<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06554

Description Uncharacterized protein
SequenceMSRAPPPYPGSTATSGGASSTTRGRNHAATSKAGAGGNGAAGSSAAQAISAAETSHSYRLSPIDGILAEQGLERYHLEPPSWRAPWILRPPPGSSAQADRPPASNATVGLGPNKSLIRLAGAPAPVAGPGGATSSLSTTDGDGGCTAWPVFYPPHDGMDEDRLTEQVVKHGFAAKSLVQAETFSAHQHIYEKLKSGDILGNLSRLVSAVRTKAETQLPTYGPSTFRLPSRITLTDSKREAWFSDLASPSIPLSKLSRSVPHGYKGEKGLDMLAHRKVQVDRAVWFVRAFGGVEIQSLAKTRPQATAIYLYTTEFTSVVCDFLRKQLSEVLLPRGGTTAPAATTVPPTHASPLGPPLTTTATTARARSGSLSMQAKAAAASAAAAAVAANTAAANANENGAGGLLDEEKRKAWEDKYEYTVKLTASLYHECLLDRLQFLHFLVSLLESSRSSTPSDTLGQLSFIVTLIEDYCDDILENEPETARLASGCMTRLDELEGVPDSSLRNRLRSALQVLVRKSFGRHPDSFASLFPTPIFPSPAFSPTDPAKLQSLIQAGPVSPDGSSCTSAEEAAMRDSIYADLADLRARRQLLSATLQENLTTAAPDSAMEDRARLAAIEHLDAFEFPHRVRDTHRSIFLAPTASHSLTWPEALPLFFTYAITPSRPCSGHRRYLVAQLIWMERERLQSGKKRVTRSAALLADPSTLPGAELRVEDAFVRWIDTLDPDLAEKHDVRLLAEELFRAGVMNYGAYLQRMIARGETERDLDSDGESNHLWVLRTVPLDPSLAEVKRRVAVSDKAPAKPTRAVEPKLAQARHDVEQLFGAAAVPDLLGSVRQLVGDGSQWAVTRDILPTAVSGRIDRATGRLNISRDVLAVTCQVYQSVKDWAGLLQLLTVMMQLRPSDEVLTHIIDIVHSRLDIWASLDVLSDLGAALFGAFQQSKLDSPTVNRRLLQLLCEFGESGLIDQEAQTTLRQELQTLASAASPSSDRQSPPALPIPLPEMQALQADASAEAVTKVASSLWHRYRYHPNWITALLDSAILYIRQLATIEPLVDLIRQLEAKMPLGGFSSALAPWTAGMRAAQAETLFGGPSGEATASFFAELAIAGVFHPIAVQQHLVAPARRVMLRLLLQAGSAADVGAHVTTVLRNIQRILAPIVGNLASEGARSVDSVADLPRRQMIASRRSSLTRHAGLPSIAGALASLIVEQEVAARLGLDAHAQATGAYFVRLASLPRLQALSSRAPKALRDGMLDCAELNSLPGVKELRPNLLAGLLVILKDGGAASPASLGSTEELDIFLSGLTIWRLNISKVEVVACLERLELDPSISASERYAALHTLSKHFLERVCSGDGKSYLGEQVVRCYSGPASDELVSVAFERLAGAVRELIAASLDKEKQEQPELVLRTTSALLDKLLQNSTANGRTKSIDELLESVRDLLVHQAQSRSDPEEAAKHQHALRPAHLVVLALRCAGKSTGKRTAELFRDCLALIAANAASCVREGLRHTQLATLLLDACSAILYALPDLSSTLRAPTFSSLANAPFPCGLSCDGIPDPVLDRLVRLFGPFVPTSPVRNPWELLDHADPTTTHSAIARKAAAASDKFLPPPTQLVNLGPIDLATFRARIIATIPAVTALDASSNVSTSSAHSNNSSNGAHRFEKGRQTNFDFETPCTTLSVSARDHRRTLNVTRLVSSRLEAAAAAGAHVAASAANAAAQLKASSASASKAGTPTAAATQAAAPAGRGVKRRNSQQQHPAAEVVVIDSDDDTAPGAAGLAKTGATQAKAKKAKTTSTGSAGGTSQAATGRIASKTTAGKAPGKTTRKRKAAA
Length1826
PositionKinase
OrganismRhodotorula sp. JG-1b
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Sporidiobolales> Sporidiobolaceae> Rhodotorula> unclassified Rhodotorula.
Aromaticity0.05
Grand average of hydropathy-0.133
Instability index46.38
Isoelectric point8.66
Molecular weight194576.54
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06554
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     190.86|      65|      83|     682|     764|       1
---------------------------------------------------------------------------
  693-  764 (99.54/85.41)	RSAALlaDPStLPGAELRV...EDAFVRWIDTLDPDLAE.KHDVrllaEELF.RAGVMNYGAYLQRMIARG...ETERDL
  777-  849 (91.31/45.61)	RTVPL..DPS.LAEVKRRVavsDKAPAKPTRAVEPKLAQaRHDV....EQLFgAAAVPDLLGSVRQLVGDGsqwAVTRDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.74|      30|      61|    1164|    1193|       2
---------------------------------------------------------------------------
 1164- 1193 (52.05/30.60)	GARSVDSVADLPRRQMIASRRSSLTRHAGL
 1223- 1251 (48.18/27.67)	GAYFV.RLASLPRLQALSSRAPKALRDGML
 1255- 1273 (30.50/14.31)	ELNSLPGVKEL.........RPNLL..AGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     335.60|      58|      59|    1668|    1725|       3
