<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06528

Description FF domain-containing protein
SequenceMQVKKLERYVLIEATIIAINSLLDPCLTYYHNKKTKLSSWEKPLDLMSPIERADASTDWKEYTAPDGRKYYYNKGTKQSKWKMPDELKLARQQMKTKSSTEEQEPTKDPDYEASAPSVTGLVSLARDADSPSSGAHEIVSSPVSVAPLVAAAQSGPVVTAEFSTGSRPSSNATSNAAEGQDDLKTVPITSEETEVPATLLNPAAPALSNTEDVSAKDSVAAENGPPAGNIEESEKGNVINHGANFMEEKTLDQENQDAKIAFKALLENANIASDWTWDQAMRVIINDRRYGALRTLSERKQAFNEFLGQKKKKEAEERRNRQKKAREEFKKMLDDSKEITSSTKWSKAIAIFEDDDRFKAVERSKDREDLFEDHIMELEKKERSKALEEHKRNRKEFIEFLKSCDFITASSQWRKVQDRLEADESCLRLEKVDRLEIFQVLVLDFFFAIDSDGEDLFHSIAGYLCQLTKEKDEEEQRKLRMEELRKTERKNREEFRKLMEGHIASGMLTSKTHWRDYCIKVKDLPAYLAVSSNSSGATPKDLFEDVIEELEKQYLEDRDQIKEAVKMRKVSISSTWTLEEFKSAIAEDISSYTISDVNLKLVFDELQERVREREEKETKRRKRLADDFYLSLSTSKEITSSSRWEDLKPLFEDRLESWFTVEESFYREIFDKYMTELKKARDERKHREEKAKKTVDRDRRTSSKSRRDKERGKKDKRRKEETDSDNGEENRRSGREKDKKHRKRHHQSYLEDMSLEEDEKEKDRSHRHSIERKRTKQQQLEQQSSATAGSVEYESRHKRYKRDHRHYDDQKEAEDGEVW
Length819
PositionUnknown
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.07
Grand average of hydropathy-1.114
Instability index60.22
Isoelectric point5.99
Molecular weight95468.33
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06528
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.65|      24|      24|     675|     698|       1
---------------------------------------------------------------------------
  675-  698 (40.24/19.04)	TELKKARD.ERKHREEKAKKTVDRD
  701-  725 (28.41/11.07)	TSSKSRRDkERGKKDKRRKEETDSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.65|      24|      24|     735|     758|       2
---------------------------------------------------------------------------
  735-  758 (45.41/22.78)	REKDKKH.....RKRHHQSYLEDMS......LEED
  760-  794 (27.79/11.34)	KEKDRSHrhsieRKRTKQQQLEQQSsatagsVEYE
  796-  815 (35.45/16.32)	RHKRYK........RDHRHY.DDQK......EAED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     128.70|      24|      24|     349|     372|       3
---------------------------------------------------------------------------
  349-  372 (40.10/19.96)	IAIFEDDDRFKAVERSK.DREDLFE
  375-  399 (32.17/14.59)	IMELEKKERSKALEEHKrNRKEFIE
  417-  438 (28.99/12.44)	QDRLEADESCLRLEKV..DRLEIF.
  653-  671 (27.44/11.39)	.DRL...ESWFTVEESF.YR.EIFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.55|      18|      38|      29|      46|       5
---------------------------------------------------------------------------
   29-   46 (36.01/21.15)	YYHNKKTKLSSWEKPLDL
   70-   87 (37.54/22.34)	YYYNKGTKQSKWKMPDEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     154.47|      42|      43|     221|     262|       6
---------------------------------------------------------------------------
  191-  219 (27.29/13.53)	............EETEvPATLLNPAAPALS....NTEDVSAKDSV
  221-  262 (71.06/47.19)	A..ENGPPAGNIEESE.KGNVINHGANFMEEKTLDQENQDAKIAF
  264-  303 (56.13/35.71)	AllENANIASDWTWDQ.AMRVIINDRRYGALRTLSERKQ....AF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     186.20|      37|     297|     309|     345|       7
---------------------------------------------------------------------------
  309-  345 (64.63/35.21)	QKKKKEAEER.......R.NRQKKA......R.......EEFKKMLDD...SKEITSSTKW
  469-  514 (41.98/20.11)	.KEKDEEEQRklrmeelR.KTERKN......R.......EEFRKLMEGhiaSGMLTSKTHW
  548-  593 (27.89/10.72)	EELEKQYLED.......R.DQIKEAvkmrkvSisstwtlEEFKSAI.....AEDISSYT..
  607-  644 (51.71/26.60)	QERVREREEK.......EtKRRKRL......A.......DDFYLSLST...SKEITSSSRW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06528 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ARDERKHREEKAKKTVDRDRRTSSKSRRDKERGKKDKRRKEETDSDNGEENRRSGREKDKKHRKRHHQSYLEDMSLEEDEKEKDRSHRHSIERKRTKQQQLEQQSSATAGSVEYESRHKRYKRDHRHYDDQKEAEDGEVW
2) KMPDELKLARQQMKTKSSTEEQEPTKDPDYEASAPSVTGLVSLARDADSPSSGAHEIVSSPVSVAPLVAAAQSGPVVTAEFSTGSRPSSNATSNAAEGQDDLKTVPITSEETEVPATLLNPAAPALSNTEDVSAKDSVAAENGPPAGNIEESEKGNVINHGANFMEEKTLDQ
680
82
819
253










Molecular Recognition Features






MoRF SequenceStartStop




1) GRKYYYN
2) GSVEYE
3) YLEDMSL
67
789
749
73
794
755