYHG --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) FPNTMR 2) GYGEGFPDDGY 3) QKRRKKD | 339 305 326 | 344 315 332 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab