<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06566
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MNTSGCVSCSKLGLIAYGDSSSTNSNLCITFLETVNGINWRFHPPKQYSIHNQLHEEQNSNSNKKGVNLFYDLRSVHWNNWSLLNGELLAVCDDLGNMTMLTAGQTRDGNGTYHKMTVLFQDNVYKIHNQIIPLDTVSKKEGSLKVDRKHTKKEYGSTILDFQWIGNQKPEIAQIKAQRDPMTNTFESQMQQCPPSGVFHPASVKNACIAIRRNGHTDLWYQFSNTLDYKKISLQLTKNKESEWLRHARIAHMDVEQSFLVGMYSNISKCFSYYELQVDWNLSHKDPSMVLDPKLNLKHIFRANPDTMGPNGELLKLENFHIISKKALQGSRPEILISYNILGTTKTLVRRFEMIKTTPNMVFLSSFGVNISNANGSSKLSRYTLKHVQDLVFEHKVLDIQPHALDSLVAFRLQNGEMHFYNRYTWKLEEDSEASSVPYTKDSIFSIFATGFVFPNIPPIDAVEWCINSPSSGGVIVKLKQNKGPQFLTLKTKVTEDPSKDTIHATAFAFEFFRFNNRLHSGEDLVIAIKTHILKLQQIDANRAVDFIFIIISTILKLYGIQFEGPKEVLDKLLQSKAIQKLLLLQMELGSHLQNRTVFSMAYAAMKLRSIKLAMNGVARNVHAMIQHTALVNSLPNGKGFQFAFSKQDLIYSLIPSINWFVTFVTFLTQQLILLVNNPADKTHSLVIGIFSSITTRQLMLKLVMELKNLIGLITKFPETNYTILNESSNFLRKALGDSPVNLEKFETFLTDVNSKFASLADQDVTANTKREPYFLVKADIPPDIAHMKEFLLSYASTAMLSYINLAEVFFASTGTLRIFDSERFNPKISGLLQPLSAGLVVDDEALPNSVKESRAFSPLDYDDISSEWVDMSTIPCIKRCTRCGCITRAGNVVDTKHTVLETAIVTKRWTALYSRYCQCTGLLYELELDTSD |
Length | 933 |
Position | Tail |
Organism | Eremothecium sinecaudum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Eremothecium.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.174 |
Instability index | 34.94 |
Isoelectric point | 8.57 |
Molecular weight | 105647.20 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP06566
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 127.68| 42| 369| 223| 296| 8
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223- 273 (59.67/56.74) FSntLDYKKI...SLQLTKNKEsewlrhARIAHMDVEQSFLVGMYSNiSKCFSY
599- 643 (68.00/ 7.00) FS..MAYAAMklrSIKLAMNGV......ARNVHAMIQHTALVNSLPN.GKGFQF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 68.54| 20| 716| 16| 36| 9
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16- 36 (32.55/27.60) AYGDsSSTNSNLCITFLETVN
735- 754 (35.98/25.21) ALGD.SPVNLEKFETFLTDVN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.68| 14| 745| 106| 119| 10
---------------------------------------------------------------------------
106- 119 (27.46/16.53) TRDGNGTYHKMTVL
888- 901 (25.21/14.66) TRAGNVVDTKHTVL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 48.40| 14| 209| 644| 660| 14
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644- 660 (19.61/21.29) AFSKQDliYSLIPSiNW
856- 869 (28.79/17.23) AFSPLD..YDDISS.EW
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