<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06527

Description FF domain-containing protein
SequenceMDNNPQNPGSQFRPVVPAQQGQPFMQSASGTQQYRAVGQGMPGQTQLPQFSQPMQMSSRPGQPGHPSPSSQAMPMPYMQPNMTFTSSSPQFQNSATTNSHVPSLGGPGVPLSSSYTFTAPSFGQPQNATNVSSQFHTVSQMHTPGASTGGQPWLSSGNQGPLTVSSVPQTGQQPSTTTPTNQASNVSNTSQDASSDWQEYTAGDGRRYYYNKRTKQSSWEKPLELMTPLEFVLCRYYYNKDTKQSKWTIPEELKLAREEAEKEASRGTQSEMATNPNASAVLTPSALDRPSASASSVNDVSSTAPRVASSPVAVAPVIPVGNVPPNVGSESSSTAAGERVTAVPLIPAVGGASMVSPMTSTENSSSHGVPKAVEVSAQDTEEAKKGMAVAGKVNTTQLEEKAVDDEPFIYASKQEAKIAFKSLLEDANVEADWNWEQAMRVIINDKRYGALKTLGERKQAFNEYLMQRKKLEAEERRLRQRKAKEEIPDAHPDSSDPGCTYHQQESKELTSSMRWSKAMAMFEDDERYKAVERPSDREDLFQNYLVDLQKKLLYISLCLFLSALHGFQFQERAKAQEEQRQYRLEYRQFLESCGLIKVDTQWRKVQDRLEDDERCSRLEKIDRLEIFQEYIRDLEKEEDEQRKIKKEHIKRVERKNRDEFRKMMEEHVISGALTAKTQWRDYCQKVKESVAYQAVASNTSGSTPKDLFEDVTEELEKKVLVSDFTHVHQWKIYEIESIGYHEDKTRVKDAMKLKKVTVAPTWTLEDFKVAIEEDIISSLSDVSLQVQEAVLRKLFTTAYNCFYGMIRLYVSFCKSNVFRVFYGWKCLGYFYLEMNVDESSLELVFEDLLERAKEKEEKEAKKRQRLAKDFTELLYDIKEITASSTWEECQQLFEESSEYRAVGDESLARETFEEYVARLLEKAKEKERKREEEKARKEEKERRKEKERREKEKEREEREREKDKKKDDSDIENLEIKEEKKREKEKDRKHRKRHQSSIVTDDVSSDKDEREDSGKKSRRHGSERKKSRKHAYSPESDSESKHKKHKRDSRKNGGGHEELEDGELGEDGEIQ
Length1071
PositionUnknown
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.07
Grand average of hydropathy-1.004
Instability index53.04
Isoelectric point5.98
Molecular weight122480.06
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06527
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     141.74|      25|      25|     939|     963|       1
---------------------------------------------------------------------------
  921-  944 (28.01/ 9.31)	..........EKAKEKERKREEEKARKEEKERRK
  945-  962 (22.79/ 6.38)	................EKERREKEKEREEREREK
  963-  995 (29.62/10.21)	D.kkkddsdiENLEIKEEKKREKEKDRKHRKRHQ
 1002- 1026 (36.37/13.99)	D.........VSSDKDEREDSGKKSRRHGSERKK
 1027- 1060 (24.95/ 7.59)	SrkhayspesDSESKHKKHKRDSRKNGGGHEELE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.80|      25|      25|     195|     219|       2
---------------------------------------------------------------------------
  195-  219 (51.28/35.16)	SDWQEYTAGDGR..RYYYNKRTKQSSW
  221-  247 (44.53/29.53)	KPLELMTPLEFVlcRYYYNKDTKQSKW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     409.28|      82|      84|     444|     527|       3
---------------------------------------------------------------------------
  365-  416 (54.17/21.37)	................................SSH.GVPKAVEVSAQDTEE......AKKGMAV....AGKVNTTQLEEKAVD.....DEPFIYASK.QE..A
  417-  506 (119.45/50.30)	KiafkslledaNVEA.DWNWEQAMRVIIND..KRY.GALKTLGERKQAFNEYL..MQRKKLEAE....ERRLRQRKAKEEIPDAHPDSSDPGCTYHQ.QE..S
