<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06512

Description "Coactivator CBP, KIX domain-containing protein"
SequenceMDTSNWRPTQGGSAGGGDSSMESADWRSQLQADSRQRIVNKIMDTLKRHLPFSGHEGLQELKKIAVRFEEKIYTAATSQSDYLRKISLKMLTMETRSQNSMSDAIQSNSAANSVNPSDPGSQVMQQVNNQGQPLPISVPSNHPQPGQQMLSQSIHNNISSTGMQGSSSLSSALPPGSGLPQSTMANGAGQNSSLQNIQNMSGVQQNSVGNTMGSGQPVVPQSSQPLIQHHQQSVLRQQRQQQQAPIAHQQQVQPSQAQQQQTQSQPNSMGQQANATNMQQNQLIGQQNSYSDMQQQRLLGQQNKLSSVQQPQQHLIGQHNNLSSMQQQHMVSQTGGGSVQQQQLLGTQSGNSSMQTNQHPAHMLQSKIPIQQQNQQSSATLLPTQVQQSQPQLQQQVMSHIQSQSGQLQQQVGMQQQPNLLQRDMQQRLPTSGGFQQQNVIDQQKQLFQQQRPMPEASSTSLDSTAQTGNPNGGDWQEEVYQKIKAMKDLYLLDLHDMHQKILGKLQQHDSLPQQPKNEQLEKLKVFKNMLERFMAFLQIPKHNILANYKDKLGTYEKQIVNVINSNRRKPAATQQQTQTLPPSHLPSVQQSQQTHSQLTQVQPHENQMNSQMQTVNLQGSMAAMQQNNMGSLQQNSVSSVSGASNAQQNMMSSIQPNSNLDSGQNSTMNSLQQQMTMKSGAFQQHHAAAQRSAYHQQLKSGAPFSPQLLPAASPQMSQHPSPQIDQQNLFNSLTKPGTPLQSANSPFAVPSPATPSASPIPGELMSGVSSLSNGGNLGHQQPTAAVLPSQSLAIGTPGISASPLLAEFTSPDGNHGVVASIGSGKSSVTEQPLDRLLKVVKSISPKALSASVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARTFVTQDGNNGTRKMKRFTSAMPLNVVSSVGSVNDSFKQLNCAGTSELDSTASSTIKRPRIETNHALLEEIKEINQGLIDTVVDISEEDNDPAAASEGGDGTVVKCSFCAVALGPNLKSQYASAQMSPIQPLRLLVPANYPNCSPILLDKFPIEVSKEYEDLSVKTKSRFSISLRSLSQPMSLKEIARTWDVCARAVISEYAQQSGGGTFSSKYGVWENCLSAA
Length1117
PositionTail
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.03
Grand average of hydropathy-0.655
Instability index65.12
Isoelectric point8.95
Molecular weight121039.80
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06512
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     313.24|      42|      43|     134|     175|       1
---------------------------------------------------------------------------
  134-  163 (46.69/ 9.51)	...............LPI....SVPSN.HPQP...GQQMLS......QSIHNNISSTGM
  164-  203 (44.57/ 8.76)	QGSSSLSSALPPgsgLPQ....STMAN...GA...GQNSSL......QNIQN...MSGV
  204-  242 (46.01/ 9.27)	Q.QNSVGNTMGS..gQPV.....VPQS..SQP...LIQHHQ......QSVLRQ.QRQQQ
  243-  293 (50.49/10.86)	QAPIAHQQQVQP...SQA....QQQQT.QSQPnsmGQQANAtnmqqnQLIGQQNSYSDM
  294-  325 (45.90/ 9.23)	QQQRLLGQQNKL...SSV....Q.......QP...QQHLIG......Q..HNNLSS..M
  336-  375 (37.07/ 6.11)	GGSVQQQQLLGT.qsGNS....SMQTNqHP......AHMLQ......SKI..PIQQQNQ
  626-  663 (42.51/ 8.03)	QQNN.....MGS...LQQnsvsSV.SG.ASNA...QQNMMS.......SI.QPNSNLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     317.00|      52|      55|     378|     429|       2
---------------------------------------------------------------------------
  378-  422 (71.59/23.97)	...............SATL.LPTQ..VQQSQ...P...QL...QQQVMSHIQSQS...............GQL..QQQVG..MQQQPNLLQ
  423-  449 (36.33/ 8.57)	RD.MQQR.L....ptS......................................................GGF..QQQNV..IDQQKQLFQ
  450-  520 (41.52/10.83)	....QQRpM...peaSSTS.LDST..AQTGN...PnggDW...QEEVYQKIKAMKdlylldlhdmhqkilGKL..QQHDS..LPQQPKNEQ
  528-  578 (37.72/ 9.17)	KN.MLER.F......MAFLqIPKHniLANYK...D...KLgtyEKQIVNVINSNR....................RKPAA..TQQQT....
  579-  619 (56.53/17.39)	.....QT.L......PPSH.LPS...VQQSQ.......QT...HSQ.LTQVQPHE...............NQM..NSQM.....QTVN.LQ
  692-  745 (42.20/11.13)	RSaYHQQ.LksgapfSPQL.LPAA.sPQMSQhpsP...QI...DQQ..NLFNS...................L..TKPGT..PLQSAN...
  746-  791 (31.11/ 6.29)	...............SPFA.VPSP..ATPSA...S...PI...PGELMSGVSSLS.............ngGNLghQQPTAavLPSQ.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.50|      18|      19|    1020|    1037|       3
---------------------------------------------------------------------------
 1020- 1037 (32.15/24.98)	SPIQPLRLLVPANYPNCS
 1039- 1056 (28.35/21.06)	ILLDKFPIEVSKEYEDLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.26|      13|      19|       1|      13|       4
---------------------------------------------------------------------------
    1-   13 (26.53/15.64)	MDTSNWRP.TQGGS
   21-   34 (19.73/ 9.74)	MESADWRSqLQADS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06512 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IVNVINSNRRKPAATQQQTQTLPPSHLPSVQQSQQTHSQLTQVQPHENQMNSQMQTVNLQGSMAAMQQNNMGSLQQNSVSSVSGASNAQQNMMSSIQPNSNLDSGQNSTMNSLQQQMTMKSGAFQQHHAAAQRSAYHQQLKSGAPFSPQLLPAASPQMSQHPSPQIDQQNLFNSLTKPGTPLQSANSPFAVPSPATPSASPIPGELMSGVSSLSNGGNLGHQQPTAAVLPSQSL
2) KISLKMLTMETRSQNSMSDAIQSNSAANSVNPSDPGSQVMQQVNNQGQPLPISVPSNHPQPGQQMLSQSIHNNISSTGMQGSSSLSSALPPGSGLPQSTMANGAGQNSSLQNIQNMSGVQQNSVGNTMGSGQPVVPQSSQPLIQHHQQSVLRQQRQQQQAPIAHQQQVQPSQAQQQQTQSQPNSMGQQANATNMQQNQLIGQQNSYSDMQQQRLLGQQNKLSSVQQPQQHLIGQHNNLSSMQQQHMVSQTGGGSVQQQQLLGTQSGNSSMQTNQHPAHMLQSKIPIQQQNQQSSATLLPTQVQQSQPQLQQQVMSHIQSQSGQLQQQVGMQQQPNLLQRDMQQRLPTSGGFQQQNVIDQQKQLFQQQRPMPEASSTSLDSTAQTGNPNGGDWQEE
3) MDTSNWRPTQGGSAGGGDSSMESADWRSQLQADS
560
85
1
793
479
34










Molecular Recognition Features






MoRF SequenceStartStop




NANANA