<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06510

Description "Protein kinase, ATP binding site-containing protein"
SequenceMAVVNSVSAQGAQRIDQIRYPVVDNSEIMEIRGEIVEETSPREVEDKIYVAVGKDLKESQSILRWALHNSGGRQICILHVHQPAEKIPIMGTKFRINQLEAHQVKTFHDEERQTMHQLIDKYKQICREVGVSVEVQHIEMESIEKGIVELLLQHNSKKAIYVRLHAAASCQIQFICKGKIIFTRQSRLDGLGASISSPSLLPDTNSDSEQSSLRSKSVGGAQNTRLRLNSLTPEYHRGMSDNRGIRRPVITLPNDNLESTPVSRLNAGRASDEWSVISQRSPSIGSRLSTCSSDLVDDSALIPYATIGSGEIRSDYSAVPGFLEDIHRPSPPSVLEGGMNDELYDQLERAMAEAGNSRRDAFEESIRRRKAEKDAMEAKRRVKRSESLYANELRQRREIDEELEKTKEEHEDIKKELDEVAEELRMALEQKSFLESQVADFDQTIQELEQKMFSAVELLQNYKKERDELQVECDDALRSLEELREKQAEESSSSSTSRLYTEFSFSEIKDATCNFDPSLKIGEGGYGSIFRGFLRHTDVAIKMLNSHSLQGSSEFHQEYLSGGSLEDRLNCKDNTPPLSWQNRIRIAAELCSVLIFLHSCDIVHGDLKPANLLLDKNLVSKLSDFGICRVLSQTEFSSNYTSLCCRTSPKGTFVYMDPEFISTGELTSKSDTLLTGKSPLGLTKEVQHALNKENLKNILDPTAGDWPFVQAQQLALLAMNCCDVVRENRPDLASEVWKVLEPMRVSCGLSSFRFGAEGRCQIPHYFNCPIFQEMMQDPVVAADGYTYEAEALRGWLDSGHNTSPMTNLELANSNLVPNRALKSAIQEWLQQS
Length832
PositionTail
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.06
Grand average of hydropathy-0.504
Instability index54.39
Isoelectric point5.33
Molecular weight93679.47
Publications
PubMed=26786968

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06510
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.32|      27|      46|     343|     387|       2
---------------------------------------------------------------------------
  341-  368 (40.19/46.45)	DELY.DQL..ERAMAEAGNSRRDAFEEsIRR
  386-  415 (34.14/ 9.63)	ESLYaNELrqRREIDEELEKTKEEHED.IKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.92|      20|      46|     416|     435|       3
---------------------------------------------------------------------------
  416-  435 (33.78/21.38)	ELDEVAEELRMALEQKSFLE
  447-  455 (15.84/ 6.11)	E...........LEQKMFSA
  465-  482 (30.30/18.41)	ERDELQVECDDAL..RSLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     224.73|      70|     131|     501|     580|       4
---------------------------------------------------------------------------
  501-  580 (106.25/100.47)	TEFSfSEIKDATCNFDPslkigEGGYGSIFRGFLRHTDVAIK...MLNSHSLQGSSEFHQEYLSGGSLEDRLnckDNTPPlSW
  634-  706 (118.48/80.38)	TEFS.SNYTSLCCRTSP.....KGTFVYMDPEFISTGELTSKsdtLLTGKSPLGLTKEVQHALNKENLKNIL...DPTAG.DW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.58|      22|     144|     581|     602|       7
---------------------------------------------------------------------------
  581-  602 (38.37/24.38)	QNRIRIAAELCSVLIFLH.SCDI
  711-  724 (17.91/ 7.65)	......AQQL..ALLAMN.CCDV
  727-  749 (35.30/21.87)	ENRPDLASEVWKVLEPMRvSCGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06510 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVPGFLEDIHRPSPPSVLEGGMNDELYDQLERAMAEAGNSRRDAFEESIRRRK
318
370










Molecular Recognition Features






MoRF SequenceStartStop




1) LYDQL
343
347