<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06588

Description "Mediator complex, subunit Med23"
SequenceMLRTPTTSSCGGSGGIPLTITTSAQSPNPSDMGDQSHHRSSASRAFQFHPARPAIVDLFNLYLGRNGRHKSDDLIREPPNKTQKRVTALNRDIPPCNGQFLSDFQQLQNQFPDHDQLRTVVESVLVSLVIQCSGHAPRAEFILFALNGLYSVGYICWDSFLPSLLSSVTSAEMSVGISSAASPQPAVSSTSLSNAGMLPSSAVALNFSNFQSPNPESPLISVHGIGSPSQSANEPSCTALSPVKSSDINSTGQQAAARGNMSRRDSAISTLRKLSCEIIFSALEANLKPTTHADIFYHMLNWLVNWDQWQQGSDEVDGVKSLKREKALFEWLHKCLDVVWMLIEDNKCRIPFYELLRSGLQFIENLPDDEALFTLILEVHRRRDMMAMHMQMLDQHLHCPTFGNQRLLCQAAINMLGESTANLRYSPITYPSVLGEPLHGEDIAFSIERGSLDWDRAMRCIRHALRNTPSPDWWRRVLLVAPCHRVHSQGPTPGAVFSSDMICEATIDRVIELLMLTNTDANCWQEWLIYSDVFFFLMKSGCIDFVDFVDRLVLRISEEDHQILRTNHVTWLLAQIIRAELVMSALNTDSRKMETTRKVLSFHKEAISSVSSNPQSILLDFITSCQTLRIWSLNSSTREYLNSEQLHKGKQIDEWWRQVSKGDHMMDYMNLDDRSVGMFWVVSYTMAQPACEMVMTWLTSAGHAELPGPNLQANEKISVMREVNPVPVSLLSGFSINLCLKLAFQMEDAMFSGQYVPNIAMVETYTRLLLIQPHSLFRSHLSHLHQRNSETFNKPAATLLMLEILNYRLFPLYRYQGKSKTLMYDVTKILSTLKGKRGDHRVFRLAENLCMNLIMSLREFFFVRREGKGPTEFTETLNRVTVVTLAIIIKTRGIADAEHLLYLQTMLEQILATSHHTWSDKTLCYFPAVLRDALIGRTDKRDLAIQAWQQAEATVIHQCTQLLSPPDDPTYVMTYISHSFPQHRQYLCAGAWVLMRGHPENINSANLGRVLREFSPEEVTANVYTMVDVLLHNIQLDLQHGHSLQDLILNACANLAHFIWNHELLPPDILLLALIDRDDDPHALRIVVNLLERQELQQRIKFYVANHDNPEHWLQNGIFKRIELQKSLGHHLSWKERYPTYFDDIAARLLPVIPLIIYRLIENDATDVADRVLQLFSSFLRYYPLNFTFVRDILAYFYGHLPGKLIFQILNVLDIKKMPFSESFLQRVNSSNAICPPLEYFASLLSGLVANVIPPLCNLKGEGSNQSGSTNAFECQKPFYQIQDPGTYTQLILETAVIEILSLPVTPAQIVSAFVQIIVHIQPTLIQSNHSFHESSNSSESCSALATSPSGGITDFLDGRRSNPSTTELDLPDFVSQSGYTYQKLSCVLIQACGLLLAQLPAEFHIQLYAEASRVIKESWWHADGGRSTIELDSAVGYALLDPTWAAQDNTSTALGNMVALLHAFFSNLPQEWLDKTHLLINNLRPVSSIAVLRIAFRIIGPLLPRLANAHSLFTKTLELLLSMMVDVFGRNSQPSPPVEASDITDLIDFLHHIVHYEGQGGPVQPNSKPKPDVLGLCGRAIENLRKDVQHLLSHLKTDGNCSIYAAAATNPKLSQNLS
Length1619
PositionTail
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.08
Grand average of hydropathy-0.097
Instability index48.28
Isoelectric point6.15
Molecular weight182260.69
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06588
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     289.17|      72|     193|    1339|    1412|       1
---------------------------------------------------------------------------
  236-  297 (88.78/45.26)	SCTALSPVKSSDINS........TGQQAAARGNMSRRDSAIS....TLRKLSCEII..FSALEANLKPTTHADIfY...
 1341- 1412 (121.25/70.56)	SCSALATSPSGGITDFL......DGRRSNPSTTELDLPDFVSQSGYTYQKLSCVLIQACGLLLAQLPAEFHIQL.YAEA
 1546- 1608 (79.14/41.73)	...........DLIDFLhhivhyEGQGGPVQPNSKPKPDVLGLCGRAIENLR....KDVQHLLSHLKTDGNCSI.YAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     182.92|      57|     140|     870|     939|       2
---------------------------------------------------------------------------
  121-  165 (62.43/35.38)	VESVLVSLVIQCSGHAPrAEFILF...ALNGLYSVGYICWD....SFLPSLL.........
  880-  939 (94.47/91.67)	VTVVTLAIIIKTRGIAD.AEHLLYlqtMLEQILATSHHTWSDKTLCYFPAVLRDALIGRTD
 1057- 1079 (26.02/ 7.92)	....................................HFIWNHELL..PPDILLLALIDRDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.96|      30|     193|     330|     365|       5
---------------------------------------------------------------------------
  336-  365 (54.36/47.68)	LDVVWMLIEDNKCRI..PFYELLRSG.LQFIEN
  527-  547 (21.63/ 7.46)	....WLIYSD.......VFFFLMKSGcIDFVD.
 1441- 1468 (39.97/18.95)	LDPTWA.AQDNTSTAlgNMVALLHA....FFSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.46|      30|      47|     781|     810|       6
---------------------------------------------------------------------------
  781-  810 (51.81/36.95)	LSHLH.QRNSETFNKPAATLLMLEILNYRLF
  830-  860 (47.66/33.34)	LSTLKgKRGDHRVFRLAENLCMNLIMSLREF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.38|      49|     762|     706|     770|       7
---------------------------------------------------------------------------
  706-  770 (66.57/70.65)	LPGPNL.QANEKISVMREVNpvpvsllsgfSINLcLKLAFQMedamfSGQYVPNIAMVET.YTR...LLL
 1469- 1522 (70.81/39.87)	LPQEWLdKTHLLINNLRPVS..........SIAV.LRIAFRI.....IGPLLPRLANAHSlFTKtleLLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     206.53|      66|     768|     423|     490|       8
---------------------------------------------------------------------------
  423-  490 (118.06/101.42)	LRYSPITYPSV...LG...EPLHGEDIaFSIeRGSLDWDRA......MRCIRHALRNTPSPDWWRRVL..LVA....PCHRVHSQG
 1180- 1263 (88.48/65.94)	LRYYPLNFTFVrdiLAyfyGHLPGKLI.FQI.LNVLDIKKMpfsesfLQRVNSSNAICPPLEYFASLLsgLVAnvipPLCNLKGEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.55|      21|     868|      94|     116|      10
---------------------------------------------------------------------------
   94-  116 (37.36/29.89)	PPCNGQFLSDFqqLQNQFPDHDQ
  965-  985 (42.19/26.90)	PPDDPTYVMTY..ISHSFPQHRQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06588 with Med23 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MLRTPTTSSCGGSGGIPLTITTSAQSPNPSDMGDQSHHRSSASRAF
1
46










Molecular Recognition Features






MoRF SequenceStartStop




1) LFNLYLG
58
64