<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06517

Description "DNA helicase, ATP-dependent, RecQ type"
SequenceMRNNCSGRSRGADKPIRNNWSQHAKSHDNVLSEDKNFLFSLSRQKPSAEQAMTATARHNVTKAHSLQVDKAWQALSNLKLSSRNYIKPGKSRPIAKDGDTASFRDVERATQQCSSEANNKSTRSTWGDQHSNEINIMHSKPRRMTDLFASVTTSVTEAGRAETMQSGGYVLNSTNVCGRDEGGIHKNHAKISSHLHGLQEIDAGGIDDEDILQNLDMDQITEHFQSSCTPRPSISKFPPFTPAASHTVAACEDISLPPELCVDCSHGFKARICPEAAGHLHVMKDQLISISNDLLDNVGELNSDQIEKLRQDRLQLNKQIQQLEKYLHYILMDEERHNSNFSAYTTTRTLQYGTPPTFTSMVDPVRLDDQFYMCNETNGHDRWDSSSVSCFSEGNVDDSSTSMEREPHAKRYVEVNYSEGSDDKKWSKRDFPWTKKLEANNKKVFGNHSFRPNQREVINATMSGKDVFVLMPTGGGKSLTYQLPALICPGVTLVISPLVSLIQDQIMHLLQANIPAAYLSANMEWSEQQEILRELCSGHCSYKLLYVTPEKVAKSNALLRQLENLYARELLDRIVIDEAHCVSQWGHDFRPDYQSLGILKHKFPNTPVLALTATATASVKEDVVQALGLVDCVIFRQSFNRPNLRFSVIPKTKKCMEDIDKFIKDNHFDECGIIYCLSRMDCEKVAEKLQDCGHKAAFYHGSMDPDQRAKVQKLWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQHASCVLYYSYSDYIRVKHMLSQGSVEQNSFASGYRSSTMNSGRVLETNTENLLGMVSYCENDVDCRRYLQLVHFGEKFDPVNCRKTCDSCFKNQSLVNKDVTGIAKHLVELVKSAQQNFSASHILEVYKGSMSQIVKKYQHNTLSLHGAGQNVAKGDALRVIRHLVIEEILVEDVKKSDLYGSVSSILKVNEKKAYDLLEGRQTIILSCGWCPTGNIPFGAPDLFINIGGGGETGMLPYDISAKGSPELKRSLSRLMALASK
Length1027
PositionUnknown
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.07
Grand average of hydropathy-0.485
Instability index46.04
Isoelectric point7.09
Molecular weight115032.86
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06517
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     232.22|      96|     366|     412|     571|       1
---------------------------------------------------------------------------
  391-  411 (-2.12/21.03)	FSEGNvDDSSTSMEREPHAKR.......................................................................................................................................
  417-  571 (121.50/181.06)	YSEGS.DDKKWSKRDFPWTKKleannkkvfgnhsfrpnqrevinatmsgkdvfvlmptgggksltyqlpaLICPGVTLVISPLVSLIQDQimhllQANIPAAYLSANMEWSEQQeILRELcsGHCSYKlLYVTPEKVAKSNAlLRQLENLYARELL
  861-  936 (112.84/53.01)	......................................................................LVNKDVTGIAKHLVELVKSA.....QQNFSASHILEVYKGSMSQ.IVKKY..QHNTLS.LHGAGQNVAKGDA.LRVIRHLVIEEIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     344.97|     105|     145|     672|     784|       2
---------------------------------------------------------------------------
  672-  784 (176.35/123.43)	GII.YCLSRMDCEKVAeKLQDCGHKAAFYHGSMDPDQRAKVQKLWSKDEINIICATVAFgmgINKPDVRFVIHHSLpksiEGYHQECGRAGRDGQHASCVLY.....YSYSDYIRV.KHM
  819-  930 (168.62/99.04)	GMVsYCENDVDCRRYL.QLVHFGEKFDPVNCRKTCDSCFKNQSLVNKDVTGIAKHLVEL...VKSAQQNFSASHIL....EVYKGSMSQIVKKYQHNTLSLHgagqnVAKGDALRViRHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.90|      37|     367|     206|     285|       3
---------------------------------------------------------------------------
  209-  254 (46.79/92.81)	EDILQNLDM.DQITehFQSSCTpRPSIsKFpPFTPAASHtvaaC.EDI
  621-  659 (59.10/17.09)	EDVVQALGLvDCVI..FRQSFN.RPNL.RF.SVIPKTKK....CmEDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.41|      23|     206|     363|     387|       4
---------------------------------------------------------------------------
  363-  387 (40.96/29.19)	DPVRLDDQfyMCNETNGHD.RWDSSS
  572-  595 (41.45/22.64)	DRIVIDEA..HCVSQWGHDfRPDYQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06517 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LSEDKNFLFSLSRQKPSAEQAMTATARHNVTKAHSLQV
2) SRNYIKPGKSRPIAKDGDTASFRDVERATQQCSSEANNKSTRSTWGDQHSNEINIMHSKPRR
31
82
68
143










Molecular Recognition Features






MoRF SequenceStartStop




NANANA