---------------------------------------------------------------------------
    9-   57 (60.63/23.61)	.PGSTATSGGAS.....STTRGRNHA..ATS...........KAGAGGNGAAGSSAAQaISAAET...SHS..
   92-  128 (41.39/13.64)	.PGSSA.QADRPPASNATVGLGPNKSLIRLA...........GAPAPVAG.......................
  345-  400 (79.16/33.22)	.PPTHASPLGPPLTTTATTARARSGSLSMQA...........KAAAASAAAAA.VAAN.TAAANA...NENGA
 1668- 1725 (85.79/36.66)	TPCTTLSVSARDHRRTLNVTRLVSSRLEAAA...........AAGAHVAASAANAAAQ.LKASSA...SASKA
 1727- 1794 (68.62/27.75)	TPTAAATQAAAPAGR..GVKRRNSQQQHPAAevvvidsdddtAPGA..AGLAKTGATQ.AKAKKAkttSTGSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.01|      39|      59|     854|     892|       4
---------------------------------------------------------------------------
  854-  892 (69.20/40.44)	VSGRIDRATGRLNI..SRDVL....AVTCQVYQSVK.DWAG....LLQLL
  905-  954 (46.81/25.10)	LTHIIDIVHSRLDIwaSLDVLsdlgAALFGAFQQSKlDSPTvnrrLLQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     246.67|      78|     256|     197|     302|       5
---------------------------------------------------------------------------
  197-  279 (124.35/78.14)	DILGN...LSRLVSAVRTKAEtQLPTYGPSTFRLPSRITLTDSKREAW......FSDL.ASPSIPLSKLSRSVPHgykgEKGLDMLA..HRKVQV
  404-  444 (42.91/13.61)	.......................................LDEEKRKAW.......EDK.YEYTV...KLTASLYH....ECLLDRLQflHFLVSL
  473-  545 (79.42/58.01)	DILENepeTARLASGCMTRLD.ELEGVPDSSLRNRLRSALQVLVRKSFgrhpdsFASLfPTPIFPSPAFSPTDP.....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.82|      26|      89|    1104|    1136|       7
---------------------------------------------------------------------------
 1104- 1136 (37.70/32.74)	IAGVFHPIAVQQHLVAparrvmlRLLLQAGSAA
 1196- 1221 (42.13/21.95)	IAGALASLIVEQEVAA.......RLGLDAHAQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.47|      24|      57|    1578|    1601|       9
---------------------------------------------------------------------------
 1578- 1601 (39.55/25.81)	LDHADPTTTHSAIARKAAAASDKF
 1633- 1656 (39.92/26.14)	LDASSNVSTSSAHSNNSSNGAHRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.29|      23|      90|     962|     984|      10
---------------------------------------------------------------------------
  962-  984 (36.20/23.79)	LIDQEAQTTLRQELQTLASAASP
 1051- 1073 (37.09/24.60)	LVDLIRQLEAKMPLGGFSSALAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.30|      13|      17|    1308|    1320|      14
---------------------------------------------------------------------------
 1308- 1320 (21.53/14.28)	ISKVEVVACLERL
 1326- 1338 (21.77/14.53)	ISASERYAALHTL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06554 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EPPSWRAPWILRPPPGSSAQADRPPASNATVGLGP
2) GGTTAPAATTVPPTHASPLGPPLTTTATTAR
3) LKASSASASKAGTPTAAATQAAAPAGRGVKRRNSQQQHPAAEVVVIDSDDDTAPGAAGLAKTGATQAKAKKAKTTSTGSAGGTSQAATGRIASKTTAGKAPGKTTRKRKAAA
4) MSRAPPPYPGSTATSGGASSTTRGRNHAATSKAGAGGNGAAGSSAAQAISAAETS
78
334
1715
1
112
364
1826
55










Molecular Recognition Features






MoRF SequenceStartStop




1) ATQAKAKKAKTTSTGSA
2) TSQAATGRIASKTTAGKAPGKTTRKRKAAA
1778
1797
1794
1826