<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06643
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MANPNDPPLDEIQWRAPDIAASMQGIHSNSVLFYFAESPFFDRQSNNAVITNQAMFNPALLKNLATREAFESELDKMAGLEFRVLHAPADMVMGTGVWTIVKQTRQKNLDRGRMEAKPLAYYFVVGENIYQAPTLGDLLSSRIESIAESMRKVLPAADSVRKWTPSLGHVYTQPTPPSALSRAKDGGAAAAAAAAADTPAAEGAVNGSKTSTGANKSTNSKKDSTANALDRLAEESFAIHMRHGGDYFDENPITGRPGDFHFASTGRKDKIAPPPPPSQSQSSSSSQQASQAQPKPVINTKLAEEAKKEGKEGKSPKTPNGPKPKRKKSKIATPATTPGPSA |
Length | 342 |
Position | Head |
Organism | Colletotrichum salicis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum>
Colletotrichum acutatum species complex.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.620 |
Instability index | 42.18 |
Isoelectric point | 9.36 |
Molecular weight | 36596.67 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
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GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
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GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
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Interaction
Repeat regions
Repeats |
>MDP06643
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 314.50| 101| 116| 102| 209| 1
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102- 209 (146.48/91.94) KQTRQKNLDrgRMEAKPLAYYFVVGENIY.QAPTLGDLLSSRIESIAESmRKVLPAADSVRKWTPSLGHVYTQPTPPSALSrAKDGGAAAAAAAAADTPAAEgavNGSK
222- 323 (168.03/86.01) KDSTANALD..RLAEESFAIHMRHGGDYFdENPITGRPGDFHFASTGRK.DKIAPPPPPSQSQSSSSSQQASQAQPKPVIN.TKLAEEAKKEGKEGKSPKTP...NGPK
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