<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06650

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMPLMLENGMNGAMQVDQLDVDDLFGDGVGGLSLHTARPPTKQLRQRIDELRTRGCCQGVAWSRSGAIASVSPDGKTLEARFLRSHPDNGDWGLSEPTKVDLISINPSSPIIHLAWASTASPELAVIDATGRVAILTYSITLNRPFATRKWDHDPSDDLHAIVGSYWLPLAPQSKQYWVSHGPAIKDKTQYKYESSFVRAGGPWHPNPSKSALLCVTTNGHLKMFWAQNNNKIEETSLELESVNSSDDLITHAALHRYLWVALATTNKQLRLVKVGIHWGLPQSQSDTKPPPGSQALNPTLHEKHIAISSWLPSGPSTTPVDSAATQLTHLEILPSVMDPNGQGAPLVILAVRTYVPTPNTPYQETQSIIDKWEVSNEQPQSLHPAFEQLGSRRNSTGTAPAPTCRLKKCDPVIINKAVVGLHTIQYGNVVCLAFGDGSVEYRDRYTLQEVYNEMNLDRVMTLNQVGFTLQDDSPCLQMAFSPTNCSVVKIQDDGKVKWSRLHHPLGDIGNSNQDAPYAATLAALTVAASTATFNSINYDDILAVARPFADKKRFTFDWINEIVRMLKVPVDYSEDTHHDSLVRNSSLQMCLSILNHLGYKGMFQPRTFGGKFAMLALNARNVVILITIASNTPVNIREKLSPLDEHEVVDALAGCAKWSLDLLAWLTDSLFALLDDPQFLALLTPQRFSEMSAYLQSRSDVSLHLLLCSSTRGFLSAVCRRILHLEILSNRAIEFYERRAAMQNATDPSSQAKGLHVVLYKAYQKMQRVTSSSLIKVQEFDRLLTVLNNDIRTAYQTSLASLASKNPPGGGAGGQKAVDAQIKNAQVHCELNMLLASSPPPAFLGVLLKFFNTDLRAYRGLADPSKLFFADYDLLEVDDDRRTLAARKAKSRFIDVFKRVELVGPPPTSARAGGGGSSGGGGGNSASASTGSGKEAEDAKTAQWRRCVRCSAVMEDVFGSRPGFTFVLAQQRKCSCGGHWGLLPRGSLIS
Length990
PositionTail
OrganismColletotrichum salicis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum> Colletotrichum acutatum species complex.
Aromaticity0.07
Grand average of hydropathy-0.223
Instability index42.13
Isoelectric point8.03
Molecular weight108501.15
Publications









Function






Annotated function

Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors. 


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06650
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.49|      11|      16|     661|     671|       1
---------------------------------------------------------------------------
  661-  671 (20.30/10.77)	DLLAWLTDSLF
  678-  688 (20.19/10.67)	QFLALLTPQRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.45|      16|      17|     526|     541|       2
---------------------------------------------------------------------------
  526-  541 (26.62/15.91)	VAASTATFNSINYDDI
  544-  559 (29.82/18.65)	VARPFADKKRFTFDWI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     423.85|     109|     110|     115|     224|       3
---------------------------------------------------------------------------
   78-  192 (169.25/94.13)	EARFLRShpdNGDWGlSEPTKVDLISINPSSPiIHLAWAST......ASPEL.AVIDATGRVAILTYSITLNRPFATRkW..DHDPSDDLHAI.VGSYW.LP.LAPQSKQYWVSHGPAIKDKTQYKY
  193-  304 (156.39/83.25)	ESSFVRA...GGPWH.PNPSKSALLCVTTNGH.LKMFWAQNnnkieeTSLEL.ESVNSSD..DLITHA.ALHRYL....WvaLATTNKQLRLVkVGIHWgLP.QS.QSDTKPPPGSQALNPTLHEKH
  307-  381 (98.22/49.64)	ISSWL.P...SGP.S.TTPVDSAATQLT...H.LEIL...............pSVMDPNGQGAPLV..ILAVRTYVPT....PNTPYQETQSI.IDKWE.VSnEQPQS...................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06650 with Med16 domain of Kingdom Fungi
Unable to open file!