  507-  592 (104.29/43.19)	K..........ELTS.SMRWSKAMAMFEDDE..RY.KAVERPSDREDLFQNYLvdLQKKLLYISlclfLSALHGFQFQER.AKAQEEQRQYRLEYRQfLE..S
  593-  670 (94.44/38.57)	C..........GLIKvDTQWRKVQDRLEDDER...cSRLEKI.DRLEIFQEYI..RDLEKEEDE....QRKIK....KEHIKRVERKNRDEFRKMME.EHviS
  878-  915 (36.93/11.62)	K..........EITA.SSTWEECQQLFEESSE..Y.RAVGDESLARETFEEY...................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      98.20|      16|      17|      48|      63|       4
---------------------------------------------------------------------------
   48-   63 (37.15/19.19)	PQFSQPMQM....SSR.P..GQP
   68-   80 (20.79/ 7.76)	PS.SQAMPM........P.yMQP
   89-  107 (18.69/ 6.30)	PQFQNSATT....NSHvPslGGP
  133-  152 (21.56/ 8.30)	SQFHTVSQMhtpgAST.G..GQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.84|      17|      19|     315|     331|       5
---------------------------------------------------------------------------
  297-  311 (17.25/ 8.55)	..VNDVSSTA..PRVASSP
  315-  331 (30.98/22.04)	APVIPVGNVP..PNVGSES
  335-  353 (21.61/12.83)	AAGERVTAVPliPAVGGAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.53|      12|      23|      11|      22|       6
---------------------------------------------------------------------------
   11-   22 (22.97/15.78)	QFRPVVPAQQGQ
   33-   44 (23.56/16.39)	QYRAVGQGMPGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.49|      11|      18|     165|     175|       7
---------------------------------------------------------------------------
  165-  175 (20.78/12.12)	SSVPQTGQQPS
  184-  194 (18.71/10.18)	SNVSNTSQDAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      90.25|      21|      48|     673|     693|       8
---------------------------------------------------------------------------
  673-  690 (25.94/16.23)	...........LTA..KTQWRDYCQKVKESV
  691-  719 (22.88/13.36)	AYQavasntsgSTP..KDLFEDVTEELEKKV
  724-  738 (20.08/10.73)	...........FTH..VHQWKIY..EI.ESI
  739-  758 (21.36/11.93)	GYH...........edKTRVKDAMKLKKVTV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06527 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVAPVIPVGNVPPNVGSESSSTAAGERVTAV
2) ERKREEEKARKEEKERRKEKERREKEKEREEREREKDKKKDDSDIENLEIKEEKKREKEKDRKHRKRHQSSIVTDDVSSDKDEREDSGKKSRRHGSERKKSRKHAYSPESDSESKHKKHKRDSRKNGGGHEELEDGELGEDGEIQ
3) GASMVSPMTSTENSSSHGVPKAVEVSAQDTEEAKKGMAVAGKVNTTQL
4) MDNNPQNPGSQFRPVVPAQQGQPFMQSASGTQQYRAVGQGMPGQTQLPQFSQPMQMSSRPGQPGHPSPSSQAMPMPYMQPNMTFTSSSPQFQNSATTNSHVPSLGGPGVPLSSSYTFTAPSFGQPQNATNVSSQFHTVSQMHTPGASTGGQPWLSSGNQGPLTVSSVPQTGQQPSTTTPTNQASNVSNTSQDASSDWQEYTA
5) WTIPEELKLAREEAEKEASRGTQSEMATNPNASAVLTPSALDRPSASASSVNDVSSTAPR
313
927
351
1
247
343
1071
398
202
306










Molecular Recognition Features






MoRF SequenceStartStop




1) GHEELEDGELGEDGEIQ
2) RKKSRKHAYSPESDSESKHKKHKRDSRKN
1055
1024
1071
